Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Hyon E Choy"'
Autor:
Hyun Uk Kim, Soo Young Kim, Haeyoung Jeong, Tae Yong Kim, Jae Jong Kim, Hyon E Choy, Kyu Yang Yi, Joon Haeng Rhee, Sang Yup Lee
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-15 (2011)
Abstract Although the genomes of many microbial pathogens have been studied to help identify effective drug targets and novel drugs, such efforts have not yet reached full fruition. In this study, we report a systems biological approach that efficien
Externí odkaz:
https://doaj.org/article/e1143f8bb3b5477a890f151fd0b0018a
Autor:
Kwangsoo Kim, Jae Ho Jeong, Daejin Lim, Yeongjin Hong, Hyung-Ju Lim, Geun-Joong Kim, So-ra Shin, Je-Jung Lee, Misun Yun, Robert A Harris, Jung-Joon Min, Hyon E Choy
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor. L-asparaginase (L-ASNase), which primarily converts asparagine to aspartate
Externí odkaz:
https://doaj.org/article/3c08b86bee9840319cb46a8d07a448b4
Autor:
Seung-Hwan Park, Sukho Park, Dong-Yeon Kim, Ayoung Pyo, Richard H Kimura, Ataya Sathirachinda, Hyon E Choy, Jung-Joon Min, Sanjiv Sam Gambhir, Yeongjin Hong
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132976 (2015)
Monobodies are binding scaffold proteins originating from a human fibronectin domain III (Fn3) scaffold that can be easily engineered with specificity and affinity. Human EphA2 (hEphA2) is an early detection marker protein for various tumors includin
Externí odkaz:
https://doaj.org/article/24cf4a55cd474f5ea17afe87e2077416
Autor:
Hee-Chang Jang, Su-Mi Choi, Hee Kyung Kim, Sung-Eun Kim, Seung-Ji Kang, Kyung-Hwa Park, Phil Youl Ryu, Tae-Hoon Lee, Young Ran Kim, Joon Haeng Rhee, Sook-In Jung, Hyon E Choy
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101118 (2014)
ObjectivesThe in vivo efficacy of a cefotaxime-ciprofloxacin combination against Vibrio vulnificus and the effects on rtxA1 expression of commonly used antibiotics are unknown.MethodsIn vitro time-kill studies were performed to evaluate synergism. Fe
Externí odkaz:
https://doaj.org/article/97a95066ab3e4ce8b0039230fa9e10cd
Autor:
Jae-Ho Jeong, Kwangsoo Kim, Daejin Lim, Kwangjoon Jeong, Yeongjin Hong, Vu H Nguyen, Tae-Hyoung Kim, Sangryeol Ryu, Jeong-A Lim, Jae Il Kim, Geun-Joong Kim, Sun Chang Kim, Jung-Joon Min, Hyon E Choy
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e80050 (2014)
Bacterial cancer therapy relies on the fact that several bacterial species are capable of targeting tumor tissue and that bacteria can be genetically engineered to selectively deliver therapeutic proteins of interest to the targeted tumors. However,
Externí odkaz:
https://doaj.org/article/023e15b7802e47c0a85d3e13e17cc3a9
Autor:
Kwangsoo Kim, Jae Ho Jeong, Daejin Lim, Yeongjin Hong, Misun Yun, Jung-Joon Min, Sahng-June Kwak, Hyon E Choy
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60511 (2013)
During the last decade, an increasing number of papers have described the use of various genera of bacteria, including E. coli and S. typhimurium, in the treatment of cancer. This is primarily due to the facts that not only are these bacteria capable
Externí odkaz:
https://doaj.org/article/737876c5c73f44a792979f860102b883
Autor:
Hee-Chang Jang, Seung-Ji Kang, Su-Mi Choi, Kyung-Hwa Park, Jong-Hee Shin, Hyon E Choy, Sook-In Jung, Hong Bin Kim
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49136 (2012)
BackgroundDysfunction of agr, with reduced susceptibility or hetero-resistance to vancomycin, is thought to be associated with a worse outcome of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (MRSAB). However, the difference in agr dy
Externí odkaz:
https://doaj.org/article/e9f8ef881f4842a6a25cef79fa0d273f
Publikováno v:
Mobile DNA. 14
Antimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements. In this study, we identified a strain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b0052f01e136a42280afe8bba32485b
https://doi.org/10.1186/s13100-023-00292-8
https://doi.org/10.1186/s13100-023-00292-8
Supplementary Figure 1 from Genetically Engineered Salmonella typhimurium as an Imageable Therapeutic Probe for Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0492e6d89550fd9b62fc2dc26c243273
https://doi.org/10.1158/0008-5472.22382906
https://doi.org/10.1158/0008-5472.22382906
Supplementary Figure 3 from Genetically Engineered Salmonella typhimurium as an Imageable Therapeutic Probe for Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5193aa77f603324061b91f40944ebfc1
https://doi.org/10.1158/0008-5472.22382900
https://doi.org/10.1158/0008-5472.22382900