Early application of Mdivi-1 protects kidney in rats against uncontrolled hemorrhagic shock

Autor: FANG He, SHE Han, LI Tao, LIU Liangming, ZHU Yu, WU Yue, HU Yi

Publikováno v: Di-san junyi daxue xuebao, Vol 43, Iss 6, Pp 467-472 (2021)

Objective To determine the protective effect of early application of Mdivi-1, an inhibitor of mitochondrial division, on the kidneys of rats with uncontrolled hemorrhagic shock after maintaining hypotensive resuscitation. Methods A total of 128 SD ra

Externí odkaz: https://doaj.org/article/930ec6fe5eb04cbf831a8257a141bf87

Use of intrathoracic pressure regulation therapy in breathing patients for the treatment of hypotension secondary to trauma

Autor: Victor A. Convertino, Brent A. Parquette, David A. Wampler, Craig A. Manifold, David A. Lindstrom, Lori L. Boland, Nathan T. Burkhart, Keith G. Lurie, Charles J. Lick

Publikováno v: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 25, Iss 1, Pp 1-7 (2017)

Abstract Background Intrathoracic pressure regulation (IPR) therapy has been shown to increase blood pressure in hypotensive patients. The potential value of this therapy in patients with hypotension secondary to trauma with bleeding is not well unde

Externí odkaz: https://doaj.org/article/17ccc511be994a6b8d3701c0a89f9b88

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The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats

Autor: Paul Van Slyke, Esther de Groot, Matijs van Meurs, Anoek L I van Leeuwen, Nicole A M Dekker, Joris J. T. H. Roelofs, Marc G. Vervloet, Charissa E. van den Brom

Publikováno v: Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-18 (2021)
Intensive Care Medicine Experimental, 9(1):23. Springer Science + Business Media
van Leeuwen, A L I, Dekker, N A M, van Slyke, P, de Groot, E, Vervloet, M G, Roelofs, J J T H, van Meurs, M & van den Brom, C E 2021, ' The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats ', Intensive Care Medicine Experimental, vol. 9, no. 1, 23, pp. 23 . https://doi.org/10.1186/s40635-021-00389-5
Intensive Care Medicine Experimental, 9(1):23. SpringerOpen
Intensive Care Medicine Experimental

Background Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular leakage.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cf1c32efa488ceaa31948018005cd0
https://doi.org/10.1186/s40635-021-00389-5

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