Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hyung-Sup Jang"'
Autor:
Moonseok Choi, Hyung-Sup Jang, Taekwon Son, Dongsoo Kim, Young-Jin Youn, Gyu-Bin Hwang, Young Pyo Choi, Yun Ha Jeong
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15064 (2023)
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid β (Aβ) plaques in the brain, leading to cognitive impairment and other clinical symptoms. The 5XFAD mouse model is commonly used in AD research because it expresses five hum
Externí odkaz:
https://doaj.org/article/fd62d19f5dfc4e3283b34a7be4452f32
Publikováno v:
Han, J, Jang, H, Green, A J E & Choi, Y P 2020, ' RT-QuIC-based detection of alpha-synuclein seeding activity in brains of dementia with Lewy Body patients and of a transgenic mouse model of synucleinopathy ', Prion, vol. 14, no. 1, pp. 88-94 . https://doi.org/10.1080/19336896.2020.1724608
Prion
Prion
RT-QuIC is a shaking-based cyclic amplification technique originally developed in the prion field to detect minute amounts of scrapie prion protein (PrPSc). In this study, we applied the RT-QuIC assay to investigate a-synuclein (a-syn) seeding activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33a3184ad2a2349133febf107b3c337
https://doi.org/10.1080/19336896.2020.1724608
https://doi.org/10.1080/19336896.2020.1724608
Autor:
Shogo Endo, Hee Kyung Jin, Hyung Sup Jang, Min Seock Jeong, Jae-sung Bae, Min Hee Park, Ju Youn Lee
Publikováno v:
BMB Reports
Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency of NPC1 gene function, which leads to severe neuroinflammation such as astrogliosis. While reports demonstrating neuroinflammation are prevalent in NP-C,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ce84b7eb8524a30d173c4247217e0d
https://doi.org/10.5483/bmbrep.2018.51.2.168
https://doi.org/10.5483/bmbrep.2018.51.2.168