Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hyoung-Goo Park"'
Autor:
Harim Kim, Young-Jin Chun, Sung Woo Park, Hyoung-Goo Park, Donghak Kim, Vitchan Kim, Myung-A. Cho, Rowoon Lee
Publikováno v:
Archives of Biochemistry and Biophysics. 671:27-34
The pathogenic fungus Candida albicans contains genes encoding five fatty acid hydroxylases belonging to the CYP52 family in its genome. Our previous study reported that CYP52A21 demonstrated typical omega-hydroxylation of lauric acid (Kim D, Cryle M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb11553c28080557b80e86d8c32da9a
https://doi.org/10.1016/j.abb.2019.06.002
https://doi.org/10.1016/j.abb.2019.06.002
Autor:
Hyoung-Goo Park, Harim Kim, Kyoung Sang Cho, Yejin Lee, Donghak Kim, Vitchan Kim, Myung-A. Cho, Thien-Hoang Ho, Im-Soon Lee
Publikováno v:
Chemico-Biological Interactions. 289:90-97
Human cytochrome P450 2B6 is an important hepatic enzyme for the metabolism of xenobiotics and clinical drugs. Recently, more attention has been paid to P450 2B6 because of the increasing number of drugs it metabolizes. It has been known to interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efad79d19800f44f9383f3b340f59596
https://doi.org/10.1016/j.cbi.2018.04.029
https://doi.org/10.1016/j.cbi.2018.04.029
Publikováno v:
Journal of Microbiology and Biotechnology. 27:983-989
NADPH-P450 reductase (NPR) transfers electrons from NADPH to cytochrome P450 and heme oxygenase enzymes to support their catalytic activities. This protein is localized within the endoplasmic reticulum membrane and utilizes FMN, FAD, and NADPH as cof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b4785b44c108e1f194437b9e6181ec
https://doi.org/10.4014/jmb.1701.01028
https://doi.org/10.4014/jmb.1701.01028
Autor:
Donghak Kim, Thien-Kim Le, Chul-Ho Yun, Joo-Hwan Kim, Young-Ran Lim, Hyoung-Goo Park, Songhee Han, Ga-Young Lee
Publikováno v:
Biomolecules & Therapeutics. 25:171-176
Streptomyces avermitilis produces clinically useful drugs such as avermectins and oligomycins. Its genome contains approximately 33 cytochrome P450 genes and they seem to play important roles in the biosynthesis of many secondary metabolites. The SAV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d9319043547f813aa0c1ec6bf119ecf
https://doi.org/10.4062/biomolther.2016.182
https://doi.org/10.4062/biomolther.2016.182
Autor:
Young-Jin Chun, Dabin Jeong, Chul-Ho Yun, Lin-Woo Kang, Joo-Hwan Kim, Donghak Kim, Young-Ran Lim, Songhee Han, Tan-Viet Pham, Hyoung-Goo Park
Publikováno v:
Biochemical and Biophysical Research Communications. 482:902-908
Streptomyces avermitilis is an actinobacterium known to produce clinically useful macrolides including avermectins. CYP107L2 from S. avermitilis shares a high sequence similarity with the PikC (CYP107L1) from S. venezuelae. To elucidate the structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e9ff7b0b479fa5d9e2a142627c4bad
https://doi.org/10.1016/j.bbrc.2016.11.131
https://doi.org/10.1016/j.bbrc.2016.11.131
Publikováno v:
Journal of toxicology and environmental health. Part A. 81(12)
Humans possess three cytochrome P450 enzymes in the 2A subfamily (2A6, 2A7, and 2A13). P450 2A13 is mainly expressed in the human trachea and lung, whereas P450 2A6 is found in human liver. The P450 2A13 enzyme may be considered as the primary enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea8326b4898eb6a1a403cc303a17dfd
https://pubmed.ncbi.nlm.nih.gov/29652224
https://pubmed.ncbi.nlm.nih.gov/29652224
Autor:
Hwayoun Lee, Donghak Kim, Hyoung-Goo Park, Yeo-Jung Kwon, Beom Joon Kim, Young-Jin Chun, Seul-Ong Ohk
Publikováno v:
Protein Expression and Purification. 114:89-94
Malassezia globosa is pathogenic fungus that causes skin disorders including dandruff in humans. Many yeast cytochrome CYP enzymes are involved in the biosynthesis of sterols and are considered major targets of azole antifungal agents. Here, we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d4b99f7aaf3e2d5cfb6b9e8479a021
https://doi.org/10.1016/j.pep.2015.07.002
https://doi.org/10.1016/j.pep.2015.07.002
Publikováno v:
Veterinární medicína. 60:202-207
The objective of this study was to evaluate the in vitro efficacy of a topical skin cream containing a mixture of emu oil, jojoba oil, avocado oil, and tea tree oil against the canine skin pathogens Staphylococcus pseudintermedius and Malassezia pach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5c92bc4f07819cbfd310eb1e24f55a
https://doi.org/10.17221/8108-vetmed
https://doi.org/10.17221/8108-vetmed
Autor:
Hyoung-Goo Park, In-Hyeok Kim, Young-Jin Chun, Songhee Han, Young-Ran Lim, Donghak Kim, Mi-Jung Ko, Chul-Ho Yun
Publikováno v:
Biomolecules & Therapeutics
P450 1A2 is responsible for the metabolism of clinically important drugs and the metabolic activation of environmental chemicals. Genetic variations of P450 1A2 can influence its ability to perform these functions, and thus, this study aimed to chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7e20a97b0b22b3e25fbe7bfea56d55
http://europepmc.org/articles/PMC4354321
http://europepmc.org/articles/PMC4354321
Autor:
Yejin Lee, Young-Ran Lim, Hyoung-Goo Park, Vitchan Kim, Myung-A. Cho, Donghak Kim, Dabin Jeong
Publikováno v:
Drug metabolism and pharmacokinetics. 33(1)
The human cytochrome P450 2J2 is involved in several metabolic reactions, including the oxidation of important therapeutics and epoxidation of endogenous arachidonic acid. At least ten genetic variations of P450 2J2 have been identified, but their ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b158346d24ba12428a8b3c0763fb293
https://pubmed.ncbi.nlm.nih.gov/29223463
https://pubmed.ncbi.nlm.nih.gov/29223463