Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Hyun Hee Leem"'
1
Akademický článek
Sec-O-glucosylhamaudol promotes the osteogenesis of pre-osteoblasts via BMP2 and Wnt3a signaling
Autor: Kyung-Ran Park, Hyun Hee Leem, Yoon-Ju Kwon, Il Keun Kwon, Jin Tae Hong, Hyung-Mun Yun
Publikováno v: Journal of Functional Foods, Vol 94, Iss , Pp 105112- (2022)
The perennial herb Saposhnikovia divaricata SCHISCHKIN, used as a source of traditional medicines, is known for its anti-bone erosion, anti-inflammatory, and analgesic effects. We examined the osteogenic properties of Sec-O-glucosylhamaudol (SOGH) ex
Externí odkaz: https://doaj.org/article/0b821d938a85454f95551359fb329241
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2
Akademický článek
The Guanidine Pseudoalkaloids 10-Methoxy-Leonurine and Leonurine Act as Competitive Inhibitors of Tyrosinase
Autor: Jang Hoon Kim, Hyun Hee Leem, Ga Young Lee
Publikováno v: Biomolecules, Vol 10, Iss 2, p 174 (2020)
Tyrosinase plays a key role in the production of melanin. A variety of industrial fields have shown interest in the development of tyrosinase inhibitors from plants. In this study, compounds 1−5 derived from Leonurus japonicas were evaluated to det
Externí odkaz: https://doaj.org/article/c85c58df1630463ebe6e95cbf75907ff
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5
Falcarindiol Stimulates Apoptotic and Autophagic Cell Death to Attenuate Cell Proliferation, Cell Division, and Metastasis through the PI3K/AKT/mTOR/p70S6K Pathway in Human Oral Squamous Cell Carcinomas
Autor: Kyung-Ran Park, Hyun Hee Leem, Yoon-Ju Kwon, Il Keun Kwon, Jin Tae Hong, Hyung-Mun Yun
Publikováno v: The American journal of Chinese medicine. 50(1)
Human oral squamous cell carcinomas (OSCCs) have high cancer mortality and a 5-year survival rate lower than that of most other carcinomas. New therapeutic strategies are required for the treatment and prevention against OSCCs. An approach to cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43508d015a17517e487c11f23051ecf4
https://pubmed.ncbi.nlm.nih.gov/34931585
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6
Potent inhibition of acetylcholinesterase by sargachromanol I from Sargassum siliquastrum and by selected natural compounds
Autor: MyoungLae Cho, Jong Min Oh, Hyun Hee Leem, Hoon Kim, Daeui Park, Seung Cheol Baek, Jae Pil Lee, Myung-Gyun Kang, Joon Yeop Lee
Publikováno v: Bioorganic chemistry. 89
Six hundred forty natural compounds were tested for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. Of those, sargachromanol I (SCI) and G (SCG) isolated from the brown alga Sargassum siliquastrum, dihydroberberine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ad3f69b4a9d027075ae6c8669f2dbe
https://pubmed.ncbi.nlm.nih.gov/31200287
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7
Chrysophanol Suppressed Glutamate-Induced Hippocampal Neuronal Cell Death via Regulation of Dynamin-Related Protein 1-Dependent Mitochondrial Fission
Autor: Hyun-Shik Lee, Hong Jun Lee, Ju-Sik Min, Unbin Chae, Sang-Rae Lee, Hyun Hee Leem, Dong-Seok Lee
Publikováno v: Pharmacology. 100:153-160
Chrysophanic acid, or chrysophanol, is an anthraquinone found in Rheum palmatum, which was used in the preparation of oriental medicine in ancient China. The hippocampus plays a major role in controlling the activities of the short- and long-term mem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280e2cc430376abec8bb8e45a82b7282
https://doi.org/10.1159/000477814
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8
Effects of the amide alkaloid piperyline on apoptosis, autophagy, and differentiation of pre-osteoblasts
Autor: Hyung Mun Yun, Hyun Hee Leem, Kyung Ran Park, Myoung Lae Cho, Sang Wook Kang
Publikováno v: Phytomedicine. 79:153347
Background Amide alkaloidsare typical constituents in plants of the Piperaceae family. Most of the pharmacological properties of Piper nigrum L. are attributed to the major amide alkaloid, piperine. Piperyline (PIPE) is a further amide alkaloid that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34516dd037cee6e8306e090e11230612
https://doi.org/10.1016/j.phymed.2020.153347
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9
The Antitumor Natural Compound Falcarindiol Disrupts Neural Stem Cell Homeostasis by Suppressing Notch Pathway
Autor: Mingyu Kang, Tae-Jun Kim, Hyun-Sook Kwon, Kyung-Ha Lee, Do-Yeon Kim, Hyun Hee Leem
Publikováno v: International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3432 (2018)
Neural stem cells (NSCs) are undifferentiated, multi-potent cells that can give rise to functional neurons and glial cells. The disruption in NSC homeostasis and/or the impaired neurogenesis lead to diverse neurological diseases, including depression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff9d054509ba70ec978893973554cb3
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10
The Guanidine Pseudoalkaloids 10-Methoxy-Leonurine and Leonurine Act as Competitive Inhibitors of Tyrosinase
Autor: Hyun Hee Leem, Ga Young Lee, Jang Hoon Kim
Publikováno v: Biomolecules
Volume 10
Issue 2
Biomolecules, Vol 10, Iss 2, p 174 (2020)
Tyrosinase plays a key role in the production of melanin. A variety of industrial fields have shown interest in the development of tyrosinase inhibitors from plants. In this study, compounds 1&ndash
5 derived from Leonurus japonicas were evaluat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31adae690480b96465cc8957baf48aa1
https://doi.org/10.3390/biom10020174
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