Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Hyperprogressive disease"'
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 6343-6355 (2024)
Hyperprogressive disease (HPD) is described as the unexpected rapid growth of a tumour accompanied by a decline in performance status. While immune checkpoint inhibitors (ICIs) have improved outcomes in advanced melanoma, HPD remains a significant ch
Externí odkaz:
https://doaj.org/article/9619d3fa219746919d3b619b3382c9e8
Autor:
Ya-Zhou Wang, Mao-Zhen Peng, Yao-Lin Xu, Ying Ying, Lin-Hui Tang, Hua-Xiang Xu, Jun-Yi He, Liang Liu, Wen-Quan Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Pancreatic cancer is among the most immune-resistant tumor types due to its unique tumor microenvironment and low cancer immunogenicity. Single-agent immune modulators have thus far proven clinically ineffective. However, a growing body of e
Externí odkaz:
https://doaj.org/article/b392760ffae84c7686bb3f0d5fcc1b9c
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTImmune checkpoint inhibitors (ICIs) have emerged as a promising therapeutic option for large cell neuroendocrine carcinoma (LCNEC). However, various studies have suggested a potential risk of hyperprogressive disease (HPD) in patients receivi
Externí odkaz:
https://doaj.org/article/4bdbddadbc0142e580911cf85e32913c
Autor:
Henry Jeon, BSc, Keith Mackenzie, DO
Publikováno v:
JAAD Case Reports, Vol 47, Iss , Pp 57-60 (2024)
Externí odkaz:
https://doaj.org/article/8f3d1a90578a4357a9c354daa00936fc
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHyperprogressive disease (HPD) is a novel pattern of paradoxically rapid tumor progression, which often leads to early death, mostly in the first 2 months of treatment with immune checkpoint inhibitors (ICIs). Currently, there is no validat
Externí odkaz:
https://doaj.org/article/c0c72bb6854141e2b51d09d816c0fbb9
Publikováno v:
Romanian Journal of Internal Medicine, Vol 62, Iss 1, Pp 33-43 (2024)
Background: Hyperprogressive disease (HPD) can be described as an accelerated increase in the growth rate of tumors combined with rapid clinical deterioration observed in a subset of cancer patients undergoing immunotherapy, specifically with immune
Externí odkaz:
https://doaj.org/article/c638d21f49d04360a225b751ad0a5abb
Publikováno v:
Biomedical Papers, Vol 167, Iss 4, Pp 376-384 (2023)
Background. Hyperprogressive disease (HPD) is a new phenomenon that has emerged in the immunotherapy era. HPD is defined as a rapid tumour growth with detrimental effect on the patient condition and disease course. The management and treatment follow
Externí odkaz:
https://doaj.org/article/4afbc63683ce4b01b1fd8c2398437510
Autor:
Kosuke Masuda, Yoshiaki Nagai, Hikari Amari, Hiroki Tahara, Yuki Maeda, Jun Shiihara, Hiromitsu Ohta, Masahiro Hiruta, Yasuhiro Yamaguchi
Publikováno v:
Thoracic Cancer, Vol 14, Iss 31, Pp 3161-3165 (2023)
Abstract Hyperprogressive disease (HPD) is a novel progressive pattern that occurs after immune checkpoint inhibitor (ICI) administration. Here, a 74‐year‐old woman who had undergone right lower lobectomy for lung cancer received curative chemora
Externí odkaz:
https://doaj.org/article/e909103745de484da881f5fc0ee1eb6e
Autor:
Yaping Long, Wenyu Yang, Yibing Bai, Haitao Tao, Fan Zhang, Lijie Wang, Bo Yang, Di Huang, Xiao Han, Yi Hu
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Hyper progressive disease (HPD) describes the phenomenon that patients can’t benefit from immunotherapy but cause rapid tumor progression. HPD is a particular phenomenon in immunotherapy but lacks prediction methods. Our study a
Externí odkaz:
https://doaj.org/article/a0f89b33c7774d32a4eefae12a9e9db5
Autor:
Jiajie He, Rui Zou, Liqing Kang, Lingzi Yu, Peng Wang, Yang Shao, Junheng Liang, Depei Wu, Zhengming Jin, Changju Qu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Chimeric antigen receptor T-cell therapy (CAR-T) has been widely applied in the clinical practice of relapse/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) due to its promising effects. Hyperprogressive disease (HPD) has gained attention for
Externí odkaz:
https://doaj.org/article/24ddf2eff3fa4b34b2c9f71339a0eea4