Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hyun B. Chun"'
Autor:
Kaoru Saijo, Iryna Prots, Jürgen Winkler, Christopher K. Glass, Jenhan Tao, Hyun B. Chun, David Gosselin, Johannes C. M. Schlachetzki, Beate Winner
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Microglia are the main immune cells of the brain and express a large genetic pattern of genes linked to Parkinson's disease risk alleles. Monocytes like microglia are myeloid-lineage cells, raising the questions of the extent to which they share gene
Autor:
Hyun B. Chun, Timothy V. Pham, Dylan Skola, Alok R. Singh, Donald L. Durden, Guillermo A. Morales, Muamera Zulcic, Christopher K. Glass, Kevin X. Liu, Joseph R. Garlich, Shweta Joshi
Publikováno v:
Molecular cancer therapeutics, vol 18, iss 6
Mol Cancer Ther
Mol Cancer Ther
Macrophages (MΘs) are key immune infiltrates in solid tumors and serve as major drivers behind tumor growth, immune suppression, and inhibition of adaptive immune responses in the tumor microenvironment (TME). Bromodomain and extraterminal (BET) pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a343d9a4c13a59d08289183cb7fcdd
https://escholarship.org/uc/item/7sj6f8cd
https://escholarship.org/uc/item/7sj6f8cd
Autor:
Iryna Prots, Christopher K. Glass, Hyun B. Chun, Johannes C. M. Schlachetzki, Beate Winner, Jürgen Winkler, Kaoru Saijo, Jenhan Tao, David Gosselin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Microglia are the main immune cells of the brain and express a large genetic pattern of genes linked to Parkinson’s disease risk alleles. Monocytes like microglia are myeloid-lineage cells, raising the questions of the extent to which they share ge
Autor:
Rongxin Fang, Dylan Skola, Emma M. Westin, Gregory J. Fonseca, Bing Ren, Christopher K. Glass, Dirk Metzler, Casey E. Romanoski, Miao Yu, Verena M. Link, Tobias Strid, Ty D. Troutman, Inge R. Holtman, Mashito Sakai, Yohei Abe, Sascha H. Duttke, Marten A. Hoeksema, Nathanael J. Spann, Rong Hu, Jenhan Tao, Hyun B. Chun
Publikováno v:
Cell, vol 173, iss 7
Cell, 173(7), 1796-1809.e17. Cell Press
Cell, 173(7), 1796-1809.e17. CELL PRESS
Cell, 173(7), 1796-1809.e17. Cell Press
Cell, 173(7), 1796-1809.e17. CELL PRESS
Non-coding genetic variation is a major driver of phenotypic diversity and allows the investigation of mechanisms that control gene expression. Here, we systematically investigated the effects of >50 million variations from five strains of mice on mR
Publikováno v:
Cancer Research. 70:10131-10140
Gliomas generally infiltrate the surrounding normal brain parenchyma, a process associated with increased vascular permeability (VP) and dysregulation of the blood–brain barrier (BBB). However, the molecular mechanisms underlying glioma-induced VP
Autor:
Xitong Dang, Hyun B. Chun, Raul Coimbra, David M. Cauvi, Brian P. Eliceiri, Steven Kao, Antonio De Maio, Ashkaun Shaterian, Todd W. Costantini, Andrew Baird
Publikováno v:
Experimental lung research, vol 41, iss 3
PurposeThe human c2orf40 gene encodes a candidate tumor suppressor called Esophageal Cancer-Related Gene-4 (ECRG4) that is a cytokine-like epigenetically-regulated protein that is characteristically downregulated in cancer, injury, inflammation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f3e2c18fbc2d70c3323ac5826d965c
https://europepmc.org/articles/PMC4524537/
https://europepmc.org/articles/PMC4524537/
Autor:
Rab K. Prinjha, Casey E. Romanoski, Joshua D. Stender, Karmel A. Allison, Christopher Benner, David F. Tough, Minna U. Kaikkonen, Christopher K. Glass, Sven Heinz, Nathanael J. Spann, Hyun B. Chun
Publikováno v:
Molecular cell, vol 51, iss 3
Recent studies suggest a hierarchical model in which lineage-determining factors act in a collaborative manner to select and prime cell-specific enhancers, thereby enabling signal-dependent transcription factors to bind and function in a cell-type-sp
Autor:
John R. Yates, Hyun B. Chun, Sherry Niessen, Andrew Baird, Bruce E. Torbett, Heather Hoover, Brian P. Eliceiri, Mike Scott
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 31(12)
The blood–brain barrier (BBB) is a multicellular vascular structure separating blood from the brain parenchyma that is composed of endothelial cells with tight intercellular junctions, surrounded by a basal lamina, astrocytes, and pericytes. Previo
Autor:
Andrew Baird, S. Kao, Brian P. Eliceiri, Raul Coimbra, Ashkaun Shaterian, David M. Cauvi, A. DeMaio, Hyun B. Chun, Todd W. Costantini
Publikováno v:
Journal of Surgical Research. 179:339