Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Hyung Ho Lee"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract GPR179, an orphan class C GPCR, is expressed at the dendritic tips of ON-bipolar cells in the retina. It plays a pivotal role in the initial synaptic transmission of visual signals from photoreceptors, and its deficiency is known to be the c
Externí odkaz:
https://doaj.org/article/ca13d606515a4ab1bc80d45a2c05c76a
Autor:
Suk Min Kim, Sung Heuck Kang, Jinhee Lee, Yoonyoung Heo, Eleni G. Poloniataki, Jingu Kang, Hye-Jin Yoon, So Yeon Kong, Yaejin Yun, Hyunwoo Kim, Jungki Ryu, Hyung Ho Lee, Yong Hwan Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Fe‒S cluster-harboring enzymes, such as carbon monoxide dehydrogenases (CODH), employ sophisticated artificial electron mediators like viologens to serve as potent biocatalysts capable of cleaning-up industrial off-gases at stunning reacti
Externí odkaz:
https://doaj.org/article/64c19e8a4f2a4362a0d29cf896a48375
Autor:
Junsun Park, Yoonyoung Heo, Byoung Wook Jeon, Mingyu Jung, Yong Hwan Kim, Hyung Ho Lee, Soung-Hun Roh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Formate dehydrogenase (FDH) is critical for the conversion between formate and carbon dioxide. Despite its importance, the structural complexity of FDH and difficulties in the production of the enzyme have made elucidating its unique physico
Externí odkaz:
https://doaj.org/article/13fbb453ce124be689cf88f93e4ae748
Autor:
Joongwon Choi, Seokhwan Bang, Jungyo Suh, Chang Il Choi, Wan Song, Hyeong Dong Yuk, Chan Ho Lee, Minyong Kang, Seol Ho Choo, Jung Kwon Kim, Hyung Ho Lee, Jung Ki Jo, Eu Chang Hwang, Chang Wook Jeong, Young Hwii Ko, Jae Young Park, Cheryn Song, Seong Il Seo, Jinsoo Chung, Cheol Kwak, Sung-Hoo Hong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The World Health Organization/International Society of Urological Pathology (WHO/ISUP) grading of renal cell carcinoma (RCC) is classified from grade 1–4, regardless of subtype. The National Comprehensive Cancer Network (NCCN) guidelines (
Externí odkaz:
https://doaj.org/article/a17fdbb423f64978a41bbf08ce13ca40
Publikováno v:
Journal of CO2 Utilization, Vol 82, Iss , Pp 102754- (2024)
This study introduces a novel approach for CO2 reduction to formate using the recombinant formate dehydrogenase 1 (MeFDH1) from Methylorubrum extorquens AM1 as biocatalyst, addressing challenges in activity, productivity, and long-term stability of e
Externí odkaz:
https://doaj.org/article/96350412135842e1a26cd818c668fef9
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Transient receptor potential vanilloid member 3 (TRPV3) is an ion channel that plays a critical role in temperature sensing in skin. There have been active studies on how TRPV3, which is also known as one of the temperature-sensitive transie
Externí odkaz:
https://doaj.org/article/4e10289701d94719a8c16dc708d048ac
Autor:
Jongdae Won, Jinsung Kim, Hyeongseop Jeong, Jinhyeong Kim, Shasha Feng, Byeongseok Jeong, Misun Kwak, Juyeon Ko, Wonpil Im, Insuk So, Hyung Ho Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract G-protein coupled receptors (GPCRs) and ion channels serve as key molecular switches through which extracellular stimuli are transformed into intracellular effects, and it has long been postulated that ion channels are direct effector molecu
Externí odkaz:
https://doaj.org/article/8e6d548a17d64ee88281a7d6e6b05ebe
Autor:
Seu-Na Lee, Hwa-Jin Cho, Hyeongseop Jeong, Bumhan Ryu, Hyuk-Joon Lee, Minsoo Kim, Jejoong Yoo, Jae-Sung Woo, Hyung Ho Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Connexin 36 (Cx36) gap junction channel is responsible for signal transmission in electrical synapses. Here, the authors determine cryo-EM structures of Cx36, providing insights into a potential role of lipids in the channel gating.
Externí odkaz:
https://doaj.org/article/be34f9ad35c84967aec756611a123668
Autor:
Ji Hyun Kim, Dong-eun Lee, Hyeong In Ha, Jae Young Jung, Sung Han Kim, Hyung Ho Lee, Ho Kyung Seo, Sang-Soo Seo, Sokbom Kang, Sang-Yoon Park, Myong Cheol Lim
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Ureteral reconstruction is required after surgical resection of the tumor invading the urinary tract in ovarian cancer with low incidence. There are no currently reported surgical outcomes of ureteral reconstruction during cytored
Externí odkaz:
https://doaj.org/article/8943a8bf0a80475e8cf03d345540f230
Autor:
Mingyu Kim, Hyung Ho Lee, So Dam Won, YeonSue Jang, Baek Gil Kim, Nam Hoon Cho, Young Deuk Choi, Jin Soo Chung, Hyun Ho Han
Publikováno v:
Medicina, Vol 60, Iss 1, p 181 (2024)
ERBB3, a key member of the receptor tyrosine kinase family, is implicated in the progression and development of various human cancers, affecting cellular proliferation and survival. This study investigated the expression of ERBB3 isoforms in renal cl
Externí odkaz:
https://doaj.org/article/13665321573342e4bb02061eb54ae68c