Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Hyug Moo, Kwon"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Primary cilia on the surface of eukaryotic cells serve as sensory antennas for the reception and transmission in various cell signaling pathways. They are dynamic organelles that rapidly form during differentiation and cell cycle
Externí odkaz:
https://doaj.org/article/bc815ca100d24104aae14ad3b7c7cb0a
Autor:
Laxman Manandhar, Raghbendra Kumar Dutta, Pradeep Devkota, Arun Chhetri, Xiaofan Wei, Channy Park, Hyug Moo Kwon, Raekil Park
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Calcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation, differentiation, and motility. The involvement of calcium in diverse metabolic pathways has been sugges
Externí odkaz:
https://doaj.org/article/b32217acb2234f5ab512c12ab4492cfa
Autor:
Hyun Park, Sang Min Lee, Su Ji Jeong, Yeong Cheon Kweon, Go Woon Shin, Whi Young Kim, Whaseon Lee-Kwon, Chan Young Park, Hyug Moo Kwon
Publikováno v:
Cells, Vol 13, Iss 19, p 1614 (2024)
Human coronaviruses (HCoVs) modify host proteins to evade the antiviral defense and sustain viral expansion. Here, we report tonicity-responsive enhancer (TonE) binding protein (TonEBP) as a cellular target of HCoVs. TonEBP was cleaved into N-termina
Externí odkaz:
https://doaj.org/article/b27a5768a6b149adac96c6d1d059513b
Autor:
Raghbendra Kumar Dutta, Joon No Lee, Yunash Maharjan, Channy Park, Seong-Kyu Choe, Ye-Shih Ho, Hyug Moo Kwon, Raekil Park
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background Lysosomes are a central hub for cellular metabolism and are involved in the regulation of cell homeostasis through the degradation or recycling of unwanted or dysfunctional organelles through the autophagy pathway. Catalase, a per
Externí odkaz:
https://doaj.org/article/067ba67b1b244640b7815c216390c186
Autor:
Yunash Maharjan, Raghbendra Kumar Dutta, Jinbae Son, Xiaofan Wei, Channy Park, Hyug Moo Kwon, Raekil Park
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Autophagy is an intracellular degradation process crucial for homeostasis. During autophagy, a double-membrane autophagosome fuses with lysosome through SNARE machinery STX17 to form autolysosome for degradation of damaged organel
Externí odkaz:
https://doaj.org/article/d173f7d58ece41f0b65708a262f7fe4c
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Microglia are brain-resident myeloid cells involved in the innate immune response and a variety of neurodegenerative diseases. In macrophages, TonEBP is a transcriptional cofactor of NF-κB which stimulates the transcription of pr
Externí odkaz:
https://doaj.org/article/26c6d89745af4ba292427dc62acc5e3e
Autor:
Hyun Je Kang, Hyun Park, Eun Jin Yoo, Jun Ho Lee, Soo Youn Choi, Whaseon Lee-Kwon, Kyoo-young Lee, Jin-Hoe Hur, Jeong Kon Seo, Jae Sun Ra, Eun-A. Lee, Kyungjae Myung, Hyug Moo Kwon
Publikováno v:
iScience, Vol 19, Iss , Pp 177-190 (2019)
Summary: Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA replication. PCNA polyubiquitination is critical for the maintenance of genomic in
Externí odkaz:
https://doaj.org/article/14a94c35bac0452abc34bf283bd79d85
Autor:
Hwan Hee Lee, Seung Min An, Byeong Jin Ye, Jun Ho Lee, Eun Jin Yoo, Gyu Won Jeong, Hyun Je Kang, Assim A. Alfadda, Sun Woo Lim, Jiyoung Park, Whaseon Lee-Kwon, Jae Bum Kim, Soo Youn Choi, Hyug Moo Kwon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Activation of thermogenic beige adipocytes within white adipose tissue increases energy expenditure. Here, the authors show that expression of TonEBP in adipocytes is increased when mice are fed a high fat diet and that it suppresses expression of be
Externí odkaz:
https://doaj.org/article/c910c758701b4d8199d390804df2fbb8
Autor:
Jun Ho Lee, Jae Hee Suh, Hyun Je Kang, Soo Youn Choi, Seok Won Jung, Whaseon Lee-Kwon, Soo-Ah Park, Hajin Kim, Byeong Jin Ye, Eun Jin Yoo, Gyu Won Jeong, Neung Hwa Park, Hyug Moo Kwon
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102926- (2020)
Background: High recurrence and chemoresistance drive the high mortality in hepatocellular carcinoma (HCC). Although cancer stem cells are considered to be the source of recurrent and chemoresistant tumors, they remain poorly defined in HCC. Tonicity
Externí odkaz:
https://doaj.org/article/a706beb6d2f84c6d9b63185fc4d568d2
Autor:
Eun Jin Yoo, Hwan Hee Lee, Byeong Jin Ye, Jun Ho Lee, Chae Young Lee, Hyun Je Kang, Gyu Won Jeong, Hyun Park, Sun Woo Lim, Whaseon Lee-Kwon, Hyug Moo Kwon, Soo Youn Choi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
TonEBP is a key transcriptional activator in macrophages with an M1 phenotype. High expression of TonEBP is associated with many inflammatory diseases. Heme oxygenase-1 (HO-1), a stress-inducible protein, is induced by various oxidative and inflammat
Externí odkaz:
https://doaj.org/article/849a9e515675445ca0f1ab678106a267