Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hyounkoo Han"'
Autor:
Mingyun Kim, Doyeon Kim, Yongho Jang, Hyounkoo Han, Seonock Lee, Hyungwon Moon, Jungho Kim, Hyuncheol Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1194 (2023)
In anticancer therapy, combination therapy has been suggested as an alternative to the insufficient therapeutic efficacy of single therapy. Among combination therapies, combination chemo- and photodynamic therapy are actively investigated. However, p
Externí odkaz:
https://doaj.org/article/c082e7948bd144a8b65b0c60ee49b9bd
Autor:
Hyeong Min Kim, Hyounkoo Han, Hye Kyoung Hong, Ji Hyun Park, Kyu Hyung Park, Hyuncheol Kim, Se Joon Woo
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 655 (2021)
In this study, Retina-RPE-Choroid-Sclera (RCS) and RPE-Choroid-Sclera (CS) were prepared by scraping them off neural retina, and using the Ussing chamber we measured the average time–concentration values in the acceptor chamber across five isolated
Externí odkaz:
https://doaj.org/article/11e9ee33ef0c4f9ab11fb44be30fbcf1
Autor:
Henry T. Hsueh, Yoo-Chun Kim, Ian Pitha, Matthew D. Shin, Cynthia A. Berlinicke, Renee Ti Chou, Elizabeth Kimball, Julie Schaub, Sarah Quillen, Kirby T. Leo, Hyounkoo Han, Amy Xiao, Youngwook Kim, Matthew Appell, Usha Rai, HyeYoung Kwon, Patricia Kolodziejski, Laolu Ogunnaike, Nicole M. Anders, Avelina Hemingway, Joan L. Jefferys, Abhijit A. Date, Charles Eberhart, Thomas V. Johnson, Harry A. Quigley, Donald J. Zack, Justin Hanes, Laura M. Ensign
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 647 (2021)
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP low
Externí odkaz:
https://doaj.org/article/3232c89326b24142bbf27c0ff670b9ea
Autor:
Yongwhan Choi, Hyounkoo Han, Sangmin Jeon, Hong Yeol Yoon, Hyuncheol Kim, Ick Chan Kwon, Kwangmeyung Kim
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 974 (2020)
The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetrati
Externí odkaz:
https://doaj.org/article/6d8d971bfa6442269cf85663aec57061
Autor:
Tuo Meng, Jinhua Zheng, Min Chen, Yang Zhao, Hadi Sudarjat, Aji Alex M.R., Vineet Kulkarni, Yumin Oh, Shiyu Xia, Zheng Ding, Hyounkoo Han, Nicole Anders, Michelle A. Rudek, Woon Chow, Walter Stark, Laura M. Ensign, Justin Hanes, Qingguo Xu
Publikováno v:
Science Advances. 9
Topical corticosteroid eye drop is the mainstay for preventing and treating corneal graft rejection. While the frequent topical corticosteroid use is associated with risk of intraocular pressure (IOP) elevation and poor patient compliance that leads
Autor:
Charles G. Eberhart, Cynthia A. Berlinicke, Patricia Kolodziejski, Henry T. Hsueh, Nicole M. Anders, Kirby T. Leo, Matthew B. Appell, Renee Ti Chou, Hyounkoo Han, Hye Young Kwon, Ian Pitha, Avelina Hemingway, Yoo Chun Kim, Usha Rai, Justin Hanes, Matthew D. Shin, Laura M. Ensign, Donald J. Zack
Publikováno v:
Drug Deliv Transl Res
While eye drops are the most common ocular dosage form, eye drops for treating diseases of the posterior segment (retina, choroid, optic nerve) have yet to be developed. In glaucoma, eye drops are used extensively for delivering intraocular pressure
Autor:
Kwangmeyung Kim, Minkyu Seo, Yongho Jang, Hyuncheol Kim, Hyounkoo Han, Doyeon Kim, Jong Bum Lee
Publikováno v:
Journal of Controlled Release. 322:346-356
Nanotechnology-based combination therapies, especially chemo-gene therapy, have been spotlighted as promising alternatives for cancer therapy. However, only a small amount of systemically administered nanomedicines reach the tumor site by the enhance
Autor:
Matthew B. Appell, Ian Pitha, Renee Ti Chou, Abhijit A. Date, Laura M. Ensign, Charles G. Eberhart, Matthew D. Shin, Cynthia A. Berlinicke, Nicole M. Anders, Usha Rai, Hyounkoo Han, Joan L. Jefferys, Henry T. Hsueh, Avelina Hemingway, Elizabeth C. Kimball, Sarah Quillen, Thomas V. Johnson, Justin Hanes, Amy Xiao, Harry A. Quigley, Donald J. Zack, Yoo Chun Kim, Kirby T. Leo, Laolu Ogunnaike, Patricia Kolodziejski, Julie Schaub, Youngwook Kim, Hye Young Kwon
Publikováno v:
Pharmaceutics, Vol 13, Iss 647, p 647 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP low
Autor:
Hong Yeol Yoon, Kwangmeyung Kim, Hyounkoo Han, Yongwhan Choi, Sangmin Jeon, Hyuncheol Kim, Ick Chan Kwon
Publikováno v:
Pharmaceutics, Vol 12, Iss 974, p 974 (2020)
Pharmaceutics
Volume 12
Issue 10
Pharmaceutics
Volume 12
Issue 10
The dense extracellular matrix (ECM) in heterogeneous tumor tissues can prevent the deep tumor penetration of drug-loaded nanoparticles, resulting in a limited therapeutic efficacy in cancer treatment. Herein, we suggest that the deep tumor penetrati
Autor:
Howon Seo, Hyuncheol Kim, Sujung Hong, Hyounkoo Han, Minkyu Seo, Jae Hwan Lee, Pilhan Kim, Hongkeun Yoo, Doyeon Kim, Jin Wook Chung, Hak Jong Lee, Jingu Lee, Hyungwon Moon
Publikováno v:
Theranostics
Transarterial chemoembolization (TACE) is an image-guided locoregional therapy used for the treatment of patients with primary or secondary liver cancer. However, conventional TACE formulations are rapidly dissociated due to the instability of the em