Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hyun O. Lee"'
Autor:
Barbara Szewczyk, René Günther, Julia Japtok, Moritz J. Frech, Marcel Naumann, Hyun O. Lee, Andreas Hermann
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112025- (2023)
Summary: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder causing progressive loss of motor neurons. Mutations in Fused in sarcoma (FUS) leading to its cytoplasmic mislocalization cause a subset of ALS. Under stress, mutant FUS loc
Externí odkaz:
https://doaj.org/article/adcf60dbf6714063851df8f52c3862a8
Autor:
Roxanne Oshidari, Richard Huang, Maryam Medghalchi, Elizabeth Y. W. Tse, Nasser Ashgriz, Hyun O. Lee, Haley Wyatt, Karim Mekhail
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Genome dynamics allow cells to repair DNA double-strand breaks (DSBs), which are highly toxic DNA lesions. Here the authors reveal that in S. cerevisiae, Rad52 DNA repair proteins assemble in liquid droplets that work with dynamic nuclear microtubule
Externí odkaz:
https://doaj.org/article/0334275f4fdc42f1b69c48d12f427599
Autor:
Lara Marrone, Ina Poser, Ian Casci, Julia Japtok, Peter Reinhardt, Antje Janosch, Cordula Andree, Hyun O. Lee, Claudia Moebius, Ellen Koerner, Lydia Reinhardt, Maria Elena Cicardi, Karl Hackmann, Barbara Klink, Angelo Poletti, Simon Alberti, Marc Bickle, Andreas Hermann, Udai Bhan Pandey, Anthony A. Hyman, Jared L. Sterneckert
Publikováno v:
Stem Cell Reports, Vol 10, Iss 2, Pp 375-389 (2018)
Summary: Perturbations in stress granule (SG) dynamics may be at the core of amyotrophic lateral sclerosis (ALS). Since SGs are membraneless compartments, modeling their dynamics in human motor neurons has been challenging, thus hindering the identif
Externí odkaz:
https://doaj.org/article/8c3c165643d94092bf3823929978ee6c
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Ipomoea L. is the largest genus within the Convolvulaceae and contains 600–700 species. Ipomoea species (morning glories) are economically valuable as horticultural species and scientifically valuable as ecological model plants to investigate matin
Externí odkaz:
https://doaj.org/article/f57fd196798b43b685384658edc2ec4e
Publikováno v:
RNA
Exciting recent work has highlighted that numerous cellular compartments lack encapsulating lipid bilayers (often called “membraneless organelles”), and that their structure and function are central to the regulation of key biological processes,
Autor:
Jeffrey A. Toretsky, Hyun O Lee, Michael L Nosella, Iva Pritišanac, Julie D. Forman-Kay, P. Andrew Chong, Maria Tereshchenko
Publikováno v:
Journal of the American Chemical Society. 143:11520-11534
Many membraneless organelles are thought to be biomolecular condensates formed by phase separation of proteins and other biopolymers. Post-translational modifications (PTMs) can impact protein phase separation behavior, although for many PTMs this as
Autor:
Dmitri Segal, Stefan Maier, Giovanni J. Mastromarco, Wesley Wei Qian, Syed Nabeel-Shah, Hyunmin Lee, Gaelen Moore, Jessica Lacoste, Brett Larsen, Zhen-Yuan Lin, Abeeshan Selvabaskaran, Karen Liu, Craig Smibert, Zhaolei Zhang, Jack Greenblatt, Jian Peng, Hyun O. Lee, Anne-Claude Gingras, Mikko Taipale
Publikováno v:
Molecular Cell. 83:974-993.e15
Publikováno v:
Encyclopedia of Biological Chemistry III ISBN: 9780128220405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f6cbb96d5093b36adb5659bbccd57c
https://doi.org/10.1016/b978-0-12-819460-7.00329-7
https://doi.org/10.1016/b978-0-12-819460-7.00329-7
Autor:
Ian Casci, Angelo Poletti, Julia Japtok, Claudia Moebius, Karl Hackmann, Marc Bickle, Udai Bhan Pandey, Barbara Klink, Ellen Koerner, Lydia Reinhardt, Antje Janosch, Anthony A. Hyman, Andreas Hermann, Simon Alberti, Lara Marrone, Cordula Andree, Jared Sterneckert, Peter Reinhardt, Ina Poser, Hyun O. Lee, Maria Elena Cicardi
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 2, Pp 375-389 (2018)
Stem cell reports 10(2), 375-389 (2018). doi:10.1016/j.stemcr.2017.12.018
Stem Cell Reports, Vol 10, Iss 2, Pp 375-389 (2018)
Stem cell reports 10(2), 375-389 (2018). doi:10.1016/j.stemcr.2017.12.018
Summary Perturbations in stress granule (SG) dynamics may be at the core of amyotrophic lateral sclerosis (ALS). Since SGs are membraneless compartments, modeling their dynamics in human motor neurons has been challenging, thus hindering the identifi