Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hypoglycemic Agents/pharmacology"'
Autor:
Elena Azzini, Javad Sharifi-Rad, Ahmet Beyatli, Yasaman Taheri, Hafiz Ansar Rasul Suleria, William N. Setzer, Anuj Kumar, Alfred Maroyi, Prabhakar Semwal, Miquel Martorell, G. A. Seitimova, Sakshi Painuli, Oksana Sytar, Balakyz Yeskaliyeva, Bahare Salehi, Natália Martins
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c76e7770e1cb61be1b55d8533431a56
http://link.springer.com/article/10.1186/s12906-020-03033-z
http://link.springer.com/article/10.1186/s12906-020-03033-z
Publikováno v:
Cells
Cells, Vol 10, Iss 1095, p 1095 (2021)
Cells, Vol 10, Iss 1095, p 1095 (2021)
5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most commonly used pharmacological modulators of AMPK activity. The majority of early studies on the role of AMPK, both in the physiological regulation of metabolism and in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaf70488006988fb844a4a694beb3de
https://doi.org/10.3390/cells10051095
https://doi.org/10.3390/cells10051095
Publikováno v:
BASE-Bielefeld Academic Search Engine
Hædersdal, S, Lund, A, Knop, F K & Vilsbøll, T 2018, ' The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes ', Mayo Clinic Proceedings, vol. 93, no. 2, pp. 217-239 . https://doi.org/10.1016/j.mayocp.2017.12.003
Hædersdal, S, Lund, A, Knop, F K & Vilsbøll, T 2018, ' The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes ', Mayo Clinic Proceedings, vol. 93, no. 2, pp. 217-239 . https://doi.org/10.1016/j.mayocp.2017.12.003
Type 2 diabetes is a disease involving both inadequate insulin levels and increased glucagon levels. While glucagon and insulin work together to achieve optimal plasma glucose concentrations in healthy individuals, the usual regulatory balance betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653dac3c7ce511366000f9f40d1ae410
https://doi.org/10.1016/j.mayocp.2017.12.003
https://doi.org/10.1016/j.mayocp.2017.12.003
Autor:
Subhash Kamath, Anthony G. Comuzzie, Stefano La Rosa, Eliana S. Di Cairano, Ana Maria Paez, Alberto O. Chavez, Francesca Casiraghi, Rodolfo Guardado-Mendoza, Paolo Fiorina, Ralph A. DeFronzo, Paul B. Higgins, Fausto Sessa, A.M. Davalli, Gregory A Abrahamian, Giuseppe Daniele, Livio Luzi, Carla Perego, Franco Folli, Amalia Gastaldelli, Francesco Andreozzi, Alessandro Marando, Giovanna Finzi, Patrice A. Frost, Glenn A. Halff, Raul A. Bastarrachea, Andrea Ricotti, Edward J. Dick, Teresa Vanessa Fiorentino
Publikováno v:
JCI insight, vol. 4, no. 20, pp. e93091
The glucagon-like peptide-1 receptor agonist exenatide improves glycemic control by several and not completely understood mechanisms. Herein, we examined the effects of chronic intravenous exenatide infusion on insulin sensitivity, β cell and α cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f072dd0108e820cfaf15ec060579022a
https://serval.unil.ch/resource/serval:BIB_893519A0D48A.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_893519A0D48A.P001/REF.pdf
Autor:
Mehdi Sharifi-Rad, Natália Martins, Solomon Habtemariam, Javad Sharifi-Rad, Bahare Salehi, Shahira M. Ezzat, Mahitab H. El Bishbishy
Publikováno v:
Molecules, Vol 23, Iss 12, p 3334 (2018)
Molecules
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecules
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Diabetes mellitus (DM) is a chronic metabolic disease with high morbimortality rates. DM has two types: type 1, which is often associated with a total destruction of pancreatic beta cells, and non-insulin-dependent or type 2 diabetes mellitus (T2DM),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b7f845bb381f60feaef9ae0d537188
https://www.mdpi.com/1420-3049/23/12/3334
https://www.mdpi.com/1420-3049/23/12/3334
Autor:
Savio Sardinha, Vikas Moudgil, Karl Winckel, Sue Patterson, Terry Stedman, Dan Siskind, Shuichi Suetani, Carmen C.W. Lim, Dylan Flaws, John J. McGrath, Andrea Baker, Anthony W. Russell, Nadia Friend, Steve Kisely
Publikováno v:
BMJ Open
Siskind, D, Friend, N, Russell, A, McGrath, J J, Lim, C, Patterson, S, Flaws, D, Stedman, T, Moudgil, V, Sardinha, S, Suetani, S, Kisely, S, Winckel, K & Baker, A 2018, ' CoMET : A protocol for a randomised controlled trial of co-commencement of METformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia newly commenced on clozapine ', BMJ Open, vol. 8, no. 3, e021000 . https://doi.org/10.1136/bmjopen-2017-021000
Siskind, D, Friend, N, Russell, A, McGrath, J J, Lim, C, Patterson, S, Flaws, D, Stedman, T, Moudgil, V, Sardinha, S, Suetani, S, Kisely, S, Winckel, K & Baker, A 2018, ' CoMET : A protocol for a randomised controlled trial of co-commencement of METformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia newly commenced on clozapine ', BMJ Open, vol. 8, no. 3, e021000 . https://doi.org/10.1136/bmjopen-2017-021000
IntroductionClozapine, while effective in treatment refractory schizophrenia, is associated with significant weight gain, heart disease and increased risk of type 2 diabetes mellitus (T2DM). Although there is evidence for weight loss with metformin f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ed33e61daf7e5b7c96251780a464a8
https://pubmed.ncbi.nlm.nih.gov/29500217
https://pubmed.ncbi.nlm.nih.gov/29500217
Autor:
Regazzi, R.
