Zobrazeno 1 - 10
of 1 834
pro vyhledávání: '"Hypoxia inducible factor-1 alpha"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis sativa. It has therapeutic effects in different paradigms of brain injury, acting as a neuroprotectant. As oxidative stress is a primary risk factor for brain
Externí odkaz:
https://doaj.org/article/5ff0d1c4f6c84debb3fde1fae2afed69
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107537- (2024)
Externí odkaz:
https://doaj.org/article/70cd9ac076e64113852e003d6a37dc78
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 234-251 (2024)
The hypoxic microenvironment is an essential characteristic of most malignant tumors. Notably, hypoxia-inducible factor-1 alpha (HIF-1α) is a key regulatory factor of cellular adaptation to hypoxia, and many critical pathways are correlated with the
Externí odkaz:
https://doaj.org/article/300424bef78f417d810da6b82f0ac9b6
Autor:
Jirong Yan, Zhichao Xi, Jiaying Guo, Lin Xu, Xueyang Sun, Wanjing Sha, Milin Liu, Shenyu Zhao, Enrui Dai, Yu Xu, Hongxi Xu, Huiyan Qu
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background Ventricular remodeling is the adaptive process in which the heart undergoes changes due to stress, leading to heart failure (HF). The progressive decline in cardiac function is considered to contribute to intestinal barrier impair
Externí odkaz:
https://doaj.org/article/e83f2ec17e4f4da18d88e1cc18c3383f
Autor:
Hasan Cagri Yildirim, Hicran Anik, Deniz Ates Ozdemir, Rashad Ismayilov, Arif Akyildiz, Kerim Cayiroz, Fahri Ceyhan, Oguzalp Kavruk, Deniz Can Guven, Ozturk Ates, Alp Usubutun, Zafer Arik
Publikováno v:
Biomolecules & Biomedicine (2024)
This study addresses the gap in understanding the prognostic relevance of hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in metastatic cervical squamous cell carcinoma (SCC) patients undergoing anti-vascular endothelial growth factor-based
Externí odkaz:
https://doaj.org/article/0a6679b01dca4c8a82ddcef55b98579d
Publikováno v:
环境与职业医学, Vol 40, Iss 5, Pp 491-499 (2023)
BackgroundThe exposure to diesel particulate matter (DPM) and its polycyclic aromatic hydrocarbons (PAH) is closely related to the morbidity and mortality of ischemic heart disease (IHD). However, it is unclear what key components and targets of DPM
Externí odkaz:
https://doaj.org/article/79d8eb0f4cb147bd97f49b3f4145affb
Autor:
Jennifer M. Noto, M. Blanca Piazuelo, Judith Romero-Gallo, Alberto G. Delgado, Giovanni Suarez, Konstantina Akritidou, Miguel Girod Hoffman, Juan Carlos Roa, Cormac T. Taylor, Richard M. Peek
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTHelicobacter pylori-induced inflammation is the strongest known risk factor for gastric adenocarcinoma. Hypoxia-inducible factor-1 (HIF-1α) is a key transcriptional regulator of immunity and carcinogenesis. To examine the role of this mediat
Externí odkaz:
https://doaj.org/article/5ca1554c76e54c8382886b3806ff21b3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ziqi Yang, Biyan Ni, Tian Zhou, Zijing Huang, Hong Zhou, Yang Zhou, Shiya Lin, Chang He, Xialin Liu
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1532 (2023)
Hypoxia-induced retinal neovascularization is a leading cause of blindness worldwide. Oxygen-induced retinopathy (OIR) mouse, a well-established angiogenesis model, has been extensively used to evaluate the effect of anti-angiogenic agents through in
Externí odkaz:
https://doaj.org/article/8bbf40bb349c4649a7448e513793509d