Zobrazeno 1 - 10
of 3 382
pro vyhledávání: '"Hyoung Kim"'
Autor:
Haineng Xu, Sarah B. Gitto, Gwo-Yaw Ho, Sergey Medvedev, Kristy Shield-Artin, Hyoung Kim, Sally Beard, Yasuto Kinose, Xiaolei Wang, Holly E. Barker, Gayanie Ratnayake, Wei-Ting Hwang, Ryan J. Hansen, Bryan Strouse, Snezana Milutinovic, Christian Hassig, Matthew J. Wakefield, Cassandra J. Vandenberg, Clare L. Scott, Fiona Simpkins
Publikováno v:
iScience, Vol 27, Iss 7, Pp 109978- (2024)
Summary: High-grade serous ovarian cancers (HGSOCs) with homologous recombination deficiency (HRD) are initially responsive to poly (ADP-ribose) polymerase inhibitors (PARPi), but resistance ultimately emerges. HGSOC with CCNE1 amplification (CCNE1am
Externí odkaz:
https://doaj.org/article/1ed5cdda17844d2e8fc282a3b801056b
Autor:
Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A. Greenberg, Lauren Schwartz, Neil Johnson, Robert B. Scharpf, Gordon B. Mills, Rugang Zhang, Victor E. Velculescu, Eric J. Brown, Fiona Simpkins
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Patients with ovarium cancer frequently develop resistance to platinum chemotherapy and PARP inhibitors (PARPi). Here, the authors show that the combination of PARP and ATR inhibitors increases the therapeutic response in PARPi and platinum resistant
Externí odkaz:
https://doaj.org/article/cc35bbdbfeb9477db7745da1954cd683
Autor:
Haineng Xu, Erin George, Yasuto Kinose, Hyoung Kim, Jennifer B. Shah, Jasmine D. Peake, Benjamin Ferman, Sergey Medvedev, Thomas Murtha, Carter J. Barger, Kyle M. Devins, Kurt D’Andrea, Bradley Wubbenhorst, Lauren E. Schwartz, Wei-Ting Hwang, Gordon B. Mills, Katherine L. Nathanson, Adam R. Karpf, Ronny Drapkin, Eric J. Brown, Fiona Simpkins
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100394- (2021)
Summary: CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCN
Externí odkaz:
https://doaj.org/article/317f0b4f67b94645ac9dda7eac42892d
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The white-blooded Antarctic icefishes is a representative organism that survive under the stenothermal conditions of the Southern Ocean without the hemoglobin genes. To compensate for inefficient oxygen transport, distinct feature
Externí odkaz:
https://doaj.org/article/eec1b73f525f4ed79cece769222498a3
Autor:
Jeong Bong Kim, Jae Hwan Cho, Jae Woo Park, Jin Hoon Park, Seung Hyun Baek, Tae Hyoung Kim, Sehan Park, Chang Ju Hwang, Dong-Ho Lee
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Risk factors for local recurrence in patients with metastatic spinal cord compression (MSCC) has not been clearly investigated. So, the purpose of this study was to identify risk factors causing local recurrence following surgerie
Externí odkaz:
https://doaj.org/article/11c0d645adff4f7eb5ddbaed33f66b50
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 287, Iss , Pp 117249- (2024)
The escalating impacts of climate change, particularly ocean acidification and warming, are pivotal stressors for marine ecosystems and have profound effects on biota in polar regions. This study investigated the immunological responses of the Antarc
Externí odkaz:
https://doaj.org/article/e918fec9b894416c84e4030584952b80
Autor:
Ho Chu, Hee, Hyoung Kim, Jin, Ha Kim, Gun, Yeon Kim, So, Jung Lee, So, Jin Won, Hyung, Moon Shin, Yong
Publikováno v:
In European Journal of Radiology December 2024 181
Autor:
Sung Kim, Jun, Bin Bae, Jong, Won Han, Ji, Jong Oh, Dae, Wan Suh, Seung, Hyoung Kim, Jae, Woong Kim, Ki
Publikováno v:
In NeuroImage: Clinical 2023 37
Autor:
Young-soon Bae, Dong-Su Kim, Hyo Jung Seo, Je-Un Han, Hyung Jin Yoon, Jung Jin Hwang, Ju Jin Kim, Byung Hyo Woo, Hyo Jin Kim, Yoo Soon Jang, Seok Chang Han, Woong Hee Kim, Do Goo Kang, Hyun Jin Seo, Soo Young Lee, Sang June Jeon, Jungyu Yi, Jeongwoo Lee, Il Hyeok Seo, Se Hyun Kim, Woo Hyoung Kim, Na Hyung Park, Myeng Hyun Lee, Sung June Bae, Seung Hoon Lee, Gyu Ho Cho, Seong Han Kim, Seong Hwan Moon, Min Kyu Lee, Jae Won Choi, Kyu Young Lee, Dong Seok Huh, Dong Woo Kim, Kyung June Min, Hyoung Min Yoon, Hyunhye Kyung, Jieun Yang, Dasom Na, Sangbong Lee, Jaehwan Han, Yongho Kwak, Sei-Young Lee, Joo Young Nam, Byung-Ho Choi, Young-Kwan Moon, Won Do, Mooyoung Yoo, Sun-Sun Park
Publikováno v:
AAPPS Bulletin, Vol 32, Iss 1, Pp 1-23 (2022)
Abstract Boron neutron capture therapy (BNCT) has been attracting interest as a new radiation modality for cancer therapy because it can selectively destroy cancer cells while maintaining the healthy state of surrounding normal cells. Many experiment
Externí odkaz:
https://doaj.org/article/7c9fee6dd61b495f8d05f0e01390ec52
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract The geriatric nutritional risk index (GNRI) is a nutrition-related risk assessment tool and has been used in various clinical settings. The relationship between body mass index (BMI) and the associated risk of diabetic retinopathy (DR) remai
Externí odkaz:
https://doaj.org/article/c167ce2ae61f4bcf9abf3df9deee4ca0