Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hyung-Bae MOON"'
Autor:
Ji-Su Mo, Suck-Chei Choi, Hun-Soo Kim, Hyung-Bae Moon, Geom-Seog Seo, In-Hong Kang, Won Cheol Park, Ki-Jung Yun, Khondoker Jahengir Alam, Soo-Cheon Chae
Publikováno v:
Oncotarget
Using miRNA microarray analysis, we identified 31 miRNAs that were significantly up-regulated or down-regulated in colon cancer tissues. We chose MIR196B, which was specifically up-regulated in colon cancer, for further study. We identified 18 putati
Publikováno v:
Genes & Genomics. 34:77-82
Human thymic stromal lymphopoietin receptor (TSLPR) was identified from T lymphocytes and dendritic cells, and is believed to play an important role in the development of inflammatory and allergic responses. We previously identified 11 single-nucleot
Autor:
Hong Young Jun, Seong Hoon Park, Sun-Uk Kim, Dae-Yeul Yu, Hyung-Bae Moon, Dong-Ho Bang, Kwon-Ha Yoon
Publikováno v:
Academic Radiology. 18:13-19
Rationale and Objectives The aims of this study were to evaluate the morphologic characteristics and growth pattern of hepatic tumors in H- ras 12V transgenic (TG) mice using a micro–magnetic resonance (MR) system and to assess the usefulness of ga
Autor:
Yeon-Weol Lee, Chong-Kwan Cho, Hyung-Bae Moon, Hwa-Seung Yoo, Hye-Lin Ha, Dae-Yeul Yu, Jung-Sun Kim
Publikováno v:
Integrative Cancer Therapies. 10:168-177
Unlike other forms of hepatocellular carcinoma (HCC), HCC induced by hepatitis B virus (HBV) infection shows a poor prognosis after conventional therapies. HBV induces liver cirrhosis and HCC. Many researchers have made efforts to find new substances
Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice
Autor:
Jin Man Kim, Soon B. Hwang, Kyung-Hyun Cho, Ying-Hao Han, Dae-Ghon Kim, Hye-Lin Ha, Dae-Yeul Yu, Soo-Ho Choi, Ai-Guo Wang, Hyung-Bae Moon, Dong-Seok Lee
Publikováno v:
The Journal of Pathology. 219:253-262
Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). However, the mechanism of HCV pathogenesis is not well understood. Our previous in vitro studies suggested that non-structural 5A (NS5A
Autor:
Soo-Cheon Chae, Hun-Soo Kim, Jae-Hoon Lee, Hyung-Bae Moon, Ji-In Yu, Ki-Jung Yun, Weon-Cheol Han
Publikováno v:
Journal of Life Science. 19:299-304
Interleukin 27 (IL-27) was discovered as a heterodimeric cytokine of the IL-12 family, and is composed of two subunits - Epstein-Barr virus induced gene 3 (EBI3) and p28. It acts as a versatile cytokine in the early regulation of Th1 initiation and i
Autor:
Soo-Cheon Chae, Shin-Seok Lee, Hyung-Bae Moon, Qinggao Zhang, Chun-Shi Li, Mi-Kyoung Lim, Ji-Young Kim, Hun-Taeg Chung, Seung-Cheol Shim, Ki-Jung Yun, Dong-Hyuk Sheen
Publikováno v:
Experimental & Molecular Medicine. 39:805-811
The forkhead-box J1 (FOXJ1) transcription factor could suppress a spontaneous activation of T cells and B cells through an induction of IkappaBbeta that results in repression of NF-kappaB activity. In Foxj1 deficiency mice, systemic autoimmune inflam
Publikováno v:
Life Sciences. 79:1974-1980
A common characteristic of hepatocellular carcinoma in humans and animals is a striking male prevalence. However, the underlying mechanisms remain largely unknown. We have reported that hepatotumorigenesis is prevalent in male H-ras12V transgenic mic
Autor:
Byung-Hwa Hyun, Hyung-Bae Moon, Sun-Uk Kim, Dae-Yeul Yu, Ai-Guo Wang, Nam-Soon Kim, Dong-Seok Lee, Jun-Gyo Suh, Ki-Hoan Nam
Publikováno v:
Journal of Life Science. 16:566-570
Pronuclear microinjection (PMI) is a primary method for producing transgenic mice and offers a powerful tool for investigating gene function in vivo. The method has several reported advantages and disadvantages. Here, we report another potential shor
Autor:
B. Hwa SOHN, Hyung-Bae MOON, Tae-Yoon KIM, Han-Sung KANG, Yoon Soo BAE, Kyung-Kwang LEE, Sun Jung KIM
Publikováno v:
Biochemical Journal. 360:31-38
Although interleukin-10 (IL-10) is known to contribute to inflammation and pathogenesis in mammalian organs, little is known about its precise role in the mammary gland. We found that IL-10 levels fluctuated during the mouse mammary cycle, showing li