Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Hypertrophy/remodeling"'
Autor:
J. Silva Enciso
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 16 (2020)
Externí odkaz:
https://doaj.org/article/9dc96e13716e47c0b7dbf8326088e8c7
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 20, Iss 2, Pp 42-45 (2018)
Special antihypertensive therapy was combined with a prelimenary (6 months) and more pronouced approach of the left ventricle myocardial mass and of the left ventricule index as well as of the systolic and diastolic functions to those in healthy peop
Externí odkaz:
https://doaj.org/article/a8aa8f9dc05c4dd7aa0408e55e68eac1
Autor:
Mengping Chen, Chen Gao, Jiayu Yu, Shuxun Ren, Menglong Wang, R. Max Wynn, David T. Chuang, Yibin Wang, Haipeng Sun
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 11 (2019)
Background Branched‐chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic impact of targeting BCAA catabolic flux under pathological conditions remains understudied.
Externí odkaz:
https://doaj.org/article/69949587b6874b07964e711bd621a596
Autor:
Jie Li, Brandon A. Kemp, Nancy L. Howell, James Massey, Krzysztof Mińczuk, Qiao Huang, Mahendra D. Chordia, R. Jack Roy, James T. Patrie, Giovanni E. Davogustto, Christopher M. Kramer, Frederick H. Epstein, Robert M. Carey, Heinrich Taegtmeyer, Susanna R. Keller, Bijoy K. Kundu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 4 (2019)
Background Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (S
Externí odkaz:
https://doaj.org/article/a109b40e233242ae8d4ca90b331b09f1
Autor:
Qinghang Meng, Bidur Bhandary, Hanna Osinska, Jeanne James, Na Xu, Kritton Shay‐Winkler, James Gulick, Monte S. Willis, Cynthia Lander, Jeffrey Robbins
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 9 (2017)
BackgroundCardiac stress can trigger production of a 40‐kDa peptide fragment derived from the amino terminus of the cardiac myosin‐binding protein C. Cardiac stress, as well as cMyBP‐C mutations, can trigger production of 1 such truncated prote
Externí odkaz:
https://doaj.org/article/dbc27fe9e550438e858ae6824cb461f1
Autor:
Kate L. Weeks, Antonella Ranieri, Agnieszka Karaś, Bianca C. Bernardo, Alexandra S. Ashcroft, Chris Molenaar, Julie R. McMullen, Metin Avkiran
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 4 (2017)
BackgroundClass IIa histone deacetylase (HDAC) isoforms such as HDAC5 are critical signal‐responsive repressors of maladaptive cardiomyocyte hypertrophy, through nuclear interactions with transcription factors including myocyte enhancer factor‐2.
Externí odkaz:
https://doaj.org/article/12b9573ea8a745f5910fce6be9340fe2
Autor:
Julio A. Chirinos, Scott R. Akers, Lien Trieu, Harry Ischiropoulos, Paschalis‐Thomas Doulias, Ali Tariq, Izzah Vasim, Maheswara R. Koppula, Amer Ahmed Syed, Haideliza Soto‐Calderon, Raymond R. Townsend, Thomas P. Cappola, Kenneth B. Margulies, Payman Zamani
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 10 (2016)
BackgroundStable plasma nitric oxide (NO) metabolites (NOM), composed predominantly of nitrate and nitrite, are attractive biomarkers of NO bioavailability. NOM levels integrate the influence of NO‐synthase‐derived NO production/metabolism, dieta
Externí odkaz:
https://doaj.org/article/94b9b05eabcf438ba962dd230ee05a3f
Autor:
Diederik E. van der Feen, Guido P. L. Bossers, Tim R Eijgenraam, Rudolf A. de Boer, Anne-Marie C. Koop, Herman H W Silljé, Quint A. J. Hagdorn, Rolf M. F. Berger, Arnold Piek
Publikováno v:
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 136(6):H1552-H1557. AMER PHYSIOLOGICAL SOC
For indexing cardiac measures in small animal models, tibia length (TL) is a recommended surrogate for body weight (BW) that aims to avoid biases because of disease-induced BW changes. However, we question if indexing by TL is mathematically correct.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87eb17e756948c9f0a5c1dd3efa495e5
https://research.rug.nl/en/publications/61611fef-c935-4cb6-bfbf-cf8abc824986
https://research.rug.nl/en/publications/61611fef-c935-4cb6-bfbf-cf8abc824986
Autor:
Brandon A. Kemp, Christopher M. Kramer, R. Jack Roy, Qiao Huang, Heinrich Taegtmeyer, Giovanni Davogustto, James T. Patrie, Robert M. Carey, Nancy L. Howell, Frederick H. Epstein, Susanna R. Keller, Bijoy Kundu, James C. Massey, Mahendra D. Chordia, Krzysztof Mińczuk, Jie Li
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (S
Autor:
Kentaro Ejiri, Toru Miyoshi, Hajime Kihara, Yoshiki Hata, Toshihiko Nagano, Atsushi Takaishi, Hironobu Toda, Seiji Nanba, Yoichi Nakamura, Satoshi Akagi, Satoru Sakuragi, Taro Minagawa, Yusuke Kawai, Nobuhiro Nishii, Soichiro Fuke, Masaki Yoshikawa, Kazufumi Nakamura, Hiroshi Ito, Tetsuya Sato, Hiroyasu Sugiyama, Michio Imai, Naoki Gotoh, Tomonori Segawa, Toshiyuki Noda, Masatoshi Koshiji
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Effects of sodium‐glucose cotransporter 2 inhibitors on reducing hospitalization for heart failure have been reported in randomized controlled trials, but their effects on patients with heart failure with preserved ejection fraction ( HF