Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hyo Kon Chun"'
Autor:
Soon-Chun Jeong, Kiwoung Yang, Jung-Kyung Moon, Kyoungwhan Back, Hyo-Kon Chun, Namhee Jeong, Sung-Taeg Kang
Publikováno v:
Genes & Genomics. 33:685-692
Despite their medicinal, pharmaceutical, and nutritional importance of isoflavones, the genetic basis controlling the amounts of isoflavones in soybean seeds is still not well understood. The main obstacle is the great variability in the content of i
Publikováno v:
Journal of Life Science. 21:761-765
Salt stability of enzymes is a crucial practical factor in the food industry. Previously, leucine aminopeptidase (LAP) was purified from Bacillus sp. N2. Here, we present the salt effect of LAP using synthetic substrates. LAP had a hydrolytic activit
Autor:
Nack-Shick Choi, Byung-Dae Yoon, Min-Soo Kim, Keug-Hyun Ahn, Hyo Kon Chun, Dong-Min Chung, Hong Jib Kim, Dong Ho Kim, Ki Eun Kim, Hong Bum Koh, Chan Sun Park
Publikováno v:
Biotechnology Letters. 33:1663-1666
A new zymogram method, silver-stained fibrin zymography, for separation of protease bands and activity detection using a single substrate gel, was developed. The method takes advantage of the nanoscale sensitivity of both zymography and silver staini
Quercetin Glucoside Profiling of Fresh Onion (Allium cepa) and Aged Black Onion Using HPLC-ESI/MS/MS
Publikováno v:
Journal of Life Science. 21:464-467
Quercetin is a major flavonoid present in onions, which acts as an antioxidant. Quercetin exists both as a free compound and conjugated with carbohydrates, primarily as glucosides in onion. Aged black onion was made through a 30 day aging process in
Publikováno v:
Journal of Medicinal Food. 13:1532-1536
Chives have been used both as food and as medicine. Previously, two fibrinolytic enzymes, ATFE-I (90 kDa) and ATFE-II (55 kDa), were identified in chives (Allium tuberosum), a perennial herb. In the present work, ATFE-II was purified by ion-exchange
Publikováno v:
Food Science and Biotechnology. 19:697-702
A novel Allium tuberosum fibrinolytic enzyme (ATFE) was purified from the leaf of chive by ion exchange chromatography followed by gel filtration. The molecular mass and iso-electric point (pI) of ATFE were 90 kDa and 4.0 by using 1- or 2-D fibrin zy
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:4085-4090
Because the activation of matrix metalloproteinases (MMP) is a key factor in the metastatic process, compounds with the ability to inhibit MMP activity have a potential in the treatment of tumor. From the examination of 2000 plant extracts, obovatal
Publikováno v:
Molecular Cancer Therapeutics. 5:2666-2675
Matrix metalloproteinase (MMP)-9 plays a key role in tumor invasion. Inhibitors of MMP-9 were screened from Metasequoia glyptostroboides (Dawn redwood) and one potent inhibitor, isoginkgetin, a biflavonoid, was identified. Noncytotoxic levels of isog
Autor:
Ki-Hun Park, Tae-Joung Ha, Hyo-Kon Chun, Seon-Woo Hwang, Hyun-Sook Kwon, Yung-Hee Kho, Min Suk Yang, Jun Lee
Publikováno v:
Journal of Life Science. 16:442-446
Cedrela sinensis is a broadleaf tree that is widely cultivated in Korea and China. It was used for treating enteritis, dysentery, and skin itch in oriental medicine. In this study, three major flavonoids, kaempferol-3-O-rhamnoside (1), quercetin-3-O-
Autor:
Yongseok Choi, Gyoonhee Han, Hyun Seop Tae, Chang Woo Lee, Ky Youb Nam, Yeo Dae Yoon, Hee-Yoon Lee, Hyo-Kon Chun, Ho Jae Lee, Sang Bae Han, Kiho Lee, Hyun Moo Choi, Yung Hee Kho, Song Kyu Park, Hwan Mook Kim, Jae Young Yang
Publikováno v:
Biochemical and Biophysical Research Communications. 341:627-634
The hydroxamic acid analogues (2) of the natural product gelastatins (1) were prepared by 1 step conversion reaction. The synthetic analogues (2) showed potent enzymatic inhibitory activities against MMP-2, MMP-9, and TACE IC50's of 6, 23, and 28 nM,