Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hyung Gyoo Kang"'
Autor:
Poul H.B. Sorensen, Timothy J. Triche, C. Patrick Reynolds, Xian Fang Liu, Jasmine M. Jenabi, Hyung-Gyoo Kang
The insulin-like growth factor I receptor (IGFIR) has emerged as a key therapeutic target in many human malignancies, including childhood cancers such as Ewing family tumors (EFT). In this study, we show that IGFIR is constitutively activated in EFTs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce931bd67b976aa5bf5214e26d5c77a
https://doi.org/10.1158/1535-7163.c.6532016.v1
https://doi.org/10.1158/1535-7163.c.6532016.v1
Autor:
Poul H.B. Sorensen, Timothy J. Triche, C. Patrick Reynolds, Tony Ng, William A. May, Hiroyuki Shimada, Nino Keshelava, Jingsong Zhang, Jasmine M. Jenabi, Hyung-Gyoo Kang
Supplementary Figures 1-4 from E-Cadherin Cell-Cell Adhesion in Ewing Tumor Cells Mediates Suppression of Anoikis through Activation of the ErbB4 Tyrosine Kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166494c4a35328e57fdf5a8215435589
https://doi.org/10.1158/0008-5472.22366814
https://doi.org/10.1158/0008-5472.22366814
Autor:
Poul H.B. Sorensen, Timothy J. Triche, C. Patrick Reynolds, Tony Ng, William A. May, Hiroyuki Shimada, Nino Keshelava, Jingsong Zhang, Jasmine M. Jenabi, Hyung-Gyoo Kang
Supplementary Figure Legends 1-4 from E-Cadherin Cell-Cell Adhesion in Ewing Tumor Cells Mediates Suppression of Anoikis through Activation of the ErbB4 Tyrosine Kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6321a3eb5c6c8687bd5b64c2e0240806
https://doi.org/10.1158/0008-5472.22366817.v1
https://doi.org/10.1158/0008-5472.22366817.v1
Autor:
Poul H.B. Sorensen, Timothy J. Triche, C. Patrick Reynolds, Tony Ng, William A. May, Hiroyuki Shimada, Nino Keshelava, Jingsong Zhang, Jasmine M. Jenabi, Hyung-Gyoo Kang
Ability to grow under anchorage-independent conditions is one of the major hallmarks of transformed cells. Key to this is the capacity of cells to suppress anoikis, or programmed cell death induced by detachment from the extracellular matrix. To mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ecfb18a3ef04327f61d2ab875eccac
https://doi.org/10.1158/0008-5472.c.6495305.v1
https://doi.org/10.1158/0008-5472.c.6495305.v1
Autor:
Jay Joo, Laura Christensen, Kegan Warner, Leith States, Hyung-Gyoo Kang, Kieuhoa Vo, Elizabeth R Lawlor, William A May
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7608 (2009)
The Ewing Sarcoma Family Tumors (ESFT) consist of the classical pathologic entities of Ewing Sarcoma and peripheral Primitive Neuroectodermal Tumor. Occurring largely in the childhood through young adult years, these tumors have an unsurpassed propen
Externí odkaz:
https://doaj.org/article/83da810e68f847d1ba15f7787b7c0a62
Publikováno v:
Cancer Research. 80:1717-1717
Current cancer therapy relies on the use of cytotoxic agents (‘chemotherapy') that was developed over 50 years ago. These agents are very effective, but efficacy is limited by off-target toxicity to normal tissues. It is widely recognized that chem
Publikováno v:
Cell Biology International. 38:531-537
Human amniotic fluid stem cells (HAFSCs) have a high proliferative capacity and a good differentiation potential, and may thus be suitable for regenerative medicine. To date, urothelial differentiation mechanisms of HAFSCs are poorly understood. We h
Publikováno v:
Cancer Research. 79:2875-2875
Most anticancer therapies are unspecific and therefore inevitably lead to off-target toxicity. To overcome these shortcomings, targetable hybrid polymerization liposomal nanoparticles (HPLNs) have been invented. Multiple innovative and proprietary te
Publikováno v:
Cancer Research. 78:402-402
Gene editing tools like CRISPR, using Cas9 protein and selected guide RNAs, are now the preferred method to study many coding gene functions, but historically have been hampered by low efficiency (typically 2,000 targets in common based on total RNA
Publikováno v:
Cancer Research. 78:3705-3705
Most anticancer therapies are unspecific and therefore inevitably lead to off-target toxicity. To overcome these shortcomings, targetable hybrid polymerization liposomal nanoparticles (HPLNs) have been invented. Multiple innovative and proprietary te