Výsledky vyhledávání

Evaluation of a novel approach to circulating tumor cell isolation for cancer gene panel analysis in patients with breast cancer

Autor: Myoung Shin Kim, Sung Ho Choi, Kap‑Seok Yang, Nak‑Jung Kwon, Jong Won Lee, Soojeong Lee, Pyeong‑Soo Park, Cham Han Lee, Dong Hyoung Lee, Du Yeol Han, Byung Ho Son, Woo Chung Lee, Hyun K. Lee, Jinseon Lee, Sei Hyun Ahn, Jong Han Yu, Byung Hee Jeon, Mi So Choi

Publikováno v: Oncology Letters

Liquid biopsy isolation of circulating tumor cells (CTCs) allows the genomic analysis of CTCs, which is useful in the determination of personalized cancer therapy. In the present study, CTCs from patients with breast cancer were enriched and successf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7151a7874488891badc4128f9c204992
https://doi.org/10.3892/ol.2017.5807

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Abstract 1586: Evaluation of AXL expression on circulating tumor cells from EGFR mutated lung cancer patients who have relapsed after the EGFR TKI treatment

Autor: Jun Sup Lee, Young Woong Sohn, Myoung Shin Kim, Hyun K. Lee, Young Hun Kim, Koichi Tazaki, Byung Hee Jeon, Kenji Nakamaru, Kenichi Wakita, Seokhyung Kim, Se-Hoon Lee, Jae Hyuk Lee

Publikováno v: Cancer Research. 78:1586-1586

Background: The EGFR (epidermal growth factor receptor) TKI (tyrosine kinase inhibitor) has become the standard treatment in lung cancer patients with EGFR mutations. When these patients are treated with EGFR TKI, 80~90% of the patients show response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19fdd2605f3672241c1bdbed1e842b62
https://doi.org/10.1158/1538-7445.am2018-1586

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Cancer panel analysis of circulating tumor cells in patients with breast cancer

Autor: Du Yeol Han, Pyeong‑Soo Park, Nak‑Jung Kwon, Jinseon Lee, Jong Won Lee, Dong Hyoung Lee, Kap‑Seok Yang, Woo Chung Lee, Jong Han Yu, Soojeong Lee, Hyun K. Lee, Byung Ho Son, Mi So Choi, Sung Ho Choi, Sei Hyun Ahn, Cham Han Lee, Byung Hee Jeon, Myoung Shin Kim

Publikováno v: Oncology letters. 16(1)

Liquid biopsy using circulating tumor cells (CTCs) is a noninvasive and repeatable procedure, and is therefore useful for molecular assays. However, the rarity of CTCs remains a challenge. To overcome this issue, our group developed a novel technolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e67f50080fc1d7a49e824cacbeb28e
https://pubmed.ncbi.nlm.nih.gov/29928447

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Mapping of the chromosome 19 q‐arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers

Autor: Cheryl L. Soderberg, David N. Louis, Bernd W. Scheithauer, Justin S. Smith, Thomas J. Borell, Arie Perry, Robert B. Jenkins, Andreas von Deimling, Ute Pohl, Sandra M. Hosek, Harvey W. Mohrenweiser, Issei Tachibana, Hyun K. Lee, Junqi Qian

Publikováno v: Genes, Chromosomes and Cancer. 29:16-25

Allelic loss of chromosome arm 19q is a frequent event in human diffuse glioma, suggesting the presence of a tumor suppressor gene. Previous loss of heterozygosity (LOH) analyses have mapped this gene to a 1.4-megabase interval, between the genetic m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2db43ddae0395774cfcf976577c92764
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1007>3.3.co

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A Transcript Map of the Chromosome 19q-Arm Glioma Tumor Suppressor Region

Autor: Justin S. Smith, Ute Pohl, Issei Tachibana, Hyun K. Lee, Bryce P. Portier, Robert B. Jenkins, Shivapriya Ramaswamy, Harvey W. Mohrenweiser, David N. Louis, Keisuke Ueki, Uma Thanarajasingam, Stephanie J. Billings

Publikováno v: Genomics. 64:44-50

Allelic loss of the chromosome 19q arm is a frequent event in human diffuse gliomas, suggesting that it contains a tumor suppressor gene. Recent deletion mapping studies have broadly implicated a 1.6-Mb interval between D19S241E and D19S596, with a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e482c808838eb407957c4c591de9c15
https://doi.org/10.1006/geno.1999.6101

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Non-invasive and repeatable EGFR analysis using novel enrichment method for circulating tumor cells

Autor: Pyeong-Soo Park, Mi So Choi, Ga-Yun Kim, Cham Han Lee, Sung Man Yoon, Byung Hee Jeon, Hyun K. Lee, Soo Jeong Lee, D. H. Lee, Jinseon Lee, Sung Ho Choi, Du Yeol Han

Publikováno v: Journal of Clinical Oncology. 33:e22033-e22033

e22033 Non-invasive and repeatable EGFR analysis using novel enrichment method for circulating tumor cells Background: The first-line treatment in confirmed NSCLC (non-small cell lung cancer) patie...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb4aba03a9a28217d285908ee569b8b0
https://doi.org/10.1200/jco.2015.33.15_suppl.e22033

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EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins

Autor: Harvey W. Mohrenweiser, Justin S. Smith, Issei Tachibana, Hyun K. Lee, Ute Pohl, Qiang Wu, Shivapriya Ramaswamy, David N. Louis, Robert B. Jenkins, Keisuke Ueki

Publikováno v: Genomics. 63(2)

Exon trapping from a bacterial artificial chromosome (BAC 78138) mapping to the 19q13.3 glioma tumor suppressor candidate region yielded two exons that recognized a 3.6-kb transcript on Northern blot. Screening of a human fetal brain cDNA library wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819d50d4303cb8b8d7ce9abdc4770627
https://pubmed.ncbi.nlm.nih.gov/10673336

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Cloning of a human ortholog (RPH3AL) of (RNO)Rph3al from a candidate 17p13.3 medulloblastoma tumor suppressor locus

Autor: Sharon Chiappa, Hyun K. Lee, Issei Tachibana, Robert B. Jenkins, Bryan McIver, Cory Allen, Corey Raffel, Justin S. Smith

Publikováno v: Genomics. 59(1)

Allelic loss of 17p13.3 is observed in approximately 40% of medulloblastomas, suggesting the presence of a tumor suppressor gene in this region. Deletion mapping has defined a region of common loss flanking the telomeric marker D17S34, and a recent r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5fbf20f6623b3bf53d0241362d534f
https://pubmed.ncbi.nlm.nih.gov/10395805

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Alterations of Chromosome Arms 1p and 19q as Predictors of Survival in Oligodendrogliomas, Astrocytomas, and Mixed Oligoastrocytomas

Autor: Hyun K. Lee, Peter C. Burger, Robert B. Jenkins, Sandra M. Hosek, Allan J. Yates, Judith R. O'Fallon, Arie Perry, David W. Kimmel, Justin S. Smith, Thomas J. Borell, Bernd W. Scheithauer

Publikováno v: Journal of Clinical Oncology. 18:636-636

PURPOSE: A recent report suggests that alterations of chromosome arms 1p and 19q are associated with chemotherapeutic response and overall survival in anaplastic oligodendroglioma patients treated with procarbazine, lomustine, and vincristine chemoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4585b180adb82e1f84a009d3530e1693
https://doi.org/10.1200/jco.2000.18.3.636

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