Zobrazeno 1 - 10 of 83 pro vyhledávání: '"Hyung-Sun Youn"'
1
Diesel exhaust particle exposure accelerates oxidative DNA damage and cytotoxicity in normal human bronchial epithelial cells through PD-L1
Autor: Minji Kwon, Jiwoo Jung, Hee Sun Park, Na Hui Kim, Jiwoo Lee, Jayeon Park, Youjin Kim, Seokwon Shin, Byung Soo Lee, Ye Hwang Cheong, Hyung-Sun Youn, Sung Roul Kim, Sin-Aye Park
Publikováno v: Environmental Pollution. 317:120705
Diesel exhaust particles (DEPs) are a major cause of cancer progression as well as a variety of acute and chronic diseases. It is well-known that programmed death-ligand 1 (PD-L1) is an immune checkpoint molecule that can induce immune escape in tumo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad50f0b03612015726f8038ec17fb14
https://doi.org/10.1016/j.envpol.2022.120705
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2
Isobavachalcone suppresses the TRIF-dependent signaling pathway of Toll-like receptors
Autor: Seokwon Shin, Jayeon Park, Ye Eun Lee, Hanbin Ko, Hyung‐Sun Youn
Publikováno v: Archiv der PharmazieREFERENCES. 355(3)
Toll-like receptors (TLRs) are integral membrane-bound receptors that are central to innate and adaptive immune responses. They are known to activate a cascade of downstream signals to induce the secretion of inflammatory cytokines, chemokines, and t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04e968bc5e6b82225846c1ce9a81e50
https://pubmed.ncbi.nlm.nih.gov/34964142
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3
Sauchinone inhibits the proliferation, migration and invasion of breast cancer cells by suppressing Akt-CREB-MMP13 signaling pathway
Autor: Nam Ji Sung, Na Hui Kim, Deok-Seon Ryu, Sin-Aye Park, Seokwon Shin, Hyung-Sun Youn
Publikováno v: Bioscience Reports
Sauchinone, a lignan isolated from Saururus chinenesis, is known to exhibit anti-inflammatory and anti-oxidant effects. Recently, sauchinone has been reported to inhibit the growth of various cancer cells, but its effects on breast cancer cells remai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a973a345546e42e5abcb5cc6ea6aac90
https://doi.org/10.1042/bsr20211067
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6
Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells
Autor: Hyung-Sun Youn, Na Hui Kim, Nam Ji Sung, Sin-Aye Park
Publikováno v: Biochemical and biophysical research communications. 533(4)
Gremlin-1 (GREM1), one of the antagonists of bone morphogenetic proteins (BMPs), has recently been reported to be overexpressed in a variety of cancers including breast cancer. GREM1 is involved in tumor promotion, but little is known about its role
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e1a5edcbd66d4c58b93d07006a4698
https://pubmed.ncbi.nlm.nih.gov/33097188
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7
Differential regulation of MyD88- and TRIF-dependent signaling pathways of Toll-like receptors by cardamonin
Autor: Su Yeon Kim, Hyung-Sun Youn, Hyun-Jin Shim, Ah-Yeon Kim, Sunghye Heo
Publikováno v: International Immunopharmacology. 64:1-9
Toll-like receptors (TLRs) play a crucial role in the induction of innate immune response against bacterial and viral infections. TLRs induce downstream signaling via MyD88- and TRIF-dependent pathways. Cardamonin is a naturally occurring chalcone fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e29b1e18042f42d055e3a09b8aff0c
https://doi.org/10.1016/j.intimp.2018.08.018
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