Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Hypoxia Pathway"'
Autor:
Culiat, Cymbeline a, ⁎⁎, 1, Soni, Dharmendra b, Malkes, William a, Wienhold, Mark a, Zhang, Linghua Harris c, Henry, Everett c, Dragan, Magdalena c, Kar, Swagata d, Angeles, Dana Marguerite a, Eaker, Shannon a, Biswas, Roopa b, ⁎, 1
Publikováno v:
In Biochemical and Biophysical Research Communications January 2025 744
Akademický článek
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Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Oncogenic Ras mutations are highly prevalent in hematopoietic malignancies. However, it is difficult to directly target oncogenic RAS proteins for therapeutic intervention. We have developed a Drosophila acute myeloid leukemia model induced by human
Externí odkaz:
https://doaj.org/article/5d25a49f49b6465a86a66f4465f680cd
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Qiang Wei, Peng Zhang, Chong Chen, Jiapeng Zhang, Tianhai Lin, Ping Han, Lu Qi, Lu Yang, Ping Tan, Jiajia Du, Ailing Zhong, Yiyun Wang, Jingyao Chen, Yu Liu, Manli Wang, Jian Wang, Zhanying Bi, Qiyong Gong
Publikováno v:
Oncogene. 40:6081-6092
There are unmet clinical needs for novel therapeutic targets and drugs for bladder cancer. Majority of previous work relied on limited bladder cancer cell lines, which could not well represent the tumor heterogeneity and pathology of this disease. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbe5d2b870b4a203ab162714ee2a0b6
https://doi.org/10.1038/s41388-021-01999-9
https://doi.org/10.1038/s41388-021-01999-9
Autor:
Shiva Moein, Kobra Moradzadeh, Shaghayegh Haghjooy Javanmard, Seyed Mahdi Nasiri, Yousof Gheisari
Publikováno v:
Journal of Research in Medical Sciences, Vol 25, Iss 1, Pp 84-84 (2020)
Background: In vitro models are common tools in nephrology research. However, their validity has rarely been scrutinized. Materials and Methods: Considering the critical role of transforming growth factor (TGF)-β and hypoxia pathways in kidney fibro
Externí odkaz:
https://doaj.org/article/a6afa02a08bb41a4a0987900f00e43ea
Autor:
Peipei Gao, Ting Peng, Qin Yang, Wencheng Ding, Canhui Cao, Shitong Lin, Wenhua Zhi, Peng Wu, Ling Xi, Ping Wu
Publikováno v:
OncoTargets and therapy
Peipei Gao,1 Ting Peng,1 Shitong Lin,1 Wenhua Zhi,1 Canhui Cao,1 Ping Wu,1 Ling Xi,1,2 Peng Wu,1,2 Qin Yang,3 Wencheng Ding1,2 1Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Department of Obstetrics and Gynecology, Ton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdd04df7104bf91b58d6766a8255ba5
http://europepmc.org/articles/PMC8286154
http://europepmc.org/articles/PMC8286154
Autor:
Nermeen S. Afifi, Bassem M. Raafat, Ebtehal M. Ismail, Walaa F. Alsanie, Amira M. Gamal-Eldeen, Fayez Althobaiti, Houry M. Baghdadi
Publikováno v:
Molecular & Cellular Toxicology. 17:111-121
Oral tongue squamous cell carcinoma (OTSCC) is a popular aggressive malignancy of the oral cavity. Despite advances in OTSCC therapy, the overall 5-year survival rate is low. The tumor microenvironment resistance factors lead to chemotherapy failure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2fb573095fb91c7c8b2e69136459c6
https://doi.org/10.1007/s13273-021-00117-w
https://doi.org/10.1007/s13273-021-00117-w
Autor:
Jung Won Shin, Ki-Young Jung, Dohyun Han, Jung hun Lee, Tae Joon Kim, Da Hye Lee, Kwang Hyun Baek, Hyeyoon Kim, Jin Sun Jun, Jun Sang Sunwoo, Jung Ick Byun
Publikováno v:
Sleep Medicine. 75:448-455
Objective/Background We performed bioinformatic analysis of proteomic data to identify the biomarkers of restless legs syndrome (RLS) and provide insights into the putative pathomechanisms, including iron deficiency, inflammation, and hypoxic pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4723a3aa5f1855e4236fb3d2c8606664
https://doi.org/10.1016/j.sleep.2020.09.002
https://doi.org/10.1016/j.sleep.2020.09.002
Autor:
Huan Zhao, Yi-Jing Li, Jinxiang Zhang, Hai Huang, Yun-Wei Zhang, Run-Lei Du, Wen-Ming Pan, Xiao-Dong Zhang, Xiao-Fei Zhang, Peng Xu, Hui Wang, Guoliang Wang, Kun-Peng Huang
Publikováno v:
Hepatology (Baltimore, Md.)
Background and Aims Hepatic ischemia‐reperfusion (IR) injury is a major complication of liver transplantation, resection, and hemorrhagic shock. Hypoxia is a key pathological event associated with IR injury. MicroRNA‐210 (miR‐210) has been char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1ccb9cd7d4003112f0b296b8ec76d6
http://europepmc.org/articles/PMC7818437
http://europepmc.org/articles/PMC7818437