Publikováno v:
Expert opinion on therapeutic targets, vol. 22, no. 2, pp. 153-160
Diabetes mellitus is a very common metabolic disorder affecting more than 400 million people worldwide. Currently available treatments permit to manage the disease but, in the long term, many patients develop severe micro- and macrovascular complicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::766de2605cdbb8d1af3b93c0e52f811c
https://serval.unil.ch/resource/serval:BIB_7B630506C07A.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_7B630506C07A.P001/REF.pdf
Autor:
Francisco-Javier Bermúdez-Silva, Reinhold Schirmbeck, Piero Marchetti, Livia López-Noriega, Paolo Meda, Nadia Cobo-Vuilleumier, Christian Claude Lachaud, Petra I. Lorenzo, Noelia García Rodríguez, Abdelkrim Hmadcha, Bernat Soria, Marco Bugliani, Esther Fuente-Martin, Katja Stifter, Peter de Haan, Alejandro Martin-Montalvo, Miguel G. Toscano, Luc St-Onge, Géraldine Parnaud, Vincenzo De Tata, Germán Perdomo, Silvana-Yanina Romero-Zerbo, Luis Sánchez Palazón, David Pozo, Benoit R. Gauthier, Kristina Schoonjans, Javier Florido, Irene de Gracia Herrera Gómez, José Manuel Mellado-Gil, Domenico Bosco, Mathurin Baquié
Publikováno v:
Nature Communications, Vol. 9, No 1 (2018) P. 1488
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Repositorio Institucional de la Universidad de Burgos (RIUBU)
Digital.CSIC. Repositorio Institucional del CSIC
Cell Stress
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Repositorio Institucional de la Universidad de Burgos (RIUBU)
Digital.CSIC. Repositorio Institucional del CSIC
Cell Stress
Cobo-Vuilleumier, Nadia et al.
Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell regeneration still have li
Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell regeneration still have li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342a63365fbd42840ce799e55f5e722d
https://archive-ouverte.unige.ch/unige:119421
https://archive-ouverte.unige.ch/unige:119421
Autor:
Marie-Jeanne Richard, Laurent Argaud, Sandrine Lablanche, Cécile Cottet-Rousselle, Thierry Berney, Pierre-Yves Benhamou, Camille Laporte, Eric Fontaine, Frédéric Lamarche
Publikováno v:
Biochimica et Biophysica Acta, Vol. 1847, No 6-7 (2015) pp. 629-639
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2015, 1847 (6-7), pp.629-39. ⟨10.1016/j.bbabio.2015.04.002⟩
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2015, 1847 (6-7), pp.629-39. ⟨10.1016/j.bbabio.2015.04.002⟩
International audience; Deficit in oxygen and energetic substrates delivery is a key factor in islet loss during islet transplantation. Permeability transition pore (PTP) is a mitochondrial channel involved in cell death. We have studied the respecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284c70d7aa72f9100d0259f1d6147062
https://doi.org/10.1016/j.bbabio.2015.04.002
https://doi.org/10.1016/j.bbabio.2015.04.002
Autor:
Laura J. McCulloch, Sam D. Stephen, Claudia Guida, Anne Clark, Davide Basco, Reshma Ramracheya, Mahdieh Godazgar, Charlotte Baker, Duan Chen, Jiawen Dong
Publikováno v:
Diabetes, Obesity & Metabolism
Diabetes, obesity & metabolism, vol. 20, no. 3, pp. 571-581
Diabetes, obesity & metabolism, vol. 20, no. 3, pp. 571-581
Aims The gut hormone peptide tyrosine tyrosine (PYY) is critical for maintaining islet integrity and restoring islet function following Roux‐en‐Y gastric bypass (RYGB). The expression of PYY and its receptors (NPYRs) in islets has been documented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808c8a806d7d046674617780d0f9070f
https://pubmed.ncbi.nlm.nih.gov/28892258
https://pubmed.ncbi.nlm.nih.gov/28892258