Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Hyunbae Kim"'
Autor:
Manya Warrier, Evan M. Paules, Jorge Silva-Gomez, Walter B. Friday, Frances Bramlett, Hyunbae Kim, Kezhong Zhang, Isis Trujillo-Gonzalez
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13216- (2023)
Betaine-homocysteine methyltransferase (BHMT) catalyzes the transfer of methyl groups from betaine to homocysteine (Hcy), producing methionine and dimethylglycine. In this work, we characterize Bhmt wild type (Bhmt-WT) and knockout (Bhmt-KO) mice tha
Externí odkaz:
https://doaj.org/article/48c9e4f42f324737bf9f765e4c44d85e
Autor:
Hyunbae Kim, Zhiyao Fu, Zhao Yang, Zhenfeng Song, El Hussain Shamsa, Thangal Yumnamcha, Shengyi Sun, Wanqing Liu, Ahmed S. Ibrahim, Nathan R. Qi, Ren Zhang, Kezhong Zhang
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101562- (2022)
Objective: The mitochondrial nicotinamide adenine dinucleotide (NAD) kinase (MNADK) mediates de novo mitochondrial NADP biosynthesis by catalyzing the phosphorylation of NAD to yield NADP. In this study, we investigated the function and mechanistic b
Externí odkaz:
https://doaj.org/article/c85b88a37ce64fe187b3ad631e709899
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 8, p e0000707 (2022)
Air pollutants, particularly airborne particulate matter with aerodynamic diameter < 2.5μm (PM2.5), have been linked to the increase in mortality and morbidity associated with cardiovascular and metabolic diseases. In this study, we investigated the
Externí odkaz:
https://doaj.org/article/0f2df32ed3944eeb87cfa50c32a5c14c
Autor:
Yanbo Fan, Brooke N. Wolford, Haocheng Lu, Wenying Liang, Jinjian Sun, Wei Zhou, Oren Rom, Anubha Mahajan, Ida Surakka, Sarah E. Graham, Zhipeng Liu, Hyunbae Kim, Shweta Ramdas, Lars G. Fritsche, Jonas B. Nielsen, Maiken Elvestad Gabrielsen, Kristian Hveem, Dongshan Yang, Jun Song, Minerva T. Garcia-Barrio, Jifeng Zhang, Wanqing Liu, Kezhong Zhang, Cristen J. Willer, Y. Eugene Chen
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103196- (2021)
Summary: The rs58542926C >T (E167K) variant of the transmembrane 6 superfamily member 2 gene (TM6SF2) is associated with increased risks for nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). Nevertheless, the role of the TM6SF2 rs58
Externí odkaz:
https://doaj.org/article/123d0eb5291545f598be4e64a51063ec
Autor:
Hyunbae Kim, Juncheng Wei, Zhenfeng Song, Emilio Mottillo, Lobelia Samavati, Ren Zhang, Li Li, Xuequn Chen, Bhanu P. Jena, Jiandie D. Lin, Deyu Fang, Kezhong Zhang
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101192- (2021)
Objective: The endoplasmic reticulum (ER)-resident E3 ligase HRD1 and its co-activator Sel1L are major components of ER-associated degradation (ERAD) machinery. Here, we investigated the molecular mechanism and functional significance underlying the
Externí odkaz:
https://doaj.org/article/03763536f0bc4c2ea0146ac011ff1430
Autor:
Kezhong Zhang, Hui Liu, Zhenfeng Song, Yuanyuan Jiang, Hyunbae Kim, Lobelia Samavati, Hien M. Nguyen, Zeng-Quan Yang
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101503- (2020)
Summary: Dysregulation of inositol-requiring enzyme 1 (IRE1), the primary transducer of Unfolded Protein Response (UPR), has been observed in tumor initiation and progression, but the underlying mechanism remains to be further elucidated. In this stu
Externí odkaz:
https://doaj.org/article/08ec9167b7124705ab350fe9a629e9c7
Publikováno v:
Applied Sciences, Vol 11, Iss 21, p 10321 (2021)
Aquifer thermal energy storage (ATES) system is widely used mainly in Europe and USA. In this paper, we examined the efficient operation method of ATES by comparing it with the water thermal energy storage (WTES) system of an existent thermal energy
Externí odkaz:
https://doaj.org/article/06c4e38f59594f959a85f74e9e76f7de
Publikováno v:
Liver Research, Vol 1, Iss 3, Pp 156-162 (2017)
Circadian rhythms play crucial roles in orchestrating diverse physiological processes that are critical for health and disease. Dysregulated circadian rhythms are closely associated with various human metabolic diseases, including type 2 diabetes, ca
Externí odkaz:
https://doaj.org/article/cdf6fab9d1f64959a062067cafe51e1d
Publikováno v:
Energies, Vol 14, Iss 11, p 3129 (2021)
The mass introduction of renewable energy is essential to reduce carbon dioxide emissions. We examined an operation method that combines the surplus energy of photovoltaic power generation using demand response (DR), which recognizes the balance betw
Externí odkaz:
https://doaj.org/article/0deffb5d5fd7461092295c1c29f9706f
Publikováno v:
IEEE Journal of Emerging and Selected Topics in Power Electronics. 10:1353-1362