Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hyun Se Kim Lee"'
Autor:
Mireille Khoury, Qianqian Guo, Kunimaro Furuta, Cristina Correia, Chady Meroueh, Hyun Se Kim Lee, Khaled Warasnhe, Lucía Valenzuela-Pérez, Andrew P. Mazar, Iljung Kim, Yung-Kyun Noh, Heather Holmes, Michael F. Romero, Caroline R. Sussman, Kevin D. Pavelko, Shahidul Islam, Adebowale O. Bamidele, Petra Hirsova, Hu Li, Samar H. Ibrahim
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101073- (2024)
Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by excessive circulating toxic lipids, hepatic steatosis, and liver inflammation. Monocyte adhesion to liver sinusoidal endothelial cells (LSECs) and transend
Externí odkaz:
https://doaj.org/article/140f68733e754e61917380b70dbef94e
Autor:
David J. Friedman, Monika Kizerwetter, Paul Belmonte, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Michael J. Shapiro, Haidong Dong, Virginia Smith Shapiro
Publikováno v:
The Journal of Immunology. 208:1845-1850
Inhibitory receptors have a critical role in the regulation of immunity. Siglecs are a family of primarily inhibitory receptors expressed by immune cells that recognize specific sialic acid modifications on cell surface glycans. Many tumors have incr
Autor:
Dohnalkova, Ester, Bayer, Rachel L., Qianqian Guo, Bamidele, Adebowale O., Hyun Se Kim Lee, Valenzuela-Pérez, Lucía, Krishnan, Anuradha, Pavelko, Kevin D., Guisot, Nicolas E. S., Bunyard, Peter, Young-Bum Kim, Ibrahim, Samar H., Gores, Gregory J., Hirsova, Petra
Publikováno v:
Hepatology Communications; Jun2023, Vol. 7 Issue 6, p1-15, 15p
Autor:
Brandon Lee Maniaci, David Friedman, Sydney Crotts, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Virginia Shapiro
Publikováno v:
The Journal of Immunology. 208:61.02-61.02
The lifetime risk for colorectal cancer in the United States is approximately 4%. Individuals with Inflammatory Bowel Disease, including Ulcerative Colitis and Crohn’s Disease, have a substantially increased risk of developing colorectal cancer. Th
Autor:
Sydney B Crotts, Regina Antonetti, Michael J Shapiro, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Virginia Shapiro
Publikováno v:
The Journal of Immunology. 208:103.09-103.09
Inflammatory bowel disorders (IBD) including ulcerative colitis (UC) and Crohn’s disease (CD) affect between 1–3 million people in the United States with prevalence on the rise. Patients present with symptoms including diarrhea, abdominal cramps,
Autor:
Michael Jonathan Lehrke, Michael J Shapiro, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Virginia Smith Shapiro
Publikováno v:
The Journal of Immunology. 208:107.15-107.15
Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for matu
Autor:
Justin Choe, Paul Belmonte, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Michael J Shapiro, Virginia Shapiro
Publikováno v:
The Journal of Immunology. 208:174.09-174.09
In this study, we harnessed immunomodulatory Siglec-sialic acid interactions to mitigate autoimmune rejection of beta cells in Type 1 Diabetes (T1D). Mice engineered to express the sialyltransferase ST8Sia6 in beta cells (βST mice) were backcrossed