Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hyun-Hee Kwak"'
Autor:
Su Jin Kim, Sung Yoon Cho, Sung Won Park, Jinsup Kim, Dong-Kyu Jin, Ah-Ra Ko, Hyun-Hee Kwak, Rimm Huh, Young Bae Sohn
Publikováno v:
Molecular Pharmaceutics. 12:3759-3765
The current recombinant human growth hormone (rhGH) therapy requires daily subcutaneous (sc) injections, which results in poor patient compliance, especially in young children. To reduce the dosing frequency, we generated a chimeric protein of rhGH a
Autor:
Soo-Hyoung Kang, Chang-Koo Shim, Hyun-Jun Youn, Hyun-Hee Kwak, Mi-Kyung Son, Tae Hyoung Kim, Won-Sik Shim, Yoon Ji Kim
Publikováno v:
European Journal of Pharmaceutical Sciences. 40:103-109
Exenatide must be administered serially by twice-daily subcutaneous (SC) injection due to its short half-life. The purpose of the present study is to develop an improved sustained-release exenatide formulation with a therapeutic efficacy comparable t
Autor:
Soo-Hyoung Kang, Yoon Ji Kim, Won-Sik Shim, Hyun-Jun Youn, Tae Hyoung Kim, Ghun-Il Lee, Hyun-Hee Kwak, Chang-Koo Shim, Mi-Kyung Son, Zee-Hye Yoon, Seong-Mee Hwang
Publikováno v:
Pharmaceutical Research. 26:2504-2512
To develop an improved sustained-release (SR) formulation of exenatide (a therapy for patients with type 2 diabetes mellitus) in a biweekly dosage form with therapeutic efficacy comparable to that achieved with twice-daily injections of the drug.A SR
Autor:
Hyun Hee Kwak, Han K. Chung, Seul Min Choi, Joo H. Lee, Myung Gyoon Lee, Jong W. Kwon, Jong O. Kim, Moohi Yoo, Jung H. Kim
Publikováno v:
Biopharmaceutics & Drug Disposition. 27:141-145
It was reported that gastric motility was delayed and gastric acid secretion was reduced in vagotomized dogs which mimics a low gastric acidity in humans. A delay in gastric motility causes long residence of amlodipine in the stomach. More unionized
Publikováno v:
Arzneimittel-Forschung. 55(10)
The vascular changes associated with early diabetic retinopathy, which include the formation of microaneurysms and acellular capillaries, vessel dilation, vascular endothelial growth factor expression, were investigated experimentally in streptozotoc
Autor:
Byong-Moon Kim, Su-Hyung Park, Young Chul Sung, Jun Chang, Se-Hwan Yang, Hyeju Kim, Hyun-Hee Kwak, Sung Hee Lee
Publikováno v:
Immune Network. 7:186
Background: Although IL-12 has been widely accepted to play a central role in the control of pathogen infection, the use of recombinant IL-12 (rIL-12) as a vaccine adjuvant has been known to be ineffective because of its rapid clearance in the body.
Publikováno v:
Drug Research / Arzneimittel-Forschung (Editio Cantor Verlag fur Medizin und Naturwissenschaften); Oct2005, Vol. 55 Issue 10, p573-580, 8p