Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Hyun Soo Shim"'
Autor:
Taehun Lim, Shivani Rajoriya, Bohyeon Kim, Augustine Natasha, Hyeonjoo Im, Hyun Soo Shim, Junsang Yoo, Jong Woo Kim, Eun-Woo Lee, Hye Jin Shin, Soon Ha Kim, Won-Keun Kim
Publikováno v:
Virus Research, Vol 342, Iss , Pp 199325- (2024)
The COVID-19 pandemic caused by SARS-CoV-2 becomes a serious threat to global health and requires the development of effective antiviral therapies. Current therapies that target viral proteins have limited efficacy with side effects. In this study, w
Externí odkaz:
https://doaj.org/article/808e3e370a074b309e11d12619df0274
Autor:
Hyun-Jung Park, Hyun Soo Shim, Ah-Reum Han, Eun-Kyoung Seo, Kyu-Ri Kim, Bong Hee Han, Insop Shim
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 3, Pp 1407-1416 (2022)
(1) Background: Three isolated compounds from Physalis alkekengi var. franchetii (PAF) have been investigated to possess a variety of biological activities. Their structures were elucidated by spectroscopic analysis (Ultraviolet (UV), High-resolution
Externí odkaz:
https://doaj.org/article/3ccb28e7eb7b4380b726b35d373cd08a
Autor:
Yujung Chang, Sungwoo Lee, Jieun Kim, Chunggoo Kim, Hyun Soo Shim, Seung Eun Lee, Hyeok Ju Park, Jeongwon Kim, Soohyun Lee, Yong Kyu Lee, Sungho Park, Junsang Yoo
Publikováno v:
Nanomaterials, Vol 13, Iss 10, p 1680 (2023)
Gene therapy is an innovative approach in the field of regenerative medicine. This therapy entails the transfer of genetic material into a patient’s cells to treat diseases. In particular, gene therapy for neurological diseases has recently achieve
Externí odkaz:
https://doaj.org/article/65f150bd79ff4c7c9a5c473841551e8d
Publikováno v:
Animal Cells and Systems, Vol 0, Iss 0, Pp 1-9 (2020)
Acer tegmentosum (ATM) has antioxidant and anti-adipogenic activity. However, few studies have investigated the pharmacological activity or mechanism of ATM as an antidepressant agent. We assessed the antidepressant effect of ATM in modulating menopa
Externí odkaz:
https://doaj.org/article/53a75717e6df4818b26298b26d9f0062
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Menopause is a risk factor of anxiety and depression. Also, psychoneurological symptoms are shown in almost all women in the perimenopausal period. The present study investigated if repeated stress modulates behavioral changes or the balance of pro-
Externí odkaz:
https://doaj.org/article/a5e7965e79894573a92ba0663517bbaa
Autor:
Hyun-Jung Park, Hyun Soo Shim, Sunyoung Lee, Dae Hyun Hahm, Hyejung Lee, Chang Taek Oh, Hae Jung Han, Hyi Jeong Ji, Insop Shim
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory and anti-nociceptive ac
Externí odkaz:
https://doaj.org/article/67b93f78204e47eda10fde0a044de7d1
Publikováno v:
Animal Cells and Systems, Vol 22, Iss 1, Pp 37-44 (2018)
The supramammillary area (SUM) of the hypothalamus has wide spread connection with numerous brain structures. It is known that the SUM can control the frequency of the hippocampal theta rhythm, which plays a role in the cognitive functions of the hip
Externí odkaz:
https://doaj.org/article/7ec14c4eea4948b9968d7d4aafbc37c6
Publikováno v:
Journal of Clinical Pharmacology and Therapeutics. 3:29-33
What is known and objectives: Spinal Cord Injury (SCI) is defined for the last few decades as patients getting wheelchair bound and under medication for a lifetime [1]. Medical battery for SCI is very limited which often results in heightened frustra
Autor:
Sungwoo Lee, Hyun Soo Shim, Hyeok Ju Park, Yujung Chang, Young-eun Han, Soo-Jin Oh, Wonwoong Lee, Hyeonjoo Im, YunHee Seol, Hoon Ryu, Hoon Kang, Yong Kyu Lee, Sungho Park, Junsang Yoo
Publikováno v:
Acta Biomaterialia. 151:561-575
The efficient production of dopaminergic neurons via the direct conversion of other cell types is of interest as a potential therapeutic approach for Parkinson's disease. This study aimed to investigate the use of elongated porous gold nanorods (AuNp
Autor:
Yulong Li, C. Justin Lee, Heejung Chun, Jinhyeong Joo, Hyun Soo Shim, Jaekwang Lee, Junsung Woo, Jinpyo Hong, Hyunji Kang, Hoon Ryu, Ye Eun Chun, Mingu Gordon Park, Sunpil Kim, Mijeong Park, Soo Jin Oh, Jiesi Feng, Moonsun Sa, Wuhyun Koh, Seung Eun Lee, Jeiwon Cho
Publikováno v:
Biological Psychiatry. 91:740-752
Background NMDAR hypofunction has been implicated in several psychiatric disorders with an impairment of cognitive flexibility. However, the molecular mechanism of how NMDAR hypofunction with decreased NMDAR tone causes the impairment of cognitive fl