Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Hyun Shik Lee"'
Autor:
Seung Un Seo, Seon Min Woo, Seul Gi Lee, Min Yeong Kim, Hyun Shik Lee, Yung Hyun Choi, Sang Hyun Kim, Young-Chae Chang, Kyoung-jin Min, Taeg Kyu Kwon
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102336- (2022)
Cathepsin K inhibitor (odanacatib; ODN) and cathepsin K knockdown (siRNA) enhance oxaliplatin-induced apoptosis through p53-dependent Bax upregulation. However, its underlying mechanisms remain unclear. In this study, we elucidated the mechanism behi
Externí odkaz:
https://doaj.org/article/fc26d19e9df043848e42839342453da0
Autor:
Tayaba Ismail, Hyun-Kyung Lee, Hongchan Lee, Youni Kim, Eunjeong Kim, Jun-Yeong Lee, Kee-Beom Kim, Hong-Yeoul Ryu, Dong-Hyung Cho, Taeg Kyu Kwon, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115820- (2024)
Perfluorooctanesulfonate (PFOS) is a ubiquitous environmental pollutant associated with increasing health concerns and environmental hazards. Toxicological analyses of PFOS exposure are hampered by large interspecies variations and limited studies on
Externí odkaz:
https://doaj.org/article/d257ce8b07ab4f1697495e2f06ce8165
Autor:
Ji-Eun Bae, Soyoung Jang, Joon Bum Kim, Hyejin Hyung, Na Yeon Park, Yong Hwan Kim, So Hyun Kim, Seong Hyun Kim, Jin Min Ha, Gyeong Seok Oh, Kyuhee Park, Kwiwan Jeong, Jae Seon Jang, Doo Sin Jo, Pansoo Kim, Hyun-Shik Lee, Zae Young Ryoo, Dong-Hyung Cho
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract The primary cilium, an antenna-like structure on the cell surface, acts as a mechanical and chemical sensory organelle. Primary cilia play critical roles in sensing the extracellular environment to coordinate various developmental and homeos
Externí odkaz:
https://doaj.org/article/f175325e780a49ceb0b5e76fcd8f1af9
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1843-1850 (2023)
The budding yeast Saccharomyces cerevisiae is a well-characterized and popular model system for investigating histone modifications and the inheritance of chromatin states. The data obtained from this model organism have provided essential and critic
Externí odkaz:
https://doaj.org/article/7fccd10a75414d86904ecdb2bef6039e
Autor:
Seung Un Seo, Seon Min Woo, Seung-Soon Im, Younghoon Jang, Eugene Han, Sang Hyun Kim, Hongchan Lee, Hyun-Shik Lee, Ju-Ock Nam, Edward Gabrielson, Kyoung-jin Min, Taeg Kyu Kwon
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-13 (2022)
Abstract Cathepsin D (Cat D) is well known for its roles in metastasis, angiogenesis, proliferation, and carcinogenesis in cancer. Despite Cat D being a promising target in cancer cells, effects and underlying mechanism of its inhibition remain uncle
Externí odkaz:
https://doaj.org/article/7b38673b8e814d76a1ecfc3f03ada1f7
Publikováno v:
Experimental and Molecular Medicine, Vol 53, Iss 11, Pp 1683-1688 (2021)
Cell biology: Interaction of DNA-winding proteins ensures correct gene expression Crosstalk between different DNA-winding proteins, or histones, is a mechanism of molecular fidelity that helps prevent the initiation of aberrant gene expression, which
Externí odkaz:
https://doaj.org/article/b7cf57632e8a48a381b88dd44b26e808
Autor:
Dong Gil Jang, Keun Yeong Kwon, Yeong Cheon Kweon, Byung-gyu Kim, Kyungjae Myung, Hyun-Shik Lee, Chan Young Park, Taejoon Kwon, Tae Joo Park
Publikováno v:
eLife, Vol 11 (2022)
The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction protein α1 (GJA1) is the most commonly expressed subunit. A recent study showed that GJA1 is necessary for the maintenance of mo
Externí odkaz:
https://doaj.org/article/b10320ea19874a318706403064d7951a
Autor:
Ji-Eun Bae, Joon Bum Kim, Doo Sin Jo, Na Yeon Park, Yong Hwan Kim, Ha Jung Lee, Seong Hyun Kim, So Hyun Kim, Mikyung Son, Pansoo Kim, Hong-Yeoul Ryu, Won Ha Lee, Zae Young Ryoo, Hyun-Shik Lee, Yong-Keun Jung, Dong-Hyung Cho
Publikováno v:
Cells, Vol 11, Iss 17, p 2722 (2022)
Primary cilia help to maintain cellular homeostasis by sensing conditions in the extracellular environment, including growth factors, nutrients, and hormones that are involved in various signaling pathways. Recently, we have shown that enhanced prima
Externí odkaz:
https://doaj.org/article/3943055abb2e46c4b9f1fdc64b80c9a5
Autor:
Jiwon Ko, Soyoung Jang, Wookbong Kwon, Si-Yong Kim, Soyeon Jang, Eungyung Kim, Young-Rae Ji, Sijun Park, Myoung-Ok Kim, Seong-Kyoon Choi, Dong-Hyung Cho, Hyun-Shik Lee, Su-Geun Lim, Zae-Young Ryoo
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 189 (2022)
The effect of glucose-dependent insulinotropic polypeptide (GIP) on cells under oxidative stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms were assessed in the present study. We found that in the pre-treatment
Externí odkaz:
https://doaj.org/article/bddcef9aefec4d7c85ade52fe497cf66
Autor:
Hongchan Lee, Na Young Lee, Youni Kim, Hong-Seok Choi, Tayaba Ismail, Hong-Yeoul Ryu, Dong-Hyung Cho, Zae Young Ryoo, Dong-Seok Lee, Taeg Kyu Kwon, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1636 (2021)
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have been studied for their antioxidant functions and roles in cancers. However, the physiological significance of Gpx1 and Prdx2 d
Externí odkaz:
https://doaj.org/article/9eb7beabec5547b18ab2cb1ab021160d