Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hyung-Doo Shin"'
Autor:
Joong-Gon Shin, Jee Wook Kim, Ihn-Geun Choi, Byung Lae Park, Young Min Choe, Hyung-Doo Shin, Boung Chul Lee
Publikováno v:
Neuropsychiatric Disease and Treatment. 15:83-94
Background Alcohol dependence (AD) is a common disorder that is influenced by genetic as well as environmental factors. A previous genome-wide association study (GWAS) of the Korean population performed by our research group identified a number of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ccc60cfc600b7085b22fa4d749b072
https://doi.org/10.2147/ndt.s184067
https://doi.org/10.2147/ndt.s184067
Autor:
Jee Wook, Kim, Young Min, Choe, Joong-Gon, Shin, Byung Lae, Park, Hyung-Doo, Shin, Ihn-Geun, Choi, Boung Chul, Lee
Publikováno v:
Neuropsychiatric Disease and Treatment
Background Alcohol dependence (AD) is a common disorder that is influenced by genetic as well as environmental factors. A previous genome-wide association study (GWAS) of the Korean population performed by our research group identified a number of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1fba3eb310ad840733fd99c8e9e23b8
https://pubmed.ncbi.nlm.nih.gov/30636874
https://pubmed.ncbi.nlm.nih.gov/30636874
Autor:
Inseon S. Choi, B L Park, J.S. Park, Seung-Woo Shin, Tae-Hyeong Lee, Da-Jeong Bae, C. S. Park, Hyung Doo Shin, Yong Hoon Kim, Soo-Taek Uh, Byoung Whui Choi, M-K Kim, Hun-Soo Chang
Publikováno v:
The Pharmacogenomics Journal. 15:316-321
We developed a genetic marker set of single nucleotide polymorphisms (SNPs) by summing risk scores of 14 SNPs showing a significant association with aspirin-exacerbated respiratory disease (AERD) from our previous 660 W genome-wide association data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb217a1d499c177fe98f23b0278e55fb
https://doi.org/10.1038/tpj.2014.78
https://doi.org/10.1038/tpj.2014.78
Autor:
Sang-Hyuk Yoon, Jae Sung Choi, Ji-Yeon Cha, Tae Hoon Kim, Ji-Yeon Lee, Eun-Kyong Shin, Soo-Taek Uh, Young Mok Lee, Soo-Ok Lee, Choon-Sik Park, Byung-Lae Park, Hyung-Doo Shin, Young Hoon Kim, Jong-Sook Park, Sung-Hye An, Sung Woo Park
Publikováno v:
Respirology. 16:630-638
Background and objective: The neurotransmitter, 5-hydroxytryptamine, acts as an immunomodulator by stimulating the release of inflammatory cytokines and regulating the function of dendritic cells and monocytes. The 5-hydroxytryptamine receptor 4 (HTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5c05fa56b6aeb2e9713ce7e8c87951
https://doi.org/10.1111/j.1440-1843.2011.01963.x
https://doi.org/10.1111/j.1440-1843.2011.01963.x
Autor:
Sung Woo Park, Choon-Sik Park, Jong-Keuk Lee, Hun Soo Chang, An-Soo Jang, Bermseok Oh, Yong Hoon Kim, Kuchan Kimm, Shin-Hwa Lee, Jong Sook Park, Soo-Taek Uh, Byung-Lae Park, Hyung Doo Shin
Publikováno v:
Annals of Human Genetics. 75:359-369
Summary Asthma manifests as TH2-dominant airway inflammation regulated by inducible T-cell kinase (ITK). To investigate associations between genetic variants of the ITK gene and asthma, 31 single-nucleotide polymorphisms (SNPs) were genotyped in 303
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51889890d00ed9cadd3d1f524a02fc41
https://doi.org/10.1111/j.1469-1809.2010.00637.x
https://doi.org/10.1111/j.1469-1809.2010.00637.x
Autor:
Se-Min Park, Hun-Soo Chang, Il Yup Chung, Hun-Gyu Hwang, Choon-Sik Park, Ju Ock Na, Soo-Taek Uh, Yong Hoon Kim, Sung Woo Park, An Soo Jang, Jong Sook Park, Hyung Doo Shin, Mi Young Lee, Byung Lae Park, Taiyoun Rhim
Publikováno v:
Human Immunology. 71:1147-1153
Nuclear factor-κB (NF-κB) orchestrates the expression of genes responsible for airway inflammation and remodeling in asthma. The activity of NF-κB is tightly regulated by IKBA, which may be modulated by genetic polymorphisms of the IKBA gene. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d25cae139aafe88fdaa4c0469b27c2
https://doi.org/10.1016/j.humimm.2010.07.002
https://doi.org/10.1016/j.humimm.2010.07.002
Autor:
Sungha Park, Bok Ghee Han, Jong-Keuk Lee, Jong-Young Lee, Ha Jung Ryu, Hung Tae Kim, Seung Hun Cha, Hyung Doo Shin, Jun Woo Kim, Kuchan Kimm, Bermseok Oh, Byung Lae Park, Yangsoo Jang, Hyun Young Park
Publikováno v:
Clinica Chimica Acta. 382:129-133
Coronary artery disease (CAD) is one of the most common forms of heart disease. It has been demonstrated that chemokine-mediated inflammation is associated with the development of CAD. In this study, in order to determine the role of CCR2, a receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b436df1123add9cd28a7078ffc716bc7
https://doi.org/10.1016/j.cca.2007.03.017
https://doi.org/10.1016/j.cca.2007.03.017
Autor:
Choon-Sik Park, Hyo-Bin Kim, Mi-Jin Kang, Soo-Jong Hong, Ja-Hyung Kim, Seong-Ok Jang, Hyung-Doo Shin, Bong Seong Kim, So-Yeon Lee
Publikováno v:
Journal of Allergy and Clinical Immunology. 119:398-404
Background TNF-α is a pivotal proinflammatory cytokine increased in asthmatic airways. The TNF-α gene family might be linked to asthma or bronchial hyperresponsiveness (BHR), and TNF-α production might be modulated by CD14 + cells. Objective We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef362461fbf87296e7c4d55c4dd1cb9
https://doi.org/10.1016/j.jaci.2006.10.031
https://doi.org/10.1016/j.jaci.2006.10.031
Autor:
Hun Soo Chang, Jeong-Seok Heo, Seung-Woo Shin, Da-Jeong Bae, Hyun Ji Song, Ji Ae Jun, Jeong Dong Kim, Jong-Sook Park, Byung Lae Park, Hyung Doo Shin, Choon-Sik Park
Publikováno v:
Pharmacogenetics and genomics. 25(7)
Genetic polymorphisms may be responsible for the wide variation in response to inhaled corticosteroids in asthmatic patients. We had previously reported that one polymorphism rs7772821, located on the 3'-UTR of trace amine-associated receptor 6 (TAAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35b65817a211c2a1da4a67e336c09c6
https://pubmed.ncbi.nlm.nih.gov/25919112
https://pubmed.ncbi.nlm.nih.gov/25919112
Publikováno v:
Reproduction, Fertility and Development. 30:167
Sirtuin (Sirt), nicotinamide adenine dinucleotide dependent class III histone deacetylase, plays an important role in cellular processes including DNA repair, apoptosis, cell cycle, aging, and determining lifespan. In previous studies, levels of Sirt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b81bec6b5e41f04ac48e1aff97bea0
https://doi.org/10.1071/rdv30n1ab56
https://doi.org/10.1071/rdv30n1ab56