Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hyung-yul Lee"'
Publikováno v:
Diabetes/Metabolism Research and Reviews. 30:23-30
Background Adenosine monophosphate-activated protein kinase (AMPK) is stimulated in embryos during diabetic pregnancy by maternal hyperglycaemia-induced embryo oxidative stress. Stimulation of AMPK disrupts embryo gene expression and causes neural tu
Publikováno v:
Systems Biology in Reproductive Medicine. 58:10-22
In light of various pressures, toxicologists have been searching for alternative methods for safety testing of chemicals. According to a recent policy in the European Union (Regulation, Evaluation Authorisation and Restriction of Chemicals, REACH), i
Publikováno v:
Shock. 36:580-585
This study tested the hypothesis that a novel mitochondria-targeted SS-31 peptide attenuates the burn injury-induced apoptosis and endoplasmic reticulum stress and improves insulin sensitivity in the skeletal muscle. Following 30% total body surface
Autor:
Jacqueline Pontes Monteiro, Jim Kaput, Noriko Nakamura, Amy L. Inselman, Hyung-yul Lee, Baitang Ning, Deborah K. Hansen, Vijayalakshmi Varma
Publikováno v:
European Journal of Pharmacology. 668:S108-S116
Throughout the last century, possible effects of exposure to toxicants, nutrients or drugs were examined primarily by studies of groups or populations. Individual variation in responses was acknowledged but could not be analyzed due to lack of inform
Autor:
Lisa L. Sandell, Sarah C. Morgan, Frédéric Relaix, Mary R. Loeken, John Levorse, Hyung-yul Lee
Publikováno v:
Mechanisms of Development. 125(9-10):757-767
During neural tube closure, Pax3 is required to inhibit p53-dependent apoptosis. Pax3 is also required for migration of cardiac neural crest (CNC) from the neural tube to the heart and septation of the primitive single cardiac outflow tract into the
Autor:
O. David Sherwood, Hyung-Yul Lee
Publikováno v:
Biology of Reproduction. 73:790-797
Serum levels of the ovarian hormones relaxin, estrogen, and progesterone are elevated during the second half of 23-day rat pregnancy when dramatic growth of the cervix occurs. Recently, we demonstrated that relaxin contributes to cervical growth by b
Publikováno v:
Endocrinology. 146:511-518
Relaxin promotes marked growth of the cervix during the second half of rat pregnancy, and this growth is accompanied by an increase in both epithelial and stromal cells. The objective of this study was to test the hypothesis that the extent to which
Autor:
Barry Yedvobnick, Hyung Yul Lee, Matthew Ammerman, Annette L. Parks, Marc A. T. Muskavitch, Whitney Helms
Publikováno v:
Developmental Biology. 215:358-374
The phenotypes and genetic interactions associated with mutations in the Drosophila mastermind (mam) gene have implicated it as a component of the Notch signaling pathway. However, its function and site of action within many tissues requiring Notch s
Autor:
Hyung-Yul, Lee, O David, Sherwood
Publikováno v:
Biology of reproduction. 73(4)
Serum levels of the ovarian hormones relaxin, estrogen, and progesterone are elevated during the second half of 23-day rat pregnancy when dramatic growth of the cervix occurs. Recently, we demonstrated that relaxin contributes to cervical growth by b
Publikováno v:
Annals of the New York Academy of Sciences. 1041
This study compares the bioactivity of porcine relaxin-1 to that of recombinant human relaxin-2 in mice and rats. The effects of the two hormone preparations on elongation of the mouse interpubic ligament and both the wet weight and the extensibility