Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Hyoung Gon Ko"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract O-GlcNAcylation is a posttranslational modification where N-acetylglucosamine (O-GlcNAc) is attached and detached from a serine/threonine position by two enzymes: O-GlcNAc transferase and O-GlcNAcase. In addition to roles in diabetes and can
Externí odkaz:
https://doaj.org/article/f244f89df39441bf880703a7d96ab253
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Pathological pain is caused by abnormal activity in the neural circuit that transmits nociceptive stimuli. Beyond homeostatic functions, astrocytes actively participate in regulating synaptic transmission as members of tripartite synapses. T
Externí odkaz:
https://doaj.org/article/fc45c964baac4fe7b6e143a37ce2634a
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-4 (2023)
Abstract Itch is a distinctive sensation that causes a specific affection and scratching reaction. The anterior cingulate cortex (ACC) has been linked to itch sensation in numerous studies; however, its precise function in processing pruritic inputs
Externí odkaz:
https://doaj.org/article/d791ac6f0e194ba9a98bd4d9bfa76ff5
Autor:
Yi Sul Cho, Won Mah, Dong Ho Youn, Yu Shin Kim, Hyoung-Gon Ko, Jin Young Bae, Yun Sook Kim, Yong Chul Bae
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
IntroductionSatellite glial cells (SGCs) that envelop the cell bodies of neurons in sensory ganglia have been shown to both release glutamate, and be activated by glutamate in the context of nociceptive signaling. However, little is known about the s
Externí odkaz:
https://doaj.org/article/6bd5bf2e69814a14ac47eedc535dcc5e
Autor:
Tae-Jun Kim, Yu Gyung Kim, Won Jung, Sungil Jang, Hyoung-Gon Ko, Chan Ho Park, Jin-Seok Byun, Do-Yeon Kim
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1646 (2023)
Oral lichen planus (OLP) is a chronic inflammatory disease that is characterized by the infiltration of T cells into the oral mucosa, causing the apoptosis of basal keratinocytes. OLP is a multifactorial disease of unknown etiology and is not solely
Externí odkaz:
https://doaj.org/article/651d925381ee4ea896164ee11c104ed0
Autor:
Hyoung-Gon Ko
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Lateral habenula (LHb) is a brain region acting as a hub mediating aversive response against noxious, stressful stimuli. Growing evidences indicated that LHb modulates aminergic activities to induce avoidance behavior against nociceptive sti
Externí odkaz:
https://doaj.org/article/9ea3ec06989343189257830dffa79697
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Synaptic proteins play an important role for the regulation of synaptic plasticity. Numerous studies have identified and revealed individual synaptic protein functions using protein overexpression or deletion. In neuropathic pain nociceptive
Externí odkaz:
https://doaj.org/article/761f8e41f7354c25a381da33eb28635d
Autor:
Hyoung-Gon Ko, Jun-Hyeok Choi, Dong Ik Park, SukJae Joshua Kang, Chae-Seok Lim, Su-Eon Sim, Jaehoon Shim, Ji-Il Kim, Siyong Kim, Tae-Hyeok Choi, Sanghyun Ye, Jaehyun Lee, Pojeong Park, Somi Kim, Jeehaeh Do, Jihye Park, Md Ariful Islam, Hyun Jeong Kim, Christoph W. Turck, Graham L. Collingridge, Min Zhuo, Bong-Kiun Kaang
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 748-759 (2018)
Peripheral nerve injury can induce pathological conditions that lead to persistent sensitized nociception. Although there is evidence that plastic changes in the cortex contribute to this process, the underlying molecular mechanisms are unclear. Here
Externí odkaz:
https://doaj.org/article/ab90b55a2eb741d9829cc87725633ded
Autor:
Chae-Seok Lim, Hye Jin Nam, Jaehyun Lee, Dongha Kim, Ja Eun Choi, SukJae Joshua Kang, Somi Kim, Hyopil Kim, Chuljung Kwak, Kyu-Won Shim, Siyong Kim, Hyoung-Gon Ko, Ro Un Lee, Eun-Hae Jang, Juyoun Yoo, Jaehoon Shim, Md Ariful Islam, Yong-Seok Lee, Jae-Hyung Lee, Sung Hee Baek, Bong-Kiun Kaang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 phosphorylation by PKCα was imp
Externí odkaz:
https://doaj.org/article/0d31f3b5d7f647abb2626298419871e9
Autor:
Yi Sul Cho, Sook Kyung Park, Angom Pushparani Devi, Yong Chul Bae, Duk Yoon Kim, Jin Young Bae, Hyoung-Gon Ko
Publikováno v:
Journal of Comparative Neurology. 527:3002-3013
That visceral sensory afferents are functionally distinct from their somatic analogues has been known for a long time but the detailed knowledge of their synaptic connections and neurotransmitters at the first relay nucleus in the spinal cord has bee