Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Hyun-Woo Yang"'
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 17, Iss 2, Pp 147-159 (2024)
Objectives. Air pollution is an increasing global concern, and its effect on allergic inflammation has attracted the attention of many researchers. Particulate matter (PM) is a major component of ambient air pollution, and heavy metals are the primar
Externí odkaz:
https://doaj.org/article/cb7a9bf2d1544a90b54aff49dd4a6d66
Autor:
Hyun-Woo Yang, Joo-Hoo Park, Jae-Min Shin, Hyeong-Guk Son, Tae-Hoon Kim, Seung-Hoon Lee, Il-Ho Park
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundChronic rhinosinusitis (CRS) is an inflammatory disease affecting more than 10% of the global adult population. It is classified into Th1, Th2, and Th17 endotypes and eosinophilic and non-eosinophilic types. Th2-based inflammation and eosin
Externí odkaz:
https://doaj.org/article/c3fcb18d50294f00a13a2b6aa922be11
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Background Adipose tissue is known to serve as an abundant and readily accessible source of adipose-derived stem cells (ADSCs) as an alternative to bone marrow. Collagenase is one of the most widely used methods for the isolation of ADSCs fr
Externí odkaz:
https://doaj.org/article/0402351db62645d7a71d9e26a56b3d68
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0285655 (2024)
BackgroundChronic rhinosinusitis (CRS) is an inflammatory disease affecting the sinuses or nose. Persistent inflammatory responses can lead to tissue remodeling, which is a pathological characteristics of CRS. Activation of fibroblasts in the nasal m
Externí odkaz:
https://doaj.org/article/5536fcea562a4ca2bdfa91de2fa1832b
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Background Glycolytic reprogramming is a key feature of chronic inflammatory disease. Extracellular matrix (ECM) produced by myofibroblasts plays an important role in tissue remodeling of nasal mucosa in chronic rhinosinusitis (CRS). This study aimed
Externí odkaz:
https://doaj.org/article/7ee4f03e53b14c35905ddd736e49fbab
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundEosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis (CRS) and is a refractory or intractable disease. However, a reliable clinical marker or an effective treatment strategy has not yet been established. ECRS is
Externí odkaz:
https://doaj.org/article/2c959001fc5448fc8dc40a0fc34abdbf
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3003 (2022)
Chronic rhinosinusitis (CRS) pathogenesis is closely related to tissue remodeling, including epithelial–mesenchymal transition (EMT). Epigenetic mechanisms play key roles in EMT. DNA methylation, mediated by DNA methyltransferases (DNMTs), is an ep
Externí odkaz:
https://doaj.org/article/39bd0badf2f949fab44c316ef7ea1047
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11535 (2021)
Tissue remodeling contributes to ongoing inflammation and refractoriness of chronic rhinosinusitis (CRS). During this process, epithelial-mesenchymal transition (EMT) plays an important role in dysregulated remodeling and both microRNA (miR)-29b and
Externí odkaz:
https://doaj.org/article/19782d895def4032b7cd9359a14060fc
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract To investigate the potential role of vitamin D (1,25(OH)2D3) in preventing the development of nasal polyps, we examined the effect of vitamin D on myofibroblast differentiation and extracellular matrix (ECM) production in TGF-β1-induced nas
Externí odkaz:
https://doaj.org/article/11559d6f25224c8a808047db444ec411
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of
Externí odkaz:
https://doaj.org/article/fa34d5da0d1e4e9faa599e4f6c51b888