Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Hyong-Kyu Kim"'
Autor:
So-Yoon Won, Jung-Jin Park, Soon-Tae You, Jong-A Hyeun, Hyong-Kyu Kim, Byung Kwan Jin, Catriona McLean, Eun-Young Shin, Eung-Gook Kim
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-13 (2022)
Abstract Aggregation of misfolded alpha-synuclein (α-synuclein) is a central player in the pathogenesis of neurodegenerative diseases. Therefore, the regulatory mechanism underlying α-synuclein aggregation has been intensively studied in Parkinson
Externí odkaz:
https://doaj.org/article/ea5257c7141342b589cea8d0d933be1d
Autor:
Eun-Young Shin, Chan-Soo Lee, Cheong-Yong Yun, So-Yoon Won, Hyong-Kyu Kim, Yong Hee Lee, Sahng-June Kwak, Eung-Gook Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95212 (2014)
Non-muscle myosin II (NM II) regulates a wide range of cellular functions, including neuronal differentiation, which requires precise spatio-temporal activation of Rho GTPases. The molecular mechanism underlying the NM II-mediated activation of Rho G
Externí odkaz:
https://doaj.org/article/91946b084b774f389ca6162e6b4ccbc2
Autor:
Hee Jeong Kim, Kina Lee, Kiseo Yoo, Jeong Eun Kim, Chae-Seok Lim, Hyong Kyu Kim, Yong Sook Goo
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S314- (2023)
Externí odkaz:
https://doaj.org/article/4ff0b28f881a414da3f81fecaa50bd37
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Postsynaptic density protein 95 (PSD-95) is a pivotal postsynaptic scaffolding protein in excitatory neurons. Although the transport and regulation of PSD-95 in synaptic regions is well understood, dendritic transport of PSD-95 before synapt
Externí odkaz:
https://doaj.org/article/5246b798f1764e45ac7e0fec46d65c92
Autor:
Jaisan Islam, Elina KC, Kyoung Ha So, Soochong Kim, Hyong Kyu Kim, Yoon Young Park, Young Seok Park
Publikováno v:
Scientific Reports. 13
Posterior hypothalamus (PH), an important part of the descending pain processing pathway, has been found to be activated in trigeminal autonomic cephalalgias. However, there are very few studies conducted and information regarding its implications in
Autor:
Eun-Young Shin, Eun-Yul Cho, Jin-Hee Park, Eung-Gook Kim, Chan-Soo Lee, Han-Byeol Kim, Gun-Wu Lee, Kwang-Seok Oh, Hyong Kyu Kim
Publikováno v:
BMB Reports
Proper targeting of the βPAK-interacting exchange factor (βPIX)/G protein-coupled receptor kinase-interacting target protein (GIT) complex into distinct cellular compartments is essential for its diverse functions including neurite extension and sy
Autor:
Seongkwang Cha, Jungryul Ahn, Yurim Jeong, Yong Hee Lee, Hyong Kyu Kim, Daekee Lee, Yongseok Yoo, Yong Sook Goo
Publikováno v:
Frontiers in Cellular Neuroscience. 16
One of the critical prerequisites for the successful development of retinal prostheses is understanding the physiological features of retinal ganglion cells (RGCs) in the different stages of retinal degeneration (RD). This study used our custom-made
Publikováno v:
Frontiers in Cellular Neuroscience. 16
The trigeminal ganglion (TG) is the primary site of aberration in trigeminal neuralgia (TN), and hence a crucial site where afferent input can be modulated. Here, we postulated that inhibiting TG via optogenetics using flexible optic cannula would di
Publikováno v:
Experimental Neurobiology
Guanine nucleotide exchange factors (GEFs) play multiple functional roles in neurons. In a previous study, we reported that Arhgef4 (Rho guanine nucleotide exchange factor 4) functioned as a negative regulator of the excitatory synaptic function by s
Autor:
Soochong Kim, Elina Kc, Jai Ho Choi, So Yoon Won, Hyeong Cheol Moon, Hyong Kyu Kim, Sang-Hwan Hyun, Jaisan Islam, Kyoung-Ha So, Young Seok Park
Publikováno v:
Journal of Korean Neurosurgical Society
Objective No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2 encoding a fragment of mutant huntingtin (AV