Výsledky vyhledávání - "Hyun Sil Park"

A distinct tolerogenic subset of splenic IDO+CD11b+ dendritic cells from orally tolerized mice is responsible for induction of systemic immune tolerance and suppression of collagen-induced arthritis

Autor: Ho-Youn Kim, Mi La Cho, Sue Yun Hwang, Mi Kyung Park, Kyung Su Park, So Youn Min, Min-Jung Park, Hyun Sil Park, Sung Hwan Park

Publikováno v: Cellular Immunology. 278:45-54

In oral tolerance, locally instigated tolerance in the gut propagate to systemic tolerance. In order to investigate the mechanism, we analyzed indoleamine 2,3-dioxygenase (IDO) expression in splenic dendritic cell (DC) subsets and tested whether DCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6125f2f97a837cc2f584e9ff6fc701b0
https://doi.org/10.1016/j.cellimm.2012.06.009

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Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway

Autor: Min-Jung Park, Jack Hutcheson, Tianfu Wu, So Youn Min, Ramesh Saxena, Jiankun Zhu, Kamala Vanarsa, Yuyang Fu, Yong Du, Hyun Sil Park, Ho-Youn Kim, Chandra Mohan, Elhaum Khobahy

Publikováno v: Clinical Immunology. 143:59-72

Catheters are implanted into the peritoneal cavity during the process of peritoneal dialysis. Though these catheters may be effective and beneficial, the impact of catheters on the immune system is poorly understood. Catheters and other devices impla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fc82ea2bcbf2b4dcf6cca5d64fff4a
https://doi.org/10.1016/j.clim.2012.01.003

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Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis

Autor: Hye Joa Oh, Mi La Cho, Byung Ha Chung, Min-Jung Park, Seok-Goo Cho, Jong Wook Lee, So Youn Min, Ho-Youn Kim, Young Gue Cho, Hyun Sil Park

Publikováno v: Arthritis & Rheumatism. 63:1668-1680

Objective Bone marrow–derived mesenchymal stem cells (MSCs) can prevent various autoimmune diseases. We examined the therapeutic potential of transforming growth factor β (TGFβ)–transduced MSCs in experimental autoimmune arthritis, using an acc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16938b90f95dfc56f9473cd096e757e0
https://doi.org/10.1002/art.30326

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Treatment with N-tosyl-l-phenylalanine chloromethyl ketone after the onset of collagen-induced arthritis reduces joint erosion and NF-κB activation

Autor: Hyun Sil Park, Kyung Ho Ha, So Youn Min, Min-Jung Park, Jin Choi, Ho-Youn Kim, Hye Joa Oh, Dae Myung Jue, Ji Hyeon Ju, Mi Sun Byun

Publikováno v: European Journal of Pharmacology. 595:108-113

N-tosyl-l-phenylalanine chloromethyl ketone (TPCK) is known to inhibit NF-kappaB activation and the expression of inflammation mediators in cultured cells. We measured the potential of TPCK to inhibit the pathogenesis of collagen-induced arthritis by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60aff63f0295c345d8f1c66cddeb86e
https://doi.org/10.1016/j.ejphar.2008.07.056

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The lupus susceptibility locus Sle1 facilitates the peripheral development and selection of anti-DNA B cells through impaired receptor editing (P4054)

Autor: Hang-Rae Kim, Soog-Hee Chang, Tae-Joo Kim, Young-Joo Kim, Yang Liu, So-Youn Min, Min-Jung Park, Hyun-Sil Park, Ki-Hoan Nam, Seung-Young Seong, Ho-Youn Kim, Chandra Mohan

Publikováno v: The Journal of Immunology. 190:44.12-44.12

Systemic lupus erythematosus is characterized by the spontaneous production of IgG autoantibodies in patients and lupus-prone mice. In this study, we investigated the effect of the Sle1 lupus susceptibility locus on the peripheral development of 56R+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c264f7357b8bc155e41e73ca75d7d075
https://doi.org/10.4049/jimmunol.190.supp.44.12

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IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice

Autor: Seok-Goo Cho, Hye Joa Oh, Ho-Youn Kim, Hyun Sil Park, Mi La Cho, Min-Jung Park, Bo Young Yoon, Jung Yeon Lim

Publikováno v: Experimental & Molecular Medicine

IL-17-producing CD4+ T cells (Th17) play important functions in autoimmune diseases and allograft rejection of solid organs. We examined the effects of IL 17 and its mechanism of action on arthritis in a murine collagen-induced arthritis (CIA) model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c8578a611be9200a39ef737ff30cf1
https://doi.org/10.3858/emm.2012.44.11.078

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Bone Marrow T Cells are Superior to Splenic T Cells to Induce Chimeric Conversion After Non-Myeloablative Bone Marrow Transplantation

Autor: Seok Lee, Chang-Ki Min, Hong Seok Chang, So Youn Min, Seok-Goo Cho, Hee-Je Kim, Hyun Sil Park, Woo Sung Min, Min-Jung Park, Chun Choo Kim, Jong Wook Lee, Ho-Youn Kim

Publikováno v: The Korean Journal of Internal Medicine

BACKGROUND/AIMS: The bone marrow functions not only as the primary B-lymphocyte-producing organ but also as a secondary lymphoid organ for CD4 and CD8 cell responses and a site of preferential homing and persistence for memory T cells. Bone marrow T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc59c4867877e078f970ad15c7ec2d5
https://doi.org/10.3904/kjim.2009.24.3.252

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