Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hyunah L. Yoon"'
Publikováno v:
Molecular Carcinogenesis. 20:48-57
SSIN mice are very sensitive to tumor promoters in two-stage skin carcinogenesis protocols. It was recently reported that SSIN mice have fewer CD8+ T-cells than other strains of mice and develop a weaker cytotoxic T-cell response upon challenge with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::addb05909afa2ab0313b3c7bbae8ed56
https://doi.org/10.1002/(sici)1098-2744(199709)20:1<48::aid-mc6>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199709)20:1<48::aid-mc6>3.0.co
Publikováno v:
Toxicological Sciences. 33:129-139
The effects of topically applied 12-O-tetradecanoylphorbol-13-acetate (TPA), acetone, and ethanol on systemic immune function were analyzed in SSIN mice. A total of one, four, or eight dorsal applications of solvent (50-300 microl/treatment, 2x/week)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69415a3b9904cc81d13f4d1aa4094312
https://doi.org/10.1093/toxsci/33.1.129
https://doi.org/10.1093/toxsci/33.1.129
Publikováno v:
Carcinogenesis. 17:2617-2624
SSIN mice are considerably more sensitive to the effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in two-stage skin carcinogenesis protocols than are most other strains and stocks of mice. Experiments were performed to determine whether there wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26c8addafd59056214999ba9411cd20
https://doi.org/10.1093/carcin/17.12.2617
https://doi.org/10.1093/carcin/17.12.2617
Publikováno v:
Toxicology and Applied Pharmacology. 109:375-390
3-Methylindole (3-MI) is a pneumotoxic metabolite of L-tryptophan that can form in the digestive tracts of humans and ruminants as a result of microbial protein metabolism. Alternatively, human lungs can be directly exposed to 3-MI formed during prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb8faf9b0ac274db5066a09e79361a1
https://doi.org/10.1016/0041-008x(91)90001-u
https://doi.org/10.1016/0041-008x(91)90001-u
Publikováno v:
Toxicology and Applied Pharmacology. 109:391-398
In this laboratory, 3-methylindole (3-MI), a pneumotoxic metabolite of L-tryptophan that forms in the digestive tract of humans and ruminants, has been demonstrated to be toxic to rat and mouse splenic cells both in vitro and in vivo. The present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc726b5052f9e7c6036f1a6e4d64cf8f
https://doi.org/10.1016/0041-008x(91)90002-v
https://doi.org/10.1016/0041-008x(91)90002-v
Publikováno v:
Molecular carcinogenesis. 7(2)
Local production of reactive oxygen intermediates, e.g., superoxide anion, by tumor promoter-stimulated inflammatory macrophages (MPs) may contribute significantly to tumor development in classical models of two-stage chemical-induced carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8656b0f27990cbbb2f3cec8b4bc8070
https://pubmed.ncbi.nlm.nih.gov/8384457
https://pubmed.ncbi.nlm.nih.gov/8384457
Publikováno v:
Carcinogenesis. 12(4)
Previous studies in this laboratory and others have indicated that 12-O-tetradecanoylphorbol-13-acetate (TPA), the most potent skin tumor promoter known, evokes significantly greater inflammatory responses in phorbol ester-sensitive (SENCAR) mice com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ae3a47443050dc1bab57fb5c955599
https://pubmed.ncbi.nlm.nih.gov/2013137
https://pubmed.ncbi.nlm.nih.gov/2013137
Autor:
Anchalee Chuthaputti, Richard W. Pfeifer, George K.W. Yim, Hyunah L. Yoon, Lawrence W. Updyke
Publikováno v:
Carcinogenesis. 10(6)
12-O-tetradecanoylphorbol-13-acetate (TPA), the most potent skin tumor promoter known, evokes significant inflammatory responses in mouse skin after topical application. Infiltrating inflammatory cells have been hypothesized to contribute to genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17a6b24719d662c780a0fd8fc34ed5e
https://pubmed.ncbi.nlm.nih.gov/2785869
https://pubmed.ncbi.nlm.nih.gov/2785869
Autor:
Hyunah L. Yoon, Lawrence W. Updyke, Richard W. Pfeifer, Anchalee Chuthaputti, George K.W. Yim
Publikováno v:
Immunopharmacology and immunotoxicology. 11(4)
Following topical application of 8 micrograms 12-O-tetradecanoylphorbol-13-acetate (TPA) twice in one week, the ability of splenic macrophages (M phi s) isolated from phorbol ester-sensitive (SENCAR) and resistant (B6C3F1) mice to suppress the phytoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112d45df9bab28bb2adfcc0b54bb3cc4
https://pubmed.ncbi.nlm.nih.gov/2628481
https://pubmed.ncbi.nlm.nih.gov/2628481