Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hyun-Seock Shin"'
Autor:
Sung Yong Lee, Jee Youn Oh, Tae Heung Kang, Hyun Seock Shin, Max A. Cheng, Emily Farmer, T.-C. Wu, Chien-Fu Hung
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-8 (2019)
Abstract Background Endoplasmic reticulum stress has a profound effect on cancer cell proliferation and survival, and also has the capacity to activate cells of the adaptive immune system. Multimodal treatment methods that utilize and combine convent
Externí odkaz:
https://doaj.org/article/9afff5b159544429802ca845115f0e17
Publikováno v:
Cancer Research & Treatment. Apr2022, Vol. 54 Issue 2, p458-468. 11p.
Publikováno v:
Cancer research and treatment. 54(2)
Purpose Histone deacetylase inhibitors (HDACis) are epigenetic regulators and used clinically for hematopoietic malignancies. Recently, HDACis have received attention as a factor that modulates the immune system. In this study, the role of histone de
Autor:
Hyun Seock Shin, Emily Farmer, Max A. Cheng, Tae Heung Kang, Jee Youn Oh, Chien Fu Hung, Sung Yong Lee, Tzyy Choou Wu
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-8 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
Background Endoplasmic reticulum stress has a profound effect on cancer cell proliferation and survival, and also has the capacity to activate cells of the adaptive immune system. Multimodal treatment methods that utilize and combine conventional can
Publikováno v:
Cancer Research. 80:4458-4458
Recently, Immune checkpoint inhibitor (ICI) has been widely applied to various types of cancer therapies and it is used as a treatment in clinical application. ICI has a higher effect on lung cancer than other cancers; however, the treatment efficien
Autor:
Jian Wu, Ritu Sarin, Neha Dixit, Edward P. Bowman, M. Eric Gershwin, Hyun-Seock Shin, Iannis E. Adamopoulos
Publikováno v:
The Journal of Immunology. 194:316-324
IL-23 has been well studied in the context of T cell differentiation; however, its role in the differentiation of myeloid progenitors is less clear. In this paper, we describe a novel role of IL-23 in myeloid cell differentiation. Specifically, we ha
Autor:
Iannis E. Adamopoulos, Hyun Seock Shin, Catherine Stanecki, Tiffany J. Dickerson, Erika Suzuki, Hong Qui
Publikováno v:
Journal of Autoimmunity. 39:369-376
Bone destruction is a common feature of inflammatory arthritis and is mediated by osteoclasts, the only specialized cells to carry out bone resorption. Aberrant expression of receptor activator of nuclear factor kappa β ligand (RANKL), an inducer of
Publikováno v:
Biochemical and Biophysical Research Communications. 385:273-278
The human ribosomal protein S3 (rpS3), a component of the 40S small subunit in the ribosome, is a known multi-functional protein with roles in DNA repair and apoptosis. We recently found that the arginine residue(s) of rpS3 are methylated by protein
Publikováno v:
Molecular and Cellular Biochemistry. 329:167-173
Nm23-H1 encodes nucleoside diphosphate kinase A (NDPK-A) and is known to have a metastasis suppressive activity in many tumor cells. However, it has many other functions as well. Recent studies have shown that the interacting proteins with Nm23-H1 wh
Publikováno v:
Journal of Biotechnology. 93:183-187
In order to develop a highly efficient mammalian expression vector, we constructed a vector by the combination of the murine cytomegalovirus (MCMV) immediate early (IE) promoter and the human elongation factor one alpha (EF-1 alpha) first intron. The