Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Hyun Ji, Noh"'
Autor:
Hyun Ji Noh, Jason Turner-Maier, S. Anne Schulberg, Michael L. Fitzgerald, Jeremy Johnson, Kaitlin N. Allen, Luis A. Hückstädt, Annabelle J. Batten, Jessica Alfoldi, Daniel P. Costa, Elinor K. Karlsson, Warren M. Zapol, Emmanuel S. Buys, Kerstin Lindblad-Toh, Allyson G. Hindle
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The Antarctic Weddell inhabits one of the most extreme environments on Earth. Comparative genomics with close relatives reveals the specific genetic adaptations for cardiovascular and fat metabolism that enable it to thrive.
Externí odkaz:
https://doaj.org/article/8e512fac09d54dce8a64472c5044d4ff
Autor:
Hyun Ji Noh, Ruqi Tang, Jason Flannick, Colm O’Dushlaine, Ross Swofford, Daniel Howrigan, Diane P. Genereux, Jeremy Johnson, Gerard van Grootheest, Edna Grünblatt, Erik Andersson, Diana R. Djurfeldt, Paresh D. Patel, Michele Koltookian, Christina M. Hultman, Michele T. Pato, Carlos N. Pato, Steven A. Rasmussen, Michael A. Jenike, Gregory L. Hanna, S. Evelyn Stewart, James A. Knowles, Stephan Ruhrmann, Hans-Jörgen Grabe, Michael Wagner, Christian Rück, Carol A. Mathews, Susanne Walitza, Daniëlle C. Cath, Guoping Feng, Elinor K. Karlsson, Kerstin Lindblad-Toh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder with symptoms including intrusive thoughts and time-consuming repetitive behaviors. Here Noh and colleagues identify genes enriched for functional variants associated with increased r
Externí odkaz:
https://doaj.org/article/0e2259c2b1d0444fa38da6636f417330
Autor:
Seo-Young Koo, Eun-Ji Park, Hyun-Ji Noh, Su-Mi Jo, Bo-Kyoung Ko, Hyun-Jin Shin, Chang-Woo Lee
Publikováno v:
International Journal of Molecular Sciences. 24:8441
Changes in the DNA damage response (DDR) and cellular metabolism are two important factors that allow cancer cells to proliferate. DDR is a set of events in which DNA damage is recognized, DNA repair factors are recruited to the site of damage, the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895e73ca0110500fb8f9ca42f6ae1093
https://doi.org/10.3390/ijms24098441
https://doi.org/10.3390/ijms24098441
Autor:
Kathleen Morrill, Jessica Hekman, Xue Li, Jesse McClure, Brittney Logan, Linda Goodman, Mingshi Gao, Yinan Dong, Marjie Alonso, Elena Carmichael, Noah Snyder-Mackler, Jacob Alonso, Hyun Ji Noh, Jeremy Johnson, Michele Koltookian, Charlie Lieu, Kate Megquier, Ross Swofford, Jason Turner-Maier, Michelle E. White, Zhiping Weng, Andrés Colubri, Diane P. Genereux, Kathryn A. Lord, Elinor K. Karlsson
Publikováno v:
Science
INTRODUCTION: Before the 1800s, dogs were probably primarily selected for functional roles such as hunting, guarding, and herding. Modern dog breeds are a recent invention defined by conformation to a physical ideal and purity of lineage. Breeds are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e2b16ad748f33d239c4c2c301437ce
https://pubmed.ncbi.nlm.nih.gov/35482869
https://pubmed.ncbi.nlm.nih.gov/35482869
Autor:
Drögemüller, Anna Letko, Katie M. Minor, Elaine M. Norton, Voichita D. Marinescu, Michaela Drögemüller, Emma Ivansson, Kate Megquier, Hyun Ji Noh, Mike Starkey, Steven G. Friedenberg, Kerstin Lindblad-Toh, James R. Mickelson, Cord
Publikováno v:
Genes; Volume 12; Issue 12; Pages: 1964
Dogs represent a unique spontaneous cancer model. Osteosarcoma (OSA) is the most common primary bone tumor in dogs (OMIA 001441-9615), and strongly resembles human forms of OSA. Several large- to giant-sized dog breeds, including the Leonberger, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::36c6b09224969a98ca430d2032b19453
Autor:
