Výsledky vyhledávání - "Hyung-Geun Moon"

Akademický článek

Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling

Autor: Young-Mee Kim, Sarah Krantz, Ankit Jambusaria, Peter T. Toth, Hyung-Geun Moon, Isuru Gunarathna, Gye Young Park, Jalees Rehman

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Endothelial tissues must have intact barrier function, but this may be disrupted during inflammation. Here, the authors show that the mitochondrial protein Mitofusin-2 stabilizes cell–cell adherens junctions in endothelial cells during homeostasis

Externí odkaz: https://doaj.org/article/e5953cf98299418595f144ad5dbc7489

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Akademický článek

MicroRNA-15a/16 Regulates Apoptosis of Lung Epithelial Cells After Oxidative Stress

Autor: Yong Cao, Duo Zhang, Hyung-Geun Moon, Heedoo Lee, Jeffrey A Haspel, Kebin Hu, Lixin Xie, Yang Jin

Publikováno v: Molecular Medicine, Vol 22, Iss 1, Pp 233-243 (2016)

Abstract Lung epithelial cell apoptosis is an important feature of hyperoxia-induced lung injury. The death receptor-associated extrinsic pathway and mitochondria-associated intrinsic pathway both mediate the development of lung epithelial cell apopt

Externí odkaz: https://doaj.org/article/beef18779df4449182ecd3e923818496

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Akademický článek

Flotillin-2 modulates fas signaling mediated apoptosis after hyperoxia in lung epithelial cells.

Autor: Shuquan Wei, Hyung-Geun Moon, Yijie Zheng, Xiaoliang Liang, Chang Hyeok An, Yang Jin

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77519 (2013)

Lipid rafts are subdomains of the cell membrane with distinct protein composition and high concentrations of cholesterol and glycosphingolipids. Raft proteins are thought to mediate diverse cellular processes including signal transduction. However, i

Externí odkaz: https://doaj.org/article/f85118bda737487d873205e97394323a

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Akademický článek

Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the progression of dextran sulfate sodium-induced colitis.

Autor: Chil-Sung Kang, Mingi Ban, Eun-Jeong Choi, Hyung-Geun Moon, Jun-Sung Jeon, Dae-Kyum Kim, Soo-Kyung Park, Seong Gyu Jeon, Tae-Young Roh, Seung-Jae Myung, Yong Song Gho, Jae Gyu Kim, Yoon-Keun Kim

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76520 (2013)

Gut microbiota play an important part in the pathogenesis of mucosal inflammation, such as inflammatory bowel disease (IBD). However, owing to the complexity of the gut microbiota, our understanding of the roles of commensal and pathogenic bacteria i

Externí odkaz: https://doaj.org/article/a34523c49cc44ab790722fb7ce164199

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Akademický článek

CCN1 secretion induced by cigarette smoking extracts augments IL-8 release from bronchial epithelial cells.

Autor: Hyung-Geun Moon, Yijie Zheng, Chang Hyeok An, Yoon-Keun Kim, Yang Jin

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68199 (2013)

Inflammation involves in many cigarette smoke (CS) related diseases including the chronic obstructive pulmonary disease (COPD). Lung epithelial cell released IL-8 plays a crucial role in CS induced lung inflammation. CS and cigarette smoke extracts (

Externí odkaz: https://doaj.org/article/56f3a2fe56e8428490016cff543622a5

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Akademický článek

Therapeutic effects of autologous tumor-derived nanovesicles on melanoma growth and metastasis.

Autor: Eun-Young Lee, Kyong-Su Park, Yae Jin Yoon, Jaewook Lee, Hyung-Geun Moon, Su Chul Jang, Kyoung-Ho Choi, Yoon-Keun Kim, Yong Song Gho

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33330 (2012)

Cancer vaccines with optimal tumor-associated antigens show promise for anti-tumor immunotherapy. Recently, nano-sized vesicles, such as exosomes derived from tumors, were suggested as potential antigen candidates, although the total yield of exosome

Externí odkaz: https://doaj.org/article/982a3fe8147147e191e726c1cdaf651e

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