Zobrazeno 1 - 10
of 15 141
pro vyhledávání: '"Hyun-Ju An"'
Autor:
Seung-Chan An, Hak Hoon Jun, Kyeong Mi Kim, Issac Kim, Sujin Choi, Hyunjeong Yeo, Soonchul Lee, Hyun-Ju An
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1394 (2024)
Background/Objectives: Anaplastic thyroid cancer (ATC) is an aggressive and rare cancer with a poor prognosis, and traditional therapies have limited efficacy. This study investigates drug repositioning, focusing on auranofin, a gold-based drug origi
Externí odkaz:
https://doaj.org/article/a87c6935b3364a2a9e92ddf0103e3bf4
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/2f530937da024639bbbfac4cfc787be4
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6605 (2024)
We fabricated a microfluidic chip (osteoblast [OB]–osteoclast [OC] chip) that could regulate the mixture amounts of OB and OC supernatants to investigate the effect of different supernatant distributions on osteogenesis or osteoclastogenesis. Compu
Externí odkaz:
https://doaj.org/article/7bf1c3dc66b0417d8a978ea29aa1ae4b
Autor:
Hye Yun Jeong, Hyun-Ju An, Min Ji Sung, Min Heui Ha, Yu Ho Lee, Dong Ho Yang, Tae Young Yang, Dohyun Han, So-Young Lee
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract The prevalence of chronic kidney disease (CKD) is steadily increasing, and it is a global health burden. Exercise has been suggested to improve physical activity and the quality of life in patients with CKD, eventually reducing mortality. Th
Externí odkaz:
https://doaj.org/article/b1a1747173194ceca0812a00f0a513cb
Autor:
Dong Eun Shin, Younghun Lee, Hyun-Ju An, Tae-Sun Hwang, Jin-Woo Cho, Jongbeom Oh, Wooyeol Ahn, Jaemin Lee, Chul Gie Hong, Yeonju Lee, Soonchul Lee
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundOsteoporotic vertebral compression fractures commonly involve the superior vertebral body; however, their associated causes have not yet been clearly established. This study aimed to determine the trabecular structural differences between t
Externí odkaz:
https://doaj.org/article/8ea04bc7d4c84d25b9812f6d69f51457
Autor:
So-Young Lee, Hyun-Ju An, Jin Man Kim, Min-Ji Sung, Do Kyung Kim, Hyung Kyung Kim, Jongbeom Oh, Hye Yun Jeong, Yu Ho Lee, Taeyoung Yang, Jun Han Kim, Ha Jeong Lim, Soonchul Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background PTEN-induced kinase 1 (PINK1) is a serine/threonine-protein kinase in mitochondria that is critical for mitochondrial quality control. PINK1 triggers mitophagy, a selective autophagy of mitochondria, and is involved in mitochondri
Externí odkaz:
https://doaj.org/article/1be6bdaa122f4eaa98fa9e01194789de
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
MicroRNAs are key regulators of gene expression in tumorigenesis. In this study, we investigated the tumor-suppressive function of miR-31-3p. Analysis of the Gene Expression Omnibus database revealed that the expression of miR-31-3p in prostate cance
Externí odkaz:
https://doaj.org/article/c23f4d1134e349e09151b47cf6d57b44
Autor:
Kyeong Mi Kim, Hyun-Ju An, Sang-Hoon Kim, JuHee Kim, Changgon Sim, Jaemin Lee, Sin Hyung Park, Hyun Il Lee, Inseok Jang, Soonchul Lee
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveNumerous attempts have been made to devise treatments for ischemic foot ulcer (IFU), which is one of the most severe and fatal consequences of diabetes mellitus (DM). Pericytes, which are perivascular multipotent cells, are of interest as a
Externí odkaz:
https://doaj.org/article/577fb41899de4cd295f4889ebf8dfbf4
Publikováno v:
Diagnostics, Vol 12, Iss 10, p 2497 (2022)
A rotator cuff is a muscle and tendon surrounding the shoulder joint, and a rotator cuff tear can be caused by overuse or injury, which leads to great pain in affected individuals. However, rotator cuff tear is a multifactorial process whose underlyi
Externí odkaz:
https://doaj.org/article/58209254294249c982d0c86dc8244169
Autor:
Jin-Woo Kim, Hyun-Ju An, HyunJeong Yeo, Yunhui Jeong, HyeonHae Lee, Jusung Lee, Kisik Nam, Jongheon Lee, Dong-Eun Shin, Soonchul Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11355 (2021)
Intervertebral discs (IVDs) have poor nutrient diffusion, because the nucleus pulposus (NP) lacks direct vascular supply and likely generates adenosine triphosphate by anaerobic glycolysis. Regulation of glycolysis is mediated by hypoxia-inducible fa
Externí odkaz:
https://doaj.org/article/1a45b351db8c44de82ed8f5a756b4273