Noriko Tonomura, Ingegerd Elvers, Rachael Thomas, Kate Megquier, Jason Turner-Maier, Cedric Howald, Aaron L Sarver, Ross Swofford, Aric M Frantz, Daisuke Ito, Evan Mauceli, Maja Arendt, Hyun Ji Noh, Michele Koltookian, Tara Biagi, Sarah Fryc, Christina Williams, Anne C Avery, Jong-Hyuk Kim, Lisa Barber, Kristine Burgess, Eric S Lander, Elinor K Karlsson, Chieko Azuma, Jaime F Modiano, Matthew Breen, Kerstin Lindblad-Toh
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004922 (2015)
Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically simila
Externí odkaz:
https://doaj.org/article/5b00e49abada4f5abe8f6eab4d5205b1
Autor:
Hyun Ji Noh, Chris P Ponting, Hannah C Boulding, Stephen Meader, Catalina Betancur, Joseph D Buxbaum, Dalila Pinto, Christian R Marshall, Anath C Lionel, Stephen W Scherer, Caleb Webber
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003523 (2013)
Autism Spectrum Disorders (ASD) are highly heritable and characterised by impairments in social interaction and communication, and restricted and repetitive behaviours. Considering four sets of de novo copy number variants (CNVs) identified in 181 in
Externí odkaz:
https://doaj.org/article/fb31c2e77b0f4cce9f9517e06dcbc7bf
Autor:
Joseph D, Szustakowski, Suganthi, Balasubramanian, Erika, Kvikstad, Shareef, Khalid, Paola G, Bronson, Ariella, Sasson, Emily, Wong, Daren, Liu, J, Wade Davis, Carolina, Haefliger, A, Katrina Loomis, Rajesh, Mikkilineni, Hyun Ji, Noh, Samir, Wadhawan, Xiaodong, Bai, Alicia, Hawes, Olga, Krasheninina, Ricardo, Ulloa, Alex E, Lopez, Erin N, Smith, Jeffrey F, Waring, Christopher D, Whelan, Ellen A, Tsai, John D, Overton, William J, Salerno, Howard, Jacob, Sandor, Szalma, Heiko, Runz, Gregory, Hinkle, Paul, Nioi, Slavé, Petrovski, Melissa R, Miller, Aris, Baras, Lyndon J, Mitnaul, Jeffrey G, Reid, Zhan, Ye
Publikováno v:
Nature genetics. 53(7)
The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that will complete the sequencing of exomes for all ~500,000 UKB participants. Here, we describe t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c26601afe79e40887910a1cec958420
https://pubmed.ncbi.nlm.nih.gov/34267364
https://pubmed.ncbi.nlm.nih.gov/34267364
Autor:
Xiaodong Bai, Samir Wadhawan, Howard J. Jacob, Carolina Haefliger, Ariella Sasson, Rajesh Mikkilineni, Daren Liu, William J. Salerno, Jeffrey F. Waring, Joseph D. Szustakowski, Emily Wong, Paola G. Bronson, Ellen A. Tsai, Gregory Hinkle, Suganthi Balasubramanian, Alex Lopez, Olga Krasheninina, A. Katrina Loomis, E. N. Smith, Melissa R. Miller, Sándor Szalma, Hyun Ji Noh, Heiko Runz, Paul Nioi, Shareef Khalid, Christopher D. Whelan, Jeffrey G. Reid, Slavé Petrovski, Alicia Hawes, Lyndon J. Mitnaul, Ricardo Ulloa, John D. Overton, J. Wade Davis, Aris Baras, Erika Kvikstad
The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a unique private/public partnership between the UK Biobank and eight biopharma companies that will sequence the exomes of all ∼500,000 UK Biobank participants. Here we describe early results f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb73bd6db0a77f849067705497463ca
https://doi.org/10.1101/2020.11.02.20222232
https://doi.org/10.1101/2020.11.02.20222232
Autor:
Hyun Ji, Noh, Jason, Turner-Maier, S Anne, Schulberg, Michael L, Fitzgerald, Jeremy, Johnson, Kaitlin N, Allen, Luis A, Hückstädt, Annabelle J, Batten, Jessica, Alfoldi, Daniel P, Costa, Elinor K, Karlsson, Warren M, Zapol, Emmanuel S, Buys, Kerstin, Lindblad-Toh, Allyson G, Hindle
Publikováno v:
Communications biology. 5(1)
The Weddell seal (Leptonychotes weddellii) thrives in its extreme Antarctic environment. We generated the Weddell seal genome assembly and a high-quality annotation to investigate genome-wide evolutionary pressures that underlie its phenotype and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f69a29d302a7c2905e8fff22b266a34
https://pubmed.ncbi.nlm.nih.gov/35177770
https://pubmed.ncbi.nlm.nih.gov/35177770