Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Hyoungseok Ju"'
Autor:
Leon Tejwani, Youngseob Jung, Hiroshi Kokubu, Sowmithra Sowmithra, Luhan Ni, Changwoo Lee, Benjamin Sanders, Paul J. Lee, Yangfei Xiang, Kimberly Luttik, Armand Soriano, Jennifer Yoon, Junhyun Park, Hannah H. Ro, Hyoungseok Ju, Clara Liao, Sofia Massaro Tieze, Frank Rigo, Paymaan Jafar-Nejad, Janghoo Lim
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
Protein aggregation is a hallmark of many neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). Although mutations in TARDBP, encoding transactive response DNA-binding protein 43 kDa (TDP-43), account for less than 1% of all ALS
Externí odkaz:
https://doaj.org/article/3422673f0c504358a6b5a37951131574
Autor:
Hyoungseok Ju, Byungho Lim, Minjin Kim, Yong Sung Kim, Woo Ho Kim, Chunhwa Ihm, Seung-Moo Noh, Dong Soo Han, Hang-Jong Yu, Bo Youl Choi, Changwon Kang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 12, Pp 1340-1347 (2009)
PTPRCAP (CD45-AP) is a positive regulator of protein tyrosine phosphatase PTPRC (CD45), which activates Src family kinases implicated in tumorigenesis. Single-nucleotide polymorphism (SNP) rs869736 located at position -309 of the PTPRCAP promoter was
Externí odkaz:
https://doaj.org/article/561243839b3740d68293ecbe447e0d61
Autor:
Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim
PDF file - 376K, Inhibition rates (IR) of tumor growth (A) and response rates at IR30 (chemosensitivity) (B). The IRs and IR30 of a single bevacizumab or cetuximab regimen were significantly less than those of the other four combination regimens (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a473ba7dea4671299522a34854e2ed29
https://doi.org/10.1158/1078-0432.22444835
https://doi.org/10.1158/1078-0432.22444835
Autor:
Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim
Purpose: Methods for predicting individual responsiveness to targeted chemotherapy are urgently needed, considering the frequent resistance and extremely high cost.Experimental Design: A chemosensitive single-nucleotide polymorphism (SNP) discovery s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a587e29c208d9c2c2dddc813d4808d
https://doi.org/10.1158/1078-0432.c.6520304.v1
https://doi.org/10.1158/1078-0432.c.6520304.v1
Autor:
Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim
PDF file - 2.6MB, Genome-wide association with in vitro chemosensitivity to targeted regimens: FRB (A), FXB (B), FRC (C), and FXC (D). Association of SNPs with the inhibition ratio was tested by linear regression analysis. P-values of < 0.001 are ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cafa4041221aa1402e52d723d9e475
https://doi.org/10.1158/1078-0432.22444832
https://doi.org/10.1158/1078-0432.22444832
Autor:
Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim
PDF file - 181K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a952807bf24703e5efe6f6711ccc44e
https://doi.org/10.1158/1078-0432.22444826.v1
https://doi.org/10.1158/1078-0432.22444826.v1
Autor:
Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim
PDF file - 1.4MB, Cell viability measured by MTT assay in transfected CRC clones (a. DFNB31 rs2274159; b. ANXA11 rs1049550; c. LINS1 rs11247226) treated with FRC (a), FRB (b), and FXB (c), respectively. Bold font, P < 0.05. FRC, FOLFIRI + cetuximab;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd00e457c27686519a684a341d57439
https://doi.org/10.1158/1078-0432.22444829.v1
https://doi.org/10.1158/1078-0432.22444829.v1
Autor:
Kimberly Luttik, Leon Tejwani, Hyoungseok Ju, Terri Driessen, Cleo J. L. M. Smeets, Chandrakanth Reddy Edamakanti, Aryaan Khan, Joy Yun, Puneet Opal, Janghoo Lim
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including Purkinje cells (PCs) in the cerebellum. Previous studies have de
Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including Purkinje cells (PCs) in the cerebellum. Previous studies have de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39dd286ebf28812ebd50893921f03c50
https://doi.org/10.1101/2021.10.21.465333
https://doi.org/10.1101/2021.10.21.465333
Autor:
Luttik, Kimberly, Tejwani, Leon, Hyoungseok Ju, Driessen, Terri, Smeets, Cleo J. L. M., Edamakanti, Chandrakanth Reddy, Khan, Aryaan, Joy Yun, Opal, Puneet, Janghoo Lim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/23/2022, Vol. 119 Issue 34, p1-12, 26p