Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Hyo Jeong Kuh"'
Autor:
Seung Wan Son, Han Yeoung Lee, Sokviseth Moeng, Hyo Jeong Kuh, Soo Young Choi, Jong Kook Park
Publikováno v:
Molecules, Vol 25, Iss 20, p 4701 (2020)
Cancer is a global health concern and one of the main causes of disease-related death. Even with considerable progress in investigations on cancer therapy, effective anti-cancer agents and regimens have thus far been insufficient. There has been comp
Externí odkaz:
https://doaj.org/article/9dcb3691e9db494599a8a877298159e9
Autor:
Sokviseth Moeng, Seung Wan Son, Jong Sun Lee, Han Yeoung Lee, Tae Hee Kim, Soo Young Choi, Hyo Jeong Kuh, Jong Kook Park
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 267 (2020)
Pancreatic cancer is malignant and the seventh leading cause of cancer-related deaths worldwide. However, chemotherapy and radiotherapy are—at most—moderately effective, indicating the need for new and different kinds of therapies to manage this
Externí odkaz:
https://doaj.org/article/c71fc95bfa4b493ca56bd622f667653a
Autor:
Hyun-Ah Kim, Hyunsoo Kim, Min-Kyung Nam, Jong Kook Park, Moo-Yeal Lee, Seok Chung, Kyung-Mi Lee, Hyo-Jeong Kuh
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Recently, natural killer (NK) cells emerged as a treatment option for various solid tumors. However, the immunosuppressive tumor immune microenvironment (TIME) can reduce the cytotoxic ability of NK cells in pancreatic ductal aden
Externí odkaz:
https://doaj.org/article/bb165477e87e4daa92807e3fad1d43ca
Autor:
Kwang-Seock Kim, Si Hyoung Kim, Chang-Nim Im, Kun Na, Moo-Yeal Lee, Jong Kook Park, Hyo-Jeong Kuh
Publikováno v:
Biochemical and Biophysical Research Communications. 647:30-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95aa5d90badbae1e82cca9a445be28bb
https://doi.org/10.1016/j.bbrc.2023.01.063
https://doi.org/10.1016/j.bbrc.2023.01.063
Publikováno v:
Journal of Pharmaceutical Investigation. 51:541-553
Cancer nanomedicines (NMs) have emerged as potential anticancer therapeutics with advantages of tumor-targeting drug delivery for improved efficacy against human solid tumors. Despite promising data obtained in preclinical studies, few clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8330226a1b8457675202f00d1e45ef3c
https://doi.org/10.1007/s40005-021-00534-y
https://doi.org/10.1007/s40005-021-00534-y
Luteolin-regulated MicroRNA-301-3p Targets Caspase-8 and Modulates TRAIL Sensitivity in PANC-1 Cells
Autor:
Jong Kook Park, Seung Wan Son, Sokviseth Moeng, Jong Sun Lee, Chung Kwon Kim, Hyun Ah Seo, Hyo Jeong Kuh
Publikováno v:
Anticancer Research. 40:723-731
Background/aim MicroRNAs (miRNAs) play regulatory roles in pancreatic ductal adenocarcinoma (PDAC). However, it is still required to identify the function of miRNA-301-3p in pancreatic cancer cells. Materials and methods Effects of luteolin on cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ea782dae28f2b4842c5eec890162e7
https://doi.org/10.21873/anticanres.14003
https://doi.org/10.21873/anticanres.14003
Autor:
Jeeyeun Song, Iftikhar Ali Khawar, Jong Kook Park, So-Dam Jang, Hyo-Jeong Kuh, Chang-Nim Im, Hyun-Ah Kim
Publikováno v:
Cancers, Vol 13, Iss 5955, p 5955 (2021)
Cancers
Cancers; Volume 13; Issue 23; Pages: 5955
Cancers
Cancers; Volume 13; Issue 23; Pages: 5955
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, with a five-year survival rate of less than 8%. There is a need to develop drugs with anti-invasive activity and in vitro tumor models for effective drug sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9610c8ac273824bc95baa84cfab07a5
https://www.mdpi.com/2072-6694/13/23/5955
https://www.mdpi.com/2072-6694/13/23/5955
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9819, p 9819 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Hypoxia-inducible factor-1 alpha (HIF-1α) is overexpressed in cancer, leading to a poor prognosis in patients. Diverse cellular factors are able to regulate HIF-1α expression in hypoxia and even in non-hypoxic conditions, affecting its progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0964abf28065ffdf780e92256175bd9c
https://www.mdpi.com/1422-0067/22/18/9819
https://www.mdpi.com/1422-0067/22/18/9819
Publikováno v:
Biochemical and Biophysical Research Communications. 515:183-189
Heterotypic cell-cell interaction between cancer cells and pancreatic stellate cells (PSCs) within tumor microenvironment is considered as a key mechanism for epithelial-mesenchymal transition (EMT) that triggers disease progression and chemoresistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcfe04a27c79a3dbfa1c9a006e0934e
https://doi.org/10.1016/j.bbrc.2019.05.101
https://doi.org/10.1016/j.bbrc.2019.05.101
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Pancreatic ductal adenocarcinoma (PDAC) is a stroma-rich carcinoma, and pancreatic stellate cells (PSCs) are a major component of this dense stroma. PSCs play significant roles in metastatic progression and chemoresistance through cross-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04acb32424c639ef3952a98666b0c291
http://link.springer.com/article/10.1186/s13046-019-1225-9
http://link.springer.com/article/10.1186/s13046-019-1225-9