Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Hyon‐Seung Yi"'
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 5, Pp 864-881 (2024)
Immunosenescence denotes a state of dysregulated immune cell function characterized by a confluence of factors, including arrested cell cycle, telomere shortening, markers of cellular stress, mitochondrial dysfunction, loss of proteostasis, epigeneti
Externí odkaz:
https://doaj.org/article/8a273f73970a487baf7b2d4dd0784680
Publikováno v:
Endocrinology and Metabolism, Vol 39, Iss 3, Pp 425-444 (2024)
Thyroid cancer is a common endocrine malignancy with increasing incidence globally. Although most cases can be treated effectively, some cases are more aggressive and have a higher risk of mortality. Inhibiting RET and BRAF kinases has emerged as a p
Externí odkaz:
https://doaj.org/article/45be98c55dc940359323e69f315e4528
Autor:
Jingwen Tian, Minchul Song, Kyu Jeong Cho, Ho Yeop Lee, Sang Hyeon Ju, Jung Ryul Lim, Ha Thi Nga, Thi Linh Nguyen, Ji Sun Moon, Hyo Ju Jang, Jung-Mo Hwang, Hyon-Seung Yi
Publikováno v:
Endocrinology and Metabolism, Vol 39, Iss 3, Pp 521-530 (2024)
Background Aging leads to sarcopenia, which is characterized by reduced muscle mass and strength. Many factors, including altered muscle protein turnover, diminished neuromuscular function, hormonal changes, systemic inflammation, and the structure a
Externí odkaz:
https://doaj.org/article/caa0ab03f5b14362bb4092537681944c
Autor:
Joung Youl Lim, Sang-Hyeon Ju, Ji Min Kim, Hyon-Seung Yi, Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku, Kyong Hye Joung
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundUteroglobin is a multifunctional protein with anti-inflammatory properties. Studies have revealed the importance of inflammation in type 2 diabetes mellitus (T2D) pathogenesis. Here, we investigated the relationship between uteroglobin and
Externí odkaz:
https://doaj.org/article/ace60df7cf464a74b21a5e34326389e7
Mitochondrial Stress and Mitokines: Therapeutic Perspectives for the Treatment of Metabolic Diseases
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 1, Pp 1-18 (2024)
Mitochondrial stress and the dysregulated mitochondrial unfolded protein response (UPRmt) are linked to various diseases, including metabolic disorders, neurodegenerative diseases, and cancer. Mitokines, signaling molecules released by mitochondrial
Externí odkaz:
https://doaj.org/article/2ee9baf83d25430e8bdebd751249a79a
Autor:
Ji Hye Han, Kyong Hye Joung, Jun Choul Lee, Ok Soon Kim, Sorim Choung, Ji Min Kim, Yea Eun Kang, Hyon-Seung Yi, Ju Hee Lee, Bon Jeong Ku, Hyun Jin Kim
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 1, Pp 112-121 (2024)
Background Type 2 diabetes mellitus (T2DM) induces endothelial dysfunction and inflammation, which are the main factors for atherosclerosis and cardiovascular disease. The present study aimed to compare the effects of rosuvastatin monotherapy and ros
Externí odkaz:
https://doaj.org/article/fdea9a06fe8f4ad18c149796777819f8
Autor:
Sang-Hyeon Ju, Joung Youl Lim, Minchul Song, Ji Min Kim, Yea Eun Kang, Hyon-Seung Yi, Kyong Hye Joung, Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectivesChronic low-grade inflammation is widely recognized as a pathophysiological defect contributing to β-cell failure in type 2 diabetes mellitus (T2DM). Statin therapy is known to ameliorate CD8+ T cell senescence, a mediator of chronic infla
Externí odkaz:
https://doaj.org/article/eb0702e803e242b78005cbf1dd8d838e
Autor:
Byeong Chang Sim, Yea Eun Kang, Sun Kyoung You, Seong Eun Lee, Ha Thi Nga, Ho Yeop Lee, Thi Linh Nguyen, Ji Sun Moon, Jingwen Tian, Hyo Ju Jang, Jeong Eun Lee, Hyon-Seung Yi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstract Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans. However, the relationships of the senescence an
Externí odkaz:
https://doaj.org/article/5b10246ce29b4e65ba7d5e661f1174d9
Autor:
Young Mi Kang, Bon Seok Koo, Hyon-Seung Yi, Jung Tae Kim, Boyoung Park, Ju Hee Lee, Minho Shong, Yea Eun Kang
Publikováno v:
The Korean Journal of Internal Medicine, Vol 38, Iss 2, Pp 226-237 (2023)
Background/Aims Recent evidence has identified the significance of type 2 iodothyronine deiodinase (DIO2) in various diseases. However, the role of DIO2 polymorphism in metabolic parameters in patients with hypothyroidism is not fully understood. Met
Externí odkaz:
https://doaj.org/article/fe366748f298438ca64224d1f1c33635
Autor:
Ho Yeop Lee, Byeong Chang Sim, Ha Thi Nga, Ji Sun Moon, Jingwen Tian, Nguyen Thi Linh, Sang Hyeon Ju, Dong Wook Choi, Daiki Setoyama, Hyon-Seung Yi
Publikováno v:
Endocrinology and Metabolism, Vol 37, Iss 6, Pp 891-900 (2022)
Background An excess of thyroid hormones in Graves’ disease (GD) has profound effects on systemic energy metabolism that are currently partially understood. In this study, we aimed to provide a comprehensive understanding of the metabolite changes
Externí odkaz:
https://doaj.org/article/246ac2261b21425d8a44ed6762ea0d2d