Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Hyun-Sook Hwang"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The influence of the sympathetic nervous system (SNS) on metabolism of bone and cartilage expressing β-adrenergic receptors (AR) was suggested. Here, we investigated whether the SNS functions as a modulator of cartilage metabolis
Externí odkaz:
https://doaj.org/article/68f08bb9d385418ca2347914056d14fc
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Tonicity-responsive enhancer-binding protein (TonEBP; nuclear factor of activated T cells 5) is a transcription factor that responds to changes in osmolality. However, recent studies have shown that it also modulates immune responses under i
Externí odkaz:
https://doaj.org/article/75633f9ad572436bb16d712adbe8d5b5
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Endothelial Per-Arnt-Sim domain protein-1/hypoxia-inducible factor-2α (EPAS-1/ HIF-2α) is a catabolic transcription factor that regulates osteoarthritis (OA)-related cartilage destruction. Here, we examined whether microRNA-365 (miR-365) a
Externí odkaz:
https://doaj.org/article/5766b98fe31c417b8d023770eb10cce2
Autor:
Namsuk Kim, Hyun-Sook Hwang
Publikováno v:
The Korean Society of Medicine & Therapy Science. 13:15-22
Publikováno v:
Osteoarthritis and Cartilage. 29:728-738
Summary Objective While the prevalence of radiographic and symptomatic osteoarthritis (OA) is higher in women, male mice are more frequently used in animal experiments to explore its pathogenesis or drug efficacy. In this study, we examined whether s
Autor:
Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Seon Ae Eom, Duk-Soo Kim, Eun Young Park, Jong Hoon Park, Sung-Woo Cho, Jinseu Park, Won Sik Eum, Ora Son, Hyun Sook Hwang, Soo Young Choi
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 561-566 (2013)
We examined the ways in which fenobam could promote not onlythe transduction of PEP-1-FK506BP into cells and tissues but alsothe neuroprotective effect of PEP-1-FK506BP against ischemicdamage. Fenobam strongly enhanced the protective effect ofPEP-1-F
Externí odkaz:
https://doaj.org/article/de978395df6948f3a475068a1cf19afa
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model
Autor:
Dae Won Kim, Sung Ho Lee, Sae Kwang Ku, Soo Hyun Cho, Sung-Woo Cho, Ga Hyeon Yoon, Hyun Sook Hwang, Jinseu Park, Won Sik Eum, Oh-Shin Kwon, Soo Young Choi
Publikováno v:
BMB Reports, Vol 46, Iss 2, Pp 124-129 (2013)
FK506 binding protein 12 (FK506BP) belongs to a family ofimmunophilins, and is involved in multiple biologicalprocesses. However, the function of FK506BP in cornealdisease remains unclear. In this study, we examined theprotective effects on dry eye d
Externí odkaz:
https://doaj.org/article/d6a7de7e84a94045a515e823c0955a23
Autor:
Dong Jin Go, Dong Hyun Kim, Ali Guermazi, Michel Daoud Crema, David J. Hunter, Hyun Sook Hwang, Hyun Ah Kim
Publikováno v:
International journal of rheumatic diseasesREFERENCES. 25(2)
Metabolic syndrome is a major health problem worldwide associated with obesity, thus drawing attention to its relation to osteoarthritis (OA). However, it is still uncertain whether metabolic syndrome or body fat distribution is associated with knee
Publikováno v:
BMB Reports
The nucleotide-binding and oligomerization domain (NOD) is an innate pattern recognition receptor that recognizes pathogen- and damage-associated molecular patterns. The 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) is a matrix degradation
Publikováno v:
BMB Reports
The cGAS-STING pathway plays an important role in pathogen-induced activation of the innate immune response. The 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) found predominantly in the synovial fluid of osteoarthritis (OA) patients increa