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pro vyhledávání: '"Hyo H. Chung"'
Autor:
Eugene Zhukovsky, Araz Eivazi, Alice Kim, Lisa Cherry, Omid Vafa, Peter Cheung, Jost Vielmetter, Paul Michael Steed, Sandhya Kashi, Arthur J. Chirino, Jonathan Zalevsky, John R. Desjarlais, Linus Hyun, Marian Hwang, Christina Abbott, Rend S. Hubert, Esther Kim, David E. Szymkowski, Sarah X. Gao, C. O'Brien, James Kung, Hyo H. Chung, Malú G. Tansey, Donald O'keefe, Sean Yoder, Stephen K. Doberstein, David F. Carmichael, Karen Singer, Anton Filikov, T. Umesh S. Muchhal, Duc-Hanh T. Nguyen, Cheryl Chan, Sabrina P. Martinez, Bassil I. Dahiyat
Publikováno v:
Science (New York, N.Y.). 301(5641)
Tumor necrosis factor (TNF) is a key regulator of inflammatory responses and has been implicated in many pathological conditions. We used structure-based design to engineer variant TNF proteins that rapidly form heterotrimers with native TNF to give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde7bbe8096068d11314ae2a672bda88
https://pubmed.ncbi.nlm.nih.gov/14512626
https://pubmed.ncbi.nlm.nih.gov/14512626
