Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Hyun‐Jung Cho"'
Autor:
Jesse A. Rudd-Schmidt, Adrian W. Hodel, Tahereh Noori, Jamie A. Lopez, Hyun-Jung Cho, Sandra Verschoor, Annette Ciccone, Joseph A. Trapani, Bart W. Hoogenboom, Ilia Voskoboinik
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Cytotoxic T lymphocytes (CTLs) eliminate virus-infected and cancerous cells by secreting the pore-forming protein (perforin) and pro-apoptotic serine proteases (granzymes). Here authors show that two mechanisms protect the membranes of CTLs from disr
Externí odkaz:
https://doaj.org/article/0b570a4b9b4f425cbf44500be5992740
Publikováno v:
Cells, Vol 11, Iss 19, p 2977 (2022)
Cross-talk between astrocytes and microglia plays an important role in neuroinflammation and central sensitization, but the manner in which glial cells interact remains less well-understood. Herein, we investigated the role of dual immunoglobulin dom
Externí odkaz:
https://doaj.org/article/d5d919920c0146bf8637bb6b0535e0ec
Autor:
Emma McHugh, Olivia M. S. Carmo, Adam Blanch, Oliver Looker, Boyin Liu, Snigdha Tiash, Dean Andrew, Steven Batinovic, Andy J. Y. Low, Hyun-Jung Cho, Paul McMillan, Leann Tilley, Matthew W. A. Dixon
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) to the surface of infected red blood cells (RBCs) via membranous organelles, known as the Maurer’s clefts. We d
Externí odkaz:
https://doaj.org/article/039e9446a57547709d035256d1ed16e8
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1134 (2021)
T cells are key immune cells involved in the pathogenesis of several diseases, rendering them important therapeutic targets. Although drug delivery to T cells is the subject of continuous research, it remains challenging to deliver drugs to primary T
Externí odkaz:
https://doaj.org/article/5e8aa0a7a70a4f638f6259f2c162c271
Autor:
Tebo Maseko, Frank Rowland Dunshea, Kate Howell, Hyun-Jung Cho, Leni Rose Rivera, John Barton Furness, Ken Ng
Publikováno v:
Nutrients, Vol 6, Iss 6, Pp 2478-2492 (2014)
Dietary effects of organic Se supplementation in the form of Se-enriched Agaricus bisporus mushroom on ileal mucosal permeability and antioxidant selenoenzymes status in heat induced oxidative stress in rats were evaluated. Acute heat stress (40 °C,
Externí odkaz:
https://doaj.org/article/8c405f1099a8436d8967940d4b0284be
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129972 (2015)
The worldwide prevalence of metabolic diseases, including obesity and diabetes, is increasing. Mitochondrial dysfunction is recognized as a core feature of these diseases. Emerging evidence also suggests that defects in mitochondrial biogenesis, numb
Externí odkaz:
https://doaj.org/article/76782b3c46dd49119552662cbec3d03d
Autor:
Linda J. Fothergill, Brid Callaghan, Leni R. Rivera, TinaMarie Lieu, Daniel P. Poole, Hyun-Jung Cho, David M. Bravo, John B. Furness
Publikováno v:
Nutrients, Vol 8, Iss 10, p 623 (2016)
TRPA1 is a ligand-activated cation channel found in the intestine and other tissues. Components of food that stimulate TRPA1 receptors (phytonutrients) include allyl isothiocyanate, cinnamaldehyde and linalool, but these may also act at other recepto
Externí odkaz:
https://doaj.org/article/63dc9148cb764ee78f6e89d358f149ea
Autor:
Do-Hyun Nam, Byong Chang Jeong, Sunghoon Kim, Jung-Il Lee, Seong Il Seo, Ho Jun Seol, Min Chul Park, Hee Jin Cho, Hyun Jung Cho, Joung Eun Lim, Kyeung Min Joo, Hye Won Lee
Due to the innate high metastatic ability of renal cell carcinoma (RCC), many patients with RCC experience local or systemic relapses after surgical resection. A deeper understanding of the molecular pathogenesis underlying advanced RCC is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7de60f755b849ed968ad890c5248d1
https://doi.org/10.1158/1541-7786.c.6539346
https://doi.org/10.1158/1541-7786.c.6539346
Autor:
Do-Hyun Nam, Byong Chang Jeong, Sunghoon Kim, Jung-Il Lee, Seong Il Seo, Ho Jun Seol, Min Chul Park, Hee Jin Cho, Hyun Jung Cho, Joung Eun Lim, Kyeung Min Joo, Hye Won Lee
PDF file - 53K, Kaplan-Meier graphs representing the probability of cumulative overall survival (OS) in patients with papRCCs stratified according to Tpl2 level in their primary tumors. For TCGA data, high, moderate and low expression were designated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e335364b46d63de41bd419387f5635
https://doi.org/10.1158/1541-7786.22509609
https://doi.org/10.1158/1541-7786.22509609
Autor:
Do-Hyun Nam, Byong Chang Jeong, Sunghoon Kim, Jung-Il Lee, Seong Il Seo, Ho Jun Seol, Min Chul Park, Hee Jin Cho, Hyun Jung Cho, Joung Eun Lim, Kyeung Min Joo, Hye Won Lee
PDF file - 34K, Tpl2 silencing delayed cell cycle progression in human ccRCC Caki-1 cells. *P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff36700c21c759173c61d4c887a70f
https://doi.org/10.1158/1541-7786.22509606
https://doi.org/10.1158/1541-7786.22509606