Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hyung-Hwan Hyun"'
Publikováno v:
Biotechnology and Bioprocess Engineering. 18:770-777
The fed-batch culture system was employed to enhance production of α-ketoglutarate (α-KG) by the strainsof Corynebacterium glutamicum, whose genes encoding the key enzymes responsible for the biosynthesis of L-glutamate from α-KG were deleted. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b6049ea0c5b915fffb16ace2e863f8
https://doi.org/10.1007/s12257-013-0106-x
https://doi.org/10.1007/s12257-013-0106-x
Publikováno v:
The Journal of Microbiology. 49:53-57
Corynebacterium ammoniagenes N424 was metabolically modified to isolate overproducers of deoxycytidine. Inosine auxotrophy (ino) was initially introduced to prevent the flow of PRPP (phosphoribosyl pyrophosphate) into the purine biosynthetic pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbe7491471f710338cc2c97645ac82a
https://doi.org/10.1007/s12275-011-0195-1
https://doi.org/10.1007/s12275-011-0195-1
Publikováno v:
Biotechnology Letters. 33:71-78
Thymidine is an important precursor in antiviral drugs. We have enhanced thymidine production in E. coli by eliminating the repressors in the transcription of the gene coding for carbamoyl phosphate synthetase. The operon for carbamoyl phosphate synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c6b6978d5e57bcb7cfacd159734f20
https://doi.org/10.1007/s10529-010-0413-7
https://doi.org/10.1007/s10529-010-0413-7
Publikováno v:
Biotechnology Letters. 32:1089-1094
The mdh gene encodes mannitol dehydrogenase (MDH), which catalyzes the conversion of fructose into mannitol. The putative mdh gene of Candida magnoliae was isolated by PCR using the primers deduced from the N-terminal amino acid sequences of an intac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b55a96b9bbe4df7b54efc23d20cc84b
https://doi.org/10.1007/s10529-010-0257-1
https://doi.org/10.1007/s10529-010-0257-1
Publikováno v:
Microbial Cell Factories
Background Rational engineering studies for deoxycytidine production were initiated due to low intracellular levels and tight regulation. To achieve high-level production of deoxycytidine, a useful precursor of decitabine, genes related to feed-back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd817e9926d5f6f15f955b0cdf0eb96
https://doi.org/10.1186/s12934-015-0291-8
https://doi.org/10.1186/s12934-015-0291-8
Additional file 1: In the Supplemental Figure Section results from strain screening experiment and respective SDS-PAGE harboring each plasmid with map as well as HPLC profiles are presented. In the Supplemental Table Section the original data of tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a4bb9719300d84c387a4f65fdf39e0
Publikováno v:
Journal of Biotechnology. 121:54-61
To enhance the production of micrococcin GO5, a bacteriocin produced by Micrococcus sp. GO5, cultivation conditions and medium composition were optimized. The optimal initial pH and temperature for bacteriocin production were 7.0-9.0 and 37 degrees C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85653185e1619b195be9fa36928c034c
https://doi.org/10.1016/j.jbiotec.2005.06.022
https://doi.org/10.1016/j.jbiotec.2005.06.022
Publikováno v:
Journal of Food Protection. 68:157-163
Strain GO5, a bacteriocin-producing bacterium, was isolated from green onion kimchi and identified as Micrococcus sp. The bacteriocin, micrococcin GO5, displayed a broad spectrum of inhibitory activity against a variety of pathogenic and nonpathogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d2d4f481dd61c3ab17c34bc37d7f15
https://doi.org/10.4315/0362-028x-68.1.157
https://doi.org/10.4315/0362-028x-68.1.157
Autor:
Harini Krishnamurthy, J. Gregory Zeikus, Claire Vieille, Honggao Yan, Alexei Savchenko, Hyung Hwan Hyun
Publikováno v:
Biochemical Journal. 372:577-585
The adenylate kinase (AK) gene from Thermotoga neapolitana, a hyperthermophilic bacterium, was cloned and overexpressed in Escherichia coli, and the recombinant enzyme was biochemically characterized. The T. neapolitana AK (TNAK) sequence indicates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7891dcd758989987f66c15982ebc546
https://doi.org/10.1042/bj20021377
https://doi.org/10.1042/bj20021377
Publikováno v:
Biotechnology Letters. 25:761-765
The most efficient substrate for mannitol production by Candida magnoliae HH-01 is fructose; glucose and sucrose can also be converted into mannitol but with lower conversion yields. Mannitol dehydrogenase was purified and characterized; it had the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4bc2c3e37ef87efc2d02651ea9d758
https://doi.org/10.1023/a:1023512218206
https://doi.org/10.1023/a:1023512218206