Zobrazeno 1 - 10
of 4 106
pro vyhledávání: '"Hyperexcitability"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Epilepsies are disorders of the brain characterised by an imbalance in electrical activity, linked to a disruption in the excitation and inhibition of neurons. Progress in the epilepsy research field has been hindered by the lack of an appro
Externí odkaz:
https://doaj.org/article/49a6013cdc49493cab9ff88382b1a5b1
Autor:
Ja-Hae Kim, Minhee Jeong, Hohyeon Kim, Ji-Hye Kim, Ji Woong Ahn, Boyoung Son, Kang-Ho Choi, Seungsoo Chung, Jungwon Yoon
Publikováno v:
Brain Stimulation, Vol 17, Iss 5, Pp 1048-1059 (2024)
Background and objectives: The effects of noninvasive focused magnetothermal brain stimulation using magnetic nanoparticles (MNPs) on post-stroke motor deficits and metabolic dormancy in subacute ischemic injury are not well-established. This study e
Externí odkaz:
https://doaj.org/article/189f9bf2934845348d46e54639c0dd51
Autor:
Manoj Raghavan, Jared Pilet, Chad Carlson, Christopher T. Anderson, Wade Mueller, Sean Lew, Candida Ustine, Priyanka Shah-Basak, Vahab Youssofzadeh, Scott A. Beardsley
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Methods to quantify cortical hyperexcitability are of enormous interest for mapping epileptic networks in patients with focal epilepsy. We hypothesize that, in the resting state, cortical hyperexcitability increases firing-rate correlations
Externí odkaz:
https://doaj.org/article/2f1401be805245c7b8f2de23aee17ac1
Autor:
Sung-Ju Hsueh, Chin-Hsien Lin, Ni-Chung Lee, Tung-Ming Chang, Sung-Pin Fan, Wan-De Huang, Yea-Huey Lin, Li-Kai Tsai, Yin-Hsiu Chien, Ming-Jen Lee, Wuh-Liang Hwu, Hsueh Wen Hsueh, Chih-Chao Yang
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background To investigate the peripheral nervous system involvement in S sialidosis with typical features of myoclonus, seizure, and giant waves in somatosensory evoked potentials suggesting hyperexcitability in the central nervous system. M
Externí odkaz:
https://doaj.org/article/0abe53ded10c4a81bffb009dfc2f1d65
Autor:
Eva C. Bach, Jeff L. Weiner
Publikováno v:
Neurobiology of Stress, Vol 32, Iss , Pp 100665- (2024)
With the recent rise in the rate of alcohol use disorder (AUD) in women, the historical gap between men and women living with this condition is narrowing. While there are many commonalities in how men and women are impacted by AUD, an accumulating bo
Externí odkaz:
https://doaj.org/article/02c3f172d062417db20688d6482bb99d
Autor:
Sterre van der Veen, Hendriekje Eggink, Jan Willem J. Elting, Deborah Sival, Corien C. Verschuuren-Bemelmans, Tom J. de Koning, Marina A.J. Tijssen
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106555- (2024)
Progressive myoclonus ataxia (PMA) is a rare clinical syndrome characterized by the presence of progressive myoclonus and ataxia, and can be accompanied by mild cognitive impairment and infrequent epileptic seizures. This is the first study to descri
Externí odkaz:
https://doaj.org/article/e8508a22114248478e2942ea76cd0dd8
Autor:
Sebastian Moguilner, Rubén Herzog, Yonatan Sanz Perl, Vicente Medel, Josefina Cruzat, Carlos Coronel, Morten Kringelbach, Gustavo Deco, Agustín Ibáñez, Enzo Tagliazucchi
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background The hypothesis of decreased neural inhibition in dementia has been sparsely studied in functional magnetic resonance imaging (fMRI) data across patients with different dementia subtypes, and the role of social and demographic hete
Externí odkaz:
https://doaj.org/article/791a0b5ece6d460fb80e6340b8a8387e
Autor:
Naoki Ikegaya, Honoka Nakamura, Yutaro Takayama, Yohei Miyake, Takahiro Hayashi, Masaki Sonoda, Mitsuru Sato, Kensuke Tateishi, Jun Suenaga, Masao Takaishi, Yu Kitazawa, Misako Kunii, Hiroki Abe, Tomoyuki Miyazaki, Tetsuaki Arai, Manabu Iwasaki, Takayuki Abe, Tetsuya Yamamoto
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION The use of anti‐epileptic drugs (AEDs) in degenerative dementia (DD) remains uncertain. We aimed to evaluate the association of early AED administration with subsequent DD occurrence. METHODS Using a large nationwide database,
Externí odkaz:
https://doaj.org/article/a9e3e85dd375488d89766625af530235
Autor:
Wei Sun, Fan Yang, Yan Wang, Yan Yang, Rui Du, Xiao‐Liang Wang, Zhi‐Xin Luo, Jun‐Jie Wu, Jun Chen
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract Neuropathic pain can occur during the prediabetic stage, even in the absence of hyperglycemia. The presence of prediabetic neuropathic pain (PDNP) poses challenges to the management of individuals with prediabetes. However, the mechanisms un
Externí odkaz:
https://doaj.org/article/d3ad4f436a27471a83c067c4951455dd
Publikováno v:
Frontiers in Dementia, Vol 3 (2024)
IntroductionNeuronal hyperexcitability and neuroinflammation are thought to occur at early stages in a range of neurodegenerative diseases. Neuroinflammation, notably activation of microglia, has been identified as a potential prodromal marker of dem
Externí odkaz:
https://doaj.org/article/3030d2f922534e369de89646a4b2567f