Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Hyo Kyun Chung"'
Autor:
Jingwen Tian, Hyo Kyun Chung, Ji Sun Moon, Ha Thi Nga, Ho Yeop Lee, Jung Tae Kim, Joon Young Chang, Seul Gi Kang, Dongryeol Ryu, Xiangguo Che, Je‐Yong Choi, Masayuki Tsukasaki, Takayoshi Sasako, Sang‐Hee Lee, Minho Shong, Hyon‐Seung Yi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1785-1799 (2022)
Abstract Background Mitochondrial oxidative phosphorylation (OxPhos) is a critical regulator of skeletal muscle mass and function. Although muscle atrophy due to mitochondrial dysfunction is closely associated with bone loss, the biological character
Externí odkaz:
https://doaj.org/article/9642f574119e4bc3998ae75d78625e53
Autor:
Seul Gi Kang, Min Jeong Choi, Saet-Byel Jung, Hyo Kyun Chung, Joon Young Chang, Jung Tae Kim, Yea Eun Kang, Ju Hee Lee, Hyun Jung Hong, Sang Mi Jun, Hyun-Joo Ro, Jae Myoung Suh, Hail Kim, Johan Auwerx, Hyon-Seung Yi, Minho Shong
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102181- (2021)
Summary: Perturbation of mitochondrial proteostasis provokes cell autonomous and cell non-autonomous responses that contribute to homeostatic adaptation. Here, we demonstrate distinct metabolic effects of hepatic metabokines as cell non-autonomous fa
Externí odkaz:
https://doaj.org/article/61fd91c3505d466992b3cc6e208ce269
Autor:
Saet-Byel Jung, Min Jeong Choi, Dongryeol Ryu, Hyon-Seung Yi, Seong Eun Lee, Joon Young Chang, Hyo Kyun Chung, Yong Kyung Kim, Seul Gi Kang, Ju Hee Lee, Koon Soon Kim, Hyun Jin Kim, Cuk-Seong Kim, Chul-Ho Lee, Robert W. Williams, Hail Kim, Heung Kyu Lee, Johan Auwerx, Minho Shong
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
M1-like polarization of macrophages is thought to control adipose inflammation and associated insulin resistance and metabolic syndrome. Here the authors show that macrophage-specific deletion of the OxPhos-related gene Crif1 results in an M1-like ph
Externí odkaz:
https://doaj.org/article/e543088fca854de18576144178eee3f2
Autor:
Jun Hwa Hong, Hyo Kyun Chung, Hye Yoon Park, Kyong-Hye Joung, Ju Hee Lee, Jin Gyu Jung, Koon Soon Kim, Hyun Jin Kim, Bon Jeong Ku, Minho Shong
Publikováno v:
Diabetes & Metabolism Journal, Vol 38, Iss 6, Pp 472-479 (2014)
BackgroundGrowth differentiation factor-15 (GDF15) is a protein that belongs to the transforming growth factor β superfamily. An elevated serum level of GDF15 was found to be associated with type 2 diabetes mellitus (T2DM). T2DM is an inflammatory d
Externí odkaz:
https://doaj.org/article/71787e62c71c4884bc38e823368ed0d0
Autor:
Min Jeong Ryu, Soung Jung Kim, Yong Kyung Kim, Min Jeong Choi, Surendar Tadi, Min Hee Lee, Seong Eun Lee, Hyo Kyun Chung, Saet Byel Jung, Hyun-Jin Kim, Young Suk Jo, Koon Soon Kim, Sang-Hee Lee, Jin Man Kim, Gi Ryang Kweon, Ki Cheol Park, Jung Uee Lee, Young Yun Kong, Chul-Ho Lee, Jongkyeong Chung, Minho Shong
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003356 (2013)
Impaired mitochondrial oxidative phosphorylation (OXPHOS) has been proposed as an etiological mechanism underlying insulin resistance. However, the initiating organ of OXPHOS dysfunction during the development of systemic insulin resistance has yet t
Externí odkaz:
https://doaj.org/article/da0569523536448dbc3b3e6c833bfcda
Publikováno v:
Biochemical and Biophysical Research Communications. 558:57-63
Nonalcoholic fatty liver disease (NAFLD) refers to a series of diseases, including simple steatosis, caused by the excessive accumulation of fat in hepatocytes, nonalcoholic steatohepatitis with inflammation and fibrosis, and more advanced forms of c
Publikováno v:
Inflammatory Bowel Diseases. 29:S4-S5
Macrophages are the first line of defense against self-stimuli and non-self-pathogens and adopt diverse activation states by reprogramming their cell metabolism and thereby polarizing their phenotypes in order to drive their pro-inflammatory or pro-r
Autor:
Hyun Jung Hong, Minho Shong, Ju Hee Lee, Hyon-Seung Yi, Hail Kim, Hyun-Jin Kim, Chul-Ho Lee, Min Jeong Ryu, Hyo Kyun Chung, Min Jeong Choi, Seong Eun Lee, Seul Gi Kang, Adil Mardinoglu, Saet-Byel Jung, Joon Young Chang, Yong Kyung Kim
Publikováno v:
Diabetologia. 63:837-852
Mitochondrial oxidative phosphorylation (OxPhos) is essential for energy production and survival. However, the tissue-specific and systemic metabolic effects of OxPhos function in adipocytes remain incompletely understood.We used adipocyte-specific C
Autor:
Hyun-Joo Ro, Hyon-Seung Yi, Ju Hee Lee, Min Jeong Choi, Seul Gi Kang, Hyun Jung Hong, Sang Mi Jun, Hail Kim, Jae Myoung Suh, Yea Eun Kang, Minho Shong, Jung Tae Kim, Joon Young Chang, Saet-Byel Jung, Johan Auwerx, Hyo Kyun Chung
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102181-(2021)
iScience, Vol 24, Iss 3, Pp 102181-(2021)
Summary Perturbation of mitochondrial proteostasis provokes cell autonomous and cell non-autonomous responses that contribute to homeostatic adaptation. Here, we demonstrate distinct metabolic effects of hepatic metabokines as cell non-autonomous fac
Autor:
Jingwen Tian, Ji Sun Moon, Ha Thi Nga, Hyo Kyun Chung, Ho Yeop Lee, Jung Tae Kim, Joon Young Chang, Seul Gi Kang, Dongryeol Ryu, Xiangguo Che, Je-Yong Choi, Masayuki Tsukasaki, Takayoshi Sasako, Sang-Hee Lee, Minho Shong, Hyon-Seung Yi
Mitochondrial oxidative phosphorylation (OxPhos) is a critical regulator of skeletal muscle mass and function. Although muscle atrophy due to mitochondrial dysfunction is closely associated with bone loss caused by reduction of mechanical loading, qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d0874622d98033bf973e8a83dd232e2
https://doi.org/10.1101/2020.12.09.417147
https://doi.org/10.1101/2020.12.09.417147