Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hyun-Tae Shin"'
Autor:
Jun Hyeok Lim, Hyun-Tae Shin, Sunmin Park, Woo Kyung Ryu, Lucia Kim, Kyung-Hee Lee, Sung Min Ko, Seung Jae Lee, Jung Soo Kim, Jeong-Seon Ryu
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102134- (2024)
Background: Early-stage lung cancers detected by low-dose computed tomography (CT) often require confirmation through invasive procedures due to the absence of endobronchial lesions. This study assesses the diagnostic utility of bronchial washing flu
Externí odkaz:
https://doaj.org/article/3b78ba7f30c84223904b12862dd5e797
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Background The prevalence of open-angle glaucoma (OAG) varies from 0.5% to 7.0% among populations of diverse ancestry, suggesting the existence of genetic differences. The purposes of this study were to provide insights into genetic causes o
Externí odkaz:
https://doaj.org/article/5bf6d88437bf46e9bc74faa3d4c5e916
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background The prevalence of age-related macular degeneration (AMD) varies from 6.8 to 18.3% for all forms of AMD and from 0.6 to 2.6% for late AMD according to race, suggesting the existence of genetic differences among races. The purpose o
Externí odkaz:
https://doaj.org/article/d79d1f83d9364094a6dd654e6c0e8dd2
Autor:
Jae Won Yun, Lixing Yang, Hye-Young Park, Chang-Woo Lee, Hongui Cha, Hyun-Tae Shin, Ka-Won Noh, Yoon-La Choi, Woong-Yang Park, Peter J. Park
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background Gene fusions have been studied extensively, as frequent drivers of tumorigenesis as well as potential therapeutic targets. In many well-known cases, breakpoints occur at two intragenic positions, leading to in-frame gene-gene fusi
Externí odkaz:
https://doaj.org/article/7ade6c4de2c8414c8fc6c074745fd2d0
Autor:
Boram Lee, Ji Won Lee, Joon Ho Shim, Je-Gun Joung, Jae Won Yun, Joon Seol Bae, Hyun-Tae Shin, Ki Woong Sung, Woong-Yang Park
Publikováno v:
Translational Oncology, Vol 11, Iss 6, Pp 1390-1397 (2018)
PURPOSE: Relapsed/refractory pediatric cancers show poor prognosis; however, their genomic patterns remain unknown. To investigate the genetic mechanisms of tumor relapse and therapy resistance, we characterized genomic alterations in diagnostic and
Externí odkaz:
https://doaj.org/article/dfac7ad6766a4a19815a555a49e72777
Autor:
Hyun-Tae Shin, Yoon-La Choi, Jae Won Yun, Nayoung K. D. Kim, Sook-Young Kim, Hyo Jeong Jeon, Jae-Yong Nam, Chung Lee, Daeun Ryu, Sang Cheol Kim, Kyunghee Park, Eunjin Lee, Joon Seol Bae, Dae Soon Son, Je-Gun Joung, Jeeyun Lee, Seung Tae Kim, Myung-Ju Ahn, Se-Hoon Lee, Jin Seok Ahn, Woo Yong Lee, Bo Young Oh, Yeon Hee Park, Jeong Eon Lee, Kwang Hyuk Lee, Hee Cheol Kim, Kyoung-Mee Kim, Young-Hyuck Im, Keunchil Park, Peter J. Park, Woong-Yang Park
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
High-throughput sequencing is used to identify somatic variants in cancer patients. Here, the authors perform panel-based profiling of 5095 clinical samples and demonstrate that many clinically-actionable variants have low variant allele fractions, r
Externí odkaz:
https://doaj.org/article/e58ebe12efcc4384b527ed8e88824f94
Autor:
Gahee Park, Joo Kyung Park, Seung-Ho Shin, Hyo-Jeong Jeon, Nayoung K. D. Kim, Yeon Jeong Kim, Hyun-Tae Shin, Eunjin Lee, Kwang Hyuck Lee, Dae-Soon Son, Woong-Yang Park, Donghyun Park
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Targeted deep sequencing is increasingly used to detect low-allelic fraction variants; it is therefore essential that errors that constitute baseline noise and impose a practical limit on detection are characterized. In the presen
Externí odkaz:
https://doaj.org/article/3b112d69240a4eb8b342238163971c4b
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219682 (2019)
Intratumoral heterogeneity (ITH) refers to the presence of distinct tumor cell populations. It provides vital information for the clinical prognosis, drug responsiveness, and personalized treatment of cancer patients. As genomic ITH in various cancer
Externí odkaz:
https://doaj.org/article/cc5d24058bf74214a4b32719df9e9db0
Autor:
Jun Ho Ji, Young Lyun Oh, Mineui Hong, Jae Won Yun, Hyun-Woo Lee, DeokGeun Kim, Yongick Ji, Duk-Hwan Kim, Woong-Yang Park, Hyun-Tae Shin, Kyoung-Mee Kim, Myung-Ju Ahn, Keunchil Park, Jong-Mu Sun
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005467 (2015)
The genetic landscape of medullary thyroid cancer (MTC) is not yet fully understood, although some oncogenic mutations have been identified. To explore genetic profiles of MTCs, formalin-fixed, paraffin-embedded tumor tissues from MTC patients were a
Externí odkaz:
https://doaj.org/article/a805bbe59d5b42f7a919bcec94b47c4b
Autor:
Yoon-La Choi, Mi-Sook Lee, Se-Hoon Lee, Joungho Han, Sungbin An, Mingi Kim, Minjung Sung, Kyungsoo Jung, Yu-Jin Kim, Hyun-Tae Shin, Ji-Young Song, Insuk Sohn, Ka-Won Noh
Combination therapy of ALK and β3 inhibitors shows promising results in vivo and in ALK-rearranged NSCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588648e4d9c3cecaae9d68c239e7af84
https://doi.org/10.1158/1078-0432.22469529
https://doi.org/10.1158/1078-0432.22469529
