Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hyoe Inomata"'
Autor:
Tamio Teramoto, Tomohiro Sawa, Satoshi Iimuro, Hyoe Inomata, Takashi Koshimizu, Iori Sakakibara, Katsutoshi Hiramatsu
Publikováno v:
Cardiovascular Therapeutics, Vol 2020 (2020)
Background. Familial hypercholesterolemia (FH) is a genetic disorder characterized by high levels of low-density lipoprotein cholesterol (LDL-C). Because of underdiagnosis, acute coronary syndrome (ACS) is often the first clinical manifestation of FH
Externí odkaz:
https://doaj.org/article/2d059acdfb334e55bfa23834a38283b5
Autor:
Katsutoshi Oda, Daisuke Aoki, Hitoshi Tsuda, Hiroshi Nishihara, Hisanori Aoyama, Hyoe Inomata, Muneaki Shimada, Takayuki Enomoto
Publikováno v:
Cancer scienceREFERENCES. 114(1)
The association between germline BRCA1 and BRCA2 pathogenic variants (mutations: gBRCAm) and ovarian cancer risk is well established. Germline testing alone cannot detect somatic BRCA1/2 pathogenic variants (sBRCAm), which is calculated based on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c309efc74a8d136c298ee6a67489377
https://pubmed.ncbi.nlm.nih.gov/36254756
https://pubmed.ncbi.nlm.nih.gov/36254756
Autor:
Kouji Kajinami, Junichiro Shimauchi, Ikuo Inoue, Marcoli Cyrille, Chen Lu, Hyoe Inomata, Shinji Koba
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: In patients with hyperlipidemia, intolerance to statins presents a challenge in reducing the risk of events associated with cardiovascular disease. This phase 3, randomized, double-blind trial in Japanese patients with statin intolerance aimed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3813b583674fd824913fd795e5b46c49
http://europepmc.org/articles/PMC7242224
http://europepmc.org/articles/PMC7242224
Autor:
Keiko Asao, Junichiro Shimauchi, Junya Ako, Koutaro Yokote, Tamio Teramoto, Kazuo Kitagawa, Yasuhiko Shinmura, Hyoe Inomata, Toshihiko Sugioka
Publikováno v:
Circulation Reports
Background: Evolocumab is the first monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9) approved in Japan for the treatment of patients with familial hypercholesterolemia (FH) and hypercholesterolemia (HC). This study as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d2f6ced0cc756758dd94bf90585f32
http://europepmc.org/articles/PMC7889485
http://europepmc.org/articles/PMC7889485
Autor:
Hyoe Inomata, Chen Lu, Andrew Hamer, Atsushi Hirayama, Arihiro Kiyosue, Tamio Teramoto, Andrea Ruzza, Shizuya Yamashita, Masayuki Yoshida, Marcoli Cyrille
Publikováno v:
Circulation Journal. 83:971-977
Background Treatment with evolocumab reduces mean low-density lipoprotein cholesterol (LDL-C) up to 75% and cardiovascular events by 16% in the first year and 25% thereafter. Methods and Results: Japanese patients with hypercholesterolemia enrolled i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a5cc16b14ec7f8a7b86d42ebd95034
https://doi.org/10.1253/circj.cj-19-0139
https://doi.org/10.1253/circj.cj-19-0139
Autor:
Toru Sugiyama, Nobuhiro Takeshima, Kana Hattori, Junzo Kigawa, Hyoe Inomata, Hitoshi Tsuda, Kosuke Yoshihara, Masahisa Jinushi, Daisuke Aoki, Yoh Watanabe, Takayuki Enomoto
Publikováno v:
Cancer Science
Whether germline (g) breast cancer susceptibility gene (BRCA) mutations are located within or outside the ovarian cancer cluster region (OCCR) (1380‐4062 bp for gBRCA1, and between 3249‐5681 bp and 6645‐7471 bp for gBRCA2) may influence risk va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be80a23179a238e9a91dd47769e47e0
https://pubmed.ncbi.nlm.nih.gov/32495382
https://pubmed.ncbi.nlm.nih.gov/32495382
Autor:
Toru Sugiyama, Kana Hattori, Hyoe Inomata, Daisuke Aoki, Yoh Watanabe, Kosuke Yoshihara, Hitoshi Tsuda, Takayuki Enomoto, Junzo Kigawa, Nobuhiro Takeshima
Publikováno v:
Gynecologic Oncology. 159:342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9390b9ceeb4d5b48d5d942fea9a88d14
https://doi.org/10.1016/j.ygyno.2020.05.632
https://doi.org/10.1016/j.ygyno.2020.05.632
Autor:
Saurabh P Nagar, Kathleen M. Fox, Pratik P. Rane, Yi Qian, Juliana Meyers, Hyoe Inomata, Anne Beaubrun, Kouji Kajinami, Keith L. Davis
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 82(4)
Background This study examined treatment patterns, possible statin intolerance, and incidence of cardiovascular events (CVEs) in 2 cohorts of patients with high cardiovascular risk (i.e., patients with atherosclerotic cardiovascular disease [ASCVD] a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727b8c6ff7b0206d9869eb0723ae6ed7
https://pubmed.ncbi.nlm.nih.gov/29526987
https://pubmed.ncbi.nlm.nih.gov/29526987
Autor:
Masayuki Yoshida, Hyoe Inomata, Marcoli Cyrille, Shizuya Yamashita, Andrea Ruzza, Helina Kassahun, Tamio Teramoto, Arihiro Kiyosue, Yuhui Ma, Atsushi Hirayama
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 81(7)
Background Evolocumab, a fully human monoclonal antibody against PCSK9, significantly reduced low-density lipoprotein-cholesterol (LDL-C) levels in Japanese patients by up to 76% when administered with a statin. We evaluated the efficacy and safety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732050408157e2e1095ff34646827574
https://pubmed.ncbi.nlm.nih.gov/28367845
https://pubmed.ncbi.nlm.nih.gov/28367845
Autor:
Takashi Kohno, Minako Yamaoka-Tojo, Varadarajan Sudhahar, Takashi Ashino, Masuko Ushio-Fukai, Tohru Fukai, Hyoe Inomata, Norifumi Urao, Ronald D McKinney
Publikováno v:
American Journal of Physiology-Cell Physiology. 305:C591-C600
Platelet-derived growth factor (PDGF) stimulates vascular smooth muscle cell (VSMC) migration and neointimal formation in response to injury. We previously identified IQ-domain GTPase-activating protein 1 (IQGAP1) as a novel VEGF receptor 2 binding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9f095f52426573e4784a1e013ffecf
https://doi.org/10.1152/ajpcell.00011.2013
https://doi.org/10.1152/ajpcell.00011.2013