Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hyo Rim Ko"'
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is essential for neuronal development and function, whereas excessive αK40 deacetylation is observed in neurodegenerative disorders including Alzheime
Externí odkaz:
https://doaj.org/article/95c6bc4e3a2c4a87b527d0ba56019dad
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1039-1047 (2020)
Cell biology: deciphering differences between “sibling” proteins A pair of proteins that originate from a common gene exert strikingly different effects on embryonic development as well as tumor growth and progression. RNA transcripts generated f
Externí odkaz:
https://doaj.org/article/66779de78d284bcebd6a60ec68a47ea0
Autor:
Hyo Rim Ko, So Yoon Ahn, Yun Sil Chang, Inwoo Hwang, Taegwan Yun, Dong Kyung Sung, Se In Sung, Won Soon Park, Jee-Yin Ahn
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-15 (2018)
Abstract Background Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have been shown to prevent brain damage and improve neurocognition following intraventricular hemorrhage (IVH). However, the molecular mechanisms underlying the
Externí odkaz:
https://doaj.org/article/8059e8b7d57449d39eaa0a2756b82421
Autor:
Eun-Ju Jin, Hyo Rim Ko, Inwoo Hwang, Byeong-Seong Kim, Jeong-Yun Choi, Kye Won Park, Sung-Woo Cho, Jee-Yin Ahn
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Neurite growth is controlled by a complex molecular signaling network that regulates filamentous actin (F-actin) dynamics at the growth cone. The evolutionarily conserved ezrin, radixin, and moesin family of proteins tether F-actin to the ce
Externí odkaz:
https://doaj.org/article/538f9eccc6944d4ea7f95ddf10f2149e
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6537a7650b40463082856189f68ef18f
Autor:
Hyo Rim Ko, Il-Sun Kwon, Inwoo Hwang, Eun-Ju Jin, Joo-Ho Shin, Angela M Brennan-Minnella, Raymond Swanson, Sung-Woo Cho, Kyung-Hoon Lee, Jee-Yin Ahn
Publikováno v:
eLife, Vol 5 (2016)
Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone
Externí odkaz:
https://doaj.org/article/83f4236ab2ee463daf7a00d5fecd4b0e
Autor:
Inwoo Hwang, Byeong-Seong Kim, Hyo Rim Ko, Seongbong Cho, Ho Yun Lee, Sung-Woo Cho, Dongryeol Ryu, Sungbo Shim, Jee-Yin Ahn
Publikováno v:
Molecular Psychiatry. 27:2030-2041
Cerebellar deficits with Purkinje cell (PCs) loss are observed in several neurologic disorders. However, the underlying mechanisms as to how the cerebellum is affected during development remain unclear. Here we demonstrated that specific inactivation
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Cell Death Discovery
Cell Death Discovery
Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is essential for neuronal development and function, whereas excessive αK40 deacetylation is observed in neurodegenerative disorders including Alzheimer’s dis
Publikováno v:
BMB Reports
ErbB3-binding protein 1 (EBP1) is a multifunctional protein associated with neural development. Loss of Ebp1 leads to upregulation of the gene silencing unit suppressor of variegation 3-9 homolog 1 (Suv39H1)/DNA (cytosine 5)-methyltransferase (DNMT1)
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1039-1047 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
The roles of the two isoforms of ErbB3-binding protein 1 (Ebp1) in cellular function and its regulation in disease and development is a stimulating area in current fields of biology, such as neuroscience, cancer biology, and structural biology. Over