Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hyperandrogenic Disorders Throughout the Lifespan and Into the Next Generation"'
Publikováno v:
Journal of the Endocrine Society
The magnitude and direction to which cardio-metabolic and reproductive aberrations may disproportionately impact diverse populations of women with PCOS are relevant yet unclear. The uncertainty stems, in part, from heterogeneity in PCOS diagnostic cr
Publikováno v:
Journal of the Endocrine Society
Polycystic ovary syndrome (PCOS) is a complex disorder associated with obesity, sleep apnea, and disordered eating. We aimed to assess whether COVID19 related social isolation affects lifestyle and weight control in women with PCOS. We performed an o
Publikováno v:
Journal of the Endocrine Society
Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that affects between 5- 10% of women of reproductive age. It is currently considered a complex and multifactorial disease with metabolic, cardiovascular implications and re
Publikováno v:
Journal of the Endocrine Society
Background: The main feature of polycystic ovary syndrome (PCOS) is hyperandrogenism, adipocytes hypertrophy and chronic low-grade inflammation. It is known that PCOS is closely linked to functional dysfunction in adipose tissue, which in turn are co
Autor:
Flavia Tosi, Maria E. Street, Matteo Migazzi, Francesca Cirillo, Marco Dauriz, Cecilia Catellani, Michela Villani, Paolo Moghetti
Publikováno v:
Journal of the Endocrine Society
Context: High mobility group box 1 (HMGB1) is a nuclear constitutive and highly conserved mammalian protein which shows several important physiologic functions, playing a crucial role in local and systemic inflammation. It also seems to be implicated
Publikováno v:
Journal of the Endocrine Society
Introduction: At times clinicians wonder why a subject’s Anti-Mullerian Hormone (AMH) does not correlate to the antral follicle count (AFC). AMH is secreted as a full-length protein and undergoes proteolytic cleavage at amino acid 451 to become bio
Autor:
Julia K. Bosdou, Christina Bothou, Djuro P Macut, Dimitrios G. Goulis, Panagiotis Anagnostis, Sarantis Livadas, Rodis Paparodis, Andrea Dunaif
Publikováno v:
Journal of the Endocrine Society
Background/Aims: Polycystic ovary syndrome (PCOS) is associated with disordered carbohydrate metabolism and an increased risk for T2D. However, there are limited data on the magnitude of this risk. Furthermore, 50-80% of women with PCOS are obese and
Publikováno v:
Journal of the Endocrine Society
Women with polycystic ovary syndrome (PCOS) exhibit reduced skeletal muscle insulin-mediated glucose uptake. Altered muscle mass may affect insulin resistance (IR) and inflammation, thereby potentially aggravating reproductive status including ovulat
Publikováno v:
Journal of the Endocrine Society
Background: The exact association between clinical and biochemical hyperandrogenism (HA) is heterogeneous and cannot be ascertained, especially in normoandrogenic women. Aim: Evaluate any association between clinical HA phenotypes and biochemical par
Autor:
Jessica S Lim, Brittany Y Jarrett, Kathleen M. Hoeger, Adam T Evans, Heidi Vanden Brink, Marla E. Lujan
Publikováno v:
Journal of the Endocrine Society
Introduction: Women with polycystic ovary syndrome (PCOS) have an increased incidence of sleep disturbances compared to healthy women. Circulating melatonin (MEL) is elevated in women with PCOS, thought to reflect an increased daytime and blunted